Feinberg WM, Blackshear JL, Laupacis A, et al. Prevalence, age distribution and gender of patients with atrial fibrillation: analysis and implications. Arch Intern Med. 1995;155:469–73. https://doi.org/10.1001/archinte.1995.00430050045005.
Article
CAS
PubMed
Google Scholar
Wolf PA, Abbot RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham study. Stroke. 1991;22:983–8. https://doi.org/10.1161/01.STR.22.8.983.
Article
CAS
PubMed
Google Scholar
Lin HJ, Wolf PA, Kelly-Hayes M, et al. Stroke severity in atrial fibrillation. The Framingham Study. Stroke. 1996;27:1760–4.
Article
CAS
PubMed
Google Scholar
Steinberg BA, Greiner MA, Hammill BG, et al. Contradindications to anticoagulation therapy and eligibility for novel anticoagulants in older patients with atrial fibrillation. Cardiovasc Ther. 2015;33:177–83. https://doi.org/10.1111/1755-5922.12129.
Article
CAS
PubMed
Google Scholar
Bassand J-P, Accetta G, Al Mahmeed W, et al. Risk factors for death, stroke, and bleeding in 28,628 patients from the GARFIELD-AF registry: rationale for comprehensive management of atrial fibrillation. PLoS One. 2018;13(1):e0191592. https://doi.org/10.1371/journal.pone.0191592.
Article
CAS
PubMed
PubMed Central
Google Scholar
Yu AYX, Malo S, Svenson LW, et al. Temporal trends in the use and comparative effectiveness of direct oral anticoagulant agents versus warfarin for nonvalvular atrial fibrillation: a Canadian population-based study. J Am Heart Assoc. 2017;6:e007129. https://doi.org/10.1161/JAHA.117.007129.
Article
PubMed
PubMed Central
Google Scholar
Ogilvie IS, Newton N, Welner SA, et al. Underuse of oral anticoagulants in atrial fibrillation: a systematic review. Am J Med. 2010;123:638–45. https://doi.org/10.1016/j.amjmed.2009.11.025.
Article
CAS
PubMed
Google Scholar
Xian Y, O’Brien EC, Liang L, Xu H, et al. Association of preceding antithrombotic treatment with acute ischemic stroke severity and in-hospital outcomes among patients with atrial fibrillation. JAMA. 2017;317(10):1057–67. https://doi.org/10.1001/jama.2017.1371.
Article
PubMed
Google Scholar
Katz DF, Maddox TM, Turakhia M, et al. Contemporary trends in oral anticoagulant prescription in atrial fibrillation patients at low to moderate risk of stroke after guideline-recommended change in Use of the CHADS2 to the CHADS2-vasc score for thrombotic risk assessment: Analysis from the National Cardiovascular Data Registry’s Outpatient Practice Innovation and Clinical Excellence Atrial Fibrillation Registry. Circul Cardiovasc Qual Outcomes. 2017;10:e003476. https://doi.org/10.1161/CIRCOUTCOMES.116.003476.
Article
Google Scholar
Lubitz SA, Khurshid S, Weng C, et al. Predictors of oral anticoagulant non prescription in patients with atrial fibrillation and elevated stroke risk. Am Heart J. 2018;200:24–31. https://doi.org/10.1016/j.ahj.2018.03.00.
Article
PubMed
PubMed Central
Google Scholar
López-López José A, Sterne JAC, Thom HHZ, et al. Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis. BMJ. 2017;359. https://doi.org/10.1136/bmj.j505.
Ezekowitz MD, Kent AP. The impact of IMPACT-AF. Lancet. 2017;390:1717–8. https://doi.org/10.1016/S0140-6736(17)32248-1.
Article
PubMed
Google Scholar
O’Brien MA, Rogers S, Jamtvedt G, et al. Educational outreach visits: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2007;4:CD000409. https://doi.org/10.1002/14651858.CD000409.pub2.
Article
Google Scholar
Ivers N, Jamtvedt G, Flottorp S, et al. Audit and feedback: effects on professional practice and healthcare outcomes. Cochrane Database Syst Rev. 2012;6:CD000259. https://doi.org/10.1002/14651858.CD000259.pub3.
Article
Google Scholar
Flodgren G, Parmelli E, Doumit G, et al. Local opinion leaders: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2011;8:CD000125. https://doi.org/10.1002/14651858.CD000125.pub4.
Article
Google Scholar
Ornstein S, Jenkins RG, Nietert PJ, et al. A multimethod quality improvement intervention to improve preventive cardiovascular care: a cluster randomised trial. Ann Intern Med. 2004;141:523–32. https://doi.org/10.7326/0003-4819-141-7-200410050-00008.
Article
PubMed
Google Scholar
Wright J, Bibby J, Eastham J, et al. Multifaceted implementation of stroke prevention guidelines in primary care: cluster-randomised evaluation of clinical and cost effectiveness. Qual Saf Health Care. 2007;16:51–9. https://doi.org/10.1136/qshc.2006.019778.
Article
PubMed
PubMed Central
Google Scholar
Jackson SL, Peterson GM, Vial JH. A community-based educational intervention to improve antithrombotic drug use in atrial fibrillation. Ann Pharmacother. 2004;38:1794–9. https://doi.org/10.1345/aph.1E152.
Article
PubMed
Google Scholar
Joubert J, Reid C, Barton D, et al. Integrated care improves risk-factor modification after stroke: initial results of the integrated Care for the Reduction of secondary stroke model. J Neurol Neurosurg Psychiatry. 2009;80:279–84. https://doi.org/10.1136/jnnp.2008.148122.
Article
CAS
PubMed
Google Scholar
Gattellari M, Worthington JM, Leung DY, et al. Supporting treatment decision making to optimise the prevention of stroke in atrial fibrillation: the STOP STROKE in AF study. Protocol for a cluster randomised controlled trial. Implement Sci. 2012;7:63. https://doi.org/10.1186/1748-5908-7-63.
Article
PubMed
PubMed Central
Google Scholar
Australian Institute of Health and Welfare. Medical workforce 2011. National health workforce series no. 3. Cat. No. HWL 49. Canberra: AIHW; 2013.
Google Scholar
Britt H, Miller GC, Henderson J, et al. A decade of Australian general practice activity 2004–05 to 2013–14. General practice series no. 37. Sydney: Sydney University Press; 2014.
Google Scholar
Gage BF, Waterman AD, Shannon W, et al. Validation of clinical classification schemes for predicting stroke: results from the National Registry of atrial fibrillation. JAMA. 2001;285:2864–70. https://doi.org/10.1001/jama.285.22.2864.
Article
CAS
PubMed
Google Scholar
Hart RG, Pearce LA, Aguilar MI. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med. 2007;146:857–67.
Article
PubMed
Google Scholar
Albers GW, Amarenco P, Easton JD, et al. American College of Chest Physicians: antithrombotic and thrombolytic therapy for ischemic stroke: American College of Chest Physicians Evidence-based Clinical Practice Guidelines (8th edition). Chest. 2008;13:630S–69S. https://doi.org/10.1378/chest.11-2302.
Article
CAS
Google Scholar
Gallus AS, Baker RI, Chong BH, On behalf of the Australasian Society of Thrombosis and Haemostatis: Position statement, et al. Consensus guidelines for warfarin therapy. Recommendations from the Australasian Society of Thrombosis and Haemostatis. Med J Aust. 2000;172:600–5.
Article
CAS
PubMed
Google Scholar
McAlister FA, Man-Son-Hing M, Straus SE, for the Decision Aid in Atrial Fibrillation (DAAFI) Investigators, et al. Impact of a patient decision aid on care among patients with nonvalvular atrial fibrillation: a cluster randomised trial. CMAJ. 2005;173:496–501. https://doi.org/10.1503/cmaj.050091.
Article
PubMed
PubMed Central
Google Scholar
Lip GY, Nieuwlaat R, Pisters R, et al. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation. Chest. 2010;137(2):263–72. https://doi.org/10.1378/chest.09-1584.
Article
PubMed
Google Scholar
Dolan JG. Method for evaluating health care providers’ decision making: the provider decision process assessment instrument. Med Decis Mak. 1991;19:38–41. https://doi.org/10.1177/0272989X9901900105.
Article
Google Scholar
Dupont WD, Plummer WD. Power and sample size calculations: a review and computer program. Control Clin Trials. 1990;11:116–28. https://doi.org/10.1016/0197-2456(90)90005-M.
Article
CAS
PubMed
Google Scholar
Olaiya MT, Kim J, Nelson MR, et al. Effectiveness of a shared team approach between nurses and doctors for improved risk factor management in survivors of stroke: a cluster randomised controlled trial. Eur J Neurol. 2017;24:920–8. https://doi.org/10.1111/ene.13306.
Article
CAS
PubMed
Google Scholar
Wolfe CDA, Redfern J, Rudd AG, et al. Cluster randomised controlled trial of a patient and general practitioner intervention to improve the management of multiple risk factors after stroke: stop stroke. Stroke. 2010;41:2470–6. https://doi.org/10.1161/STROKEAHA.110.588046.
Article
PubMed
Google Scholar
Majumdar SR, Tsuyuki RT, McAlister FA. Impact of opinion leader-endorsed evidence summaries on the quality of prescribing for patients with cardiovascular disease: a randomised controlled trial. Am Heart J. 2007;153(22):e1–8. https://doi.org/10.1016/j.ahj.2006.07.030.
Article
Google Scholar
Karlsson D, Nilsson S, Bang M, et al. A clinical decision support tool for improving adherence to guidelines on anticoagulant therapy in patients with atrial fibrillation at risk of stroke: a cluster randomised trial in a Swedish primary care setting (the GDS-AF study). PLoS Med. 2018;15:e1002528. https://doi.org/10.1371/journal.pmed.1002528.
Article
PubMed
PubMed Central
Google Scholar
Bajorek BV, Magin PJ, Hilmer SN, et al. Optimizing stroke prevention in patients with atrial fibrillation: a cluster randomised controlled trial of a computerized antithrombotic risk assessment tool in Australian general practice, 2012-2013. Prev Chronic Dis. 2016;13:E90. https://doi.org/10.5888/pcd13.160078.
Article
PubMed
PubMed Central
Google Scholar
Ashburner JM, Atlas SJ, Khurshid S, et al. Electronic physician notifications to improve guideline-based anticoagulation in atrial fibrillation: a randomised controlled trial. J Gen Intern Med. 2018. https://doi.org/10.1007/s11606-018-4612-6.
Holt TA, Dalton A, Marshall T, et al. Automated software system to promote anticoagulation and reduce stroke risk: cluster randomised controlled trial. Stroke. 2017;48:787–90. https://doi.org/10.1161/STROKEAHA.116.015468.
Article
PubMed
PubMed Central
Google Scholar
Arts DL, Abu-Hanna A, Medlock SK, et al. Effectiveness and usage of a decision support system to improve stroke prevention in general practice: a cluster randomised controlled trial. PLoS One. 2017;12:e0170974. https://doi.org/10.1371/journal.pone.0170974.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kapoor A, Amroze A, Golden J, Crawford S, O’Day K, Elhag R, Nagy A, Lubitz SA, Saczynski JS, Mathew J, McManus DD. Support-AF: piloting a multi-faceted, electronic medical record-based intervention to improve prescription of anticoagulation. J Am Heart Assoc. 2018;7:e009946. https://doi.org/10.1161/JAHA.118.009946.
Article
PubMed
PubMed Central
Google Scholar
Lansberg MG, O’Donnell MJ, Khatri P, et al. Antithrombotic and thrombolytic therapy for ischemic stroke: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians. Chest. 2012;141(2 Suppl):e601S–36S. https://doi.org/10.1378/chest.11-2302.
Article
CAS
PubMed
PubMed Central
Google Scholar
January CT, Wann LS, Calkins H, Chen LY, Cigarroa JE, et al. AHA/ACC/HRS Focused opdate of the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation. Circulation 2019;140:e125–e151.
Article
PubMed
Google Scholar
Lip GYH, Pan X, Kamble S, Kawabata H, et al. Discontinuation risk comparison among ‘real-world’ newly anticoagulated atrial fibrillation patients: Apixaban, warfarin, dabigatran, or rivaroxaban. PLoS One. 2018;13:e0195950. https://doi.org/10.1371/journal.pone.0195950.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lacoin L, Lumley M, Ridha E, et al. Evolving landscape of stroke prevention in atrial fibrillation within the UK between 2012 and 2016: a cross-sectional analysis study using CPRD. BMJ Open. 2017;7:e015363. https://doi.org/10.1136/bmjopen-2016-015363.
Article
PubMed
PubMed Central
Google Scholar
Sur NB, Wang K, Di Tullio MR, et al. Disparities and temporal trends in the use of anticoagulation in patients with ischemic stroke and atrial fibrillation. Stroke. 2019;50:1452–9. https://doi.org/10.1161/STROKEAHA.118.023959.
Article
CAS
PubMed
PubMed Central
Google Scholar
Aronis KN, Hylek EM. Evidence gaps in the era of non–vitamin K Oral anticoagulants. J Am Heart Assoc. 2018;7:e007338. https://doi.org/10.1161/JAHA.117.007338.
Article
PubMed
PubMed Central
Google Scholar
Vinereanu D, Lopes RD, Bahit MC, et al. A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation (IMPACT-AF): an international, cluster randomised trial. Lancet. 2017;390:1737–46. https://doi.org/10.1016/S0140-6736(17)32165-7.
Article
PubMed
Google Scholar
Vinogradova Y, Coupland C, Hill T, Cox JH. Risks and benefits of direct oral anticoagulants versus warfarin in a real world setting: cohort study in primary care. BMJ. 2018;362. https://doi.org/10.1136/bmj.k2505.
Pol D, Curtis C, Ramukumar S, Bittinger L. NOACs now mainstream for the use of anticoagulation in non-valvular atrial fibrillation in Australia. Heart Lung Circul. 2018. https://doi.org/10.1016/j.hlc.2018.03.010.
Morgan A, Joshy G, Schaffer A, et al. Rapid and substantial increases in anticoagulant use and expenditure in Australia following the introduction of new types of oral anticoagulants. PLoS One. 2018;13(12):e0208824. https://doi.org/10.1371/journal.pone.0208824.
Article
PubMed
PubMed Central
Google Scholar
Ashburner JM, Singer DE, Lubitz SA, et al. Changes in use of anticoagulation in patients with atrial fibrillation within primary care network associated with the introduction of direct oral anticoagulants. Am Coll Cardiol. 2017;120:786–91. https://doi.org/10.1016/j.amjcard.2017.05.055.
Article
Google Scholar
Douros A, Renoux C, Coulombe J, Suissa S. Patterns of long-term use of non-vitamin K antagonist oral anticoagulants for non-valvular atrial fibrillation: Quebec observational study. Pharmacoepidemiol Drug Safety. 2017;26:1546–54. https://doi.org/10.1002/pds.4333.
Article
CAS
Google Scholar
Zhu J, Alexander GC, Nazarian S, Segal JB. Trends and variation in oral anticoagulant choice in patients with atrial fibrillation. 2010-2017. Pharmacotherapy. 2018;38:907–20. https://doi.org/10.1002/phar.2158.
Article
PubMed
PubMed Central
Google Scholar
Huiart L, Ferdynus C, Renoux C, et al. Trends in initiation of direct oral anticoagulant therapies for atrial fibrillation in a national population-based cross-sectional study in the French health insurance databases. BMJ Open. 2018;8:e018180. https://doi.org/10.1136/bmjopen-2017-018180.
Article
PubMed
PubMed Central
Google Scholar
Pratt NL, Ramsay EN, Caughey GE, Roughead EE. Uptake of novel oral anticoagulants in Australia. Med J Aust. 2016;204:104–5. https://doi.org/10.5694/mja15.01000.
Article
PubMed
Google Scholar
Zhang Y, Mendéz SJ, Scott A. Factors affecting general practitioners’ decisions to adopt new prescription drugs – cohort analyses using Australian longitudinal physician survey data. BMC Health Serv Res. 2019;19:94. https://doi.org/10.1186/s12913-019-3889-4.
Article
PubMed
PubMed Central
Google Scholar
Wutzler A, Krogias C, Grau A, Veltkamp R, Heuschmann PU, Haeusler KG. Stroke prevention in patients with acute ischemic stroke and atrial fibrillation in Germany – a cross-sectional survey. BMC Neurol. 2019;19:25. https://doi.org/10.1186/s12883-019-1249-y.
Article
PubMed
PubMed Central
Google Scholar
Pratt NL, Ramsay E, Ellett LMK, et al. Comparative effectiveness and safety of low-strength and high-strength direct oral anticoagulants compared with warfarin: a sequential cohort study. BMJ Open. 2019;9:e0264886. https://doi.org/10.1136/bmjopen-2018-026486.
Article
Google Scholar
Shpak M, Ramakrishnan A, Nadasdy Z, Cowperthwaite M, Fanale C. Higher incidence of ischemic stroke in patients taking novel oral anticoagulants. Stroke. 2018;49:2851–6. https://doi.org/10.1161/STROKEAHA.118.022636.
Article
CAS
PubMed
Google Scholar
Sato T, Aizawa Y, Fuse K, Fujita S, Ikeda Y, Kitazawa H, Takahashi M, Okabe M. The comparison of inappropriate low dose use among 4 direct oral anticoagulants in patients with atrial fibrillation: from the database of a single centre registry. J Stroke Cerebrovasc Dis. 2018;27:3280–8. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.07.028.
Article
PubMed
Google Scholar
Barra ME, Fanikos J, Connors JM, Sylvester KW, Piazza G, Goldhaber SZ. Evaluation of dose-reduced direct oral anticoagulant therapy. Am J Med. 2016;129:1198–204. https://doi.org/10.1016/j.amjmed.2016.05.041.
Article
CAS
PubMed
Google Scholar
Pattullo CS, Barras M, Tai B, McKean M, Donovan P. New oral anticoagulants: appropriateness of prescribing in real-world setting. Intern Med J. 2016;46:812–8. https://doi.org/10.1111/imj.13118.
Article
CAS
PubMed
Google Scholar
Nielsen PB, Skjøth F, Søgaard M, et al. Effectiveness and safety of reduced dose non-vitamin K oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study. BMJ. 2017;357:j510. https://doi.org/10.1136/bmj.j510.
Article
Google Scholar
Yao X, Abraham NS, Alexander GC, Crown W, Montori VM, Sangaralingham LR, Gersh BJ, Shah ND, Noseworthy PA. Effect of adherence to oral anticoagulants on risk of stroke and major bleeding among patients with atrial fibrillation. J Am Heart Assoc. 2016;5:e003074. https://doi.org/10.1161/JAHA.115.003074.
Article
PubMed
PubMed Central
Google Scholar
Lip GYH, Banerjee A, Boriani G, et al. Antithrombotic therapy for atrial fibrillation. chest guideline and expert panel report. Chest. 2018;154:1121–201. https://doi.org/10.1016/j.chest.2018.07.040.
Article
PubMed
Google Scholar
Marcucci M, Lip GYH, Nieuwlaat R, et al. Stroke and bleeding risk co-distribution: real world patients with atrial fibrillation. Am J Med. 2014;127:979–86. https://doi.org/10.1016/j.amjmed.2014.05.003.
Article
PubMed
Google Scholar
Family Medicine Research Centre. SAND Abstract No. 174 from the BEACH program 2010–11. Subject: Atrial fibrillation/flutter in general practice patients. The University of Sydney. https://sydney.edu.au/medicine/fmrc/publications/sand-abstracts/174-Atrial_fibrillation_flutter.pdf Accessed 10/10/2019.
Mills L, Meiser B, Ahmad R, et al. A cluster randomised controlled trial of an online psychoeducational intervention for people with a family history of depression. BMC Psychiatry. 2019;19:29. https://doi.org/10.1186/s12888-018-1994-2.
Article
PubMed
PubMed Central
Google Scholar
Pond D, Mate K, Stocks N, et al. Effectiveness of a peer-mediated educational intervention in improving general practitioner diagnostic assessment and management of dementia: a cluster randomised controlled trial. BMJ Open. 2018;8:e021125. https://doi.org/10.1136/bmjopen-2017-021125.
Article
PubMed
PubMed Central
Google Scholar
Treweek S, Bevan S, Bower P, et al. Trial forge guidance 1: what is a study within a trial (SWAT). Trials. 2018;19:139. https://doi.org/10.1186/s13063-018-2535-5.
Article
PubMed
PubMed Central
Google Scholar
Gadsbøll K, Staerk L, Fosbøl EL, et al. Increased use of oral anticoagulants in patients with atrial fibrillation: temporal trends from 2005 to 2015 in Denmark. Eur Heart J. 2017;38:899–906.
PubMed
Google Scholar
Steinberg BA, Shrader P, Pieper K, et al. Frequency and outcomes of reduced dose non-vitamin K antagonist anticoagulants: results from ORBIT-AF II (The outcomes registry for better informed treatment of atrial fibrillation II). J Am Heart Assoc. 2018;7:e007633. https://doi.org/10.1161/JAHA.117.007633.
Article
CAS
PubMed
PubMed Central
Google Scholar