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Table 2 Responses of general practitioners regarding not prescribing Isotretinoin in their practice

From: Practice and attitude of general practitioners towards initiating isotretinoin for acne vulgaris in Fars province, Iran: cross-sectional study

Question

Response

Frequency (%); Nā€‰=ā€‰223

Why would you not prescribe Isotretinoin?

Not being aware that GPs have permission to prescribe it

58 (74)

Worries regarding liver dysfunction

122 (54.7)

Worries regarding its teratogenicity

83 (37.2)

Lack of knowledge of the drug

70 (31.4)

Worries regarding abnormal lipid profile

46 (20.6)

I am not interested

47 (21.1)

Being wary of the legal complaints

37 (16.6)

No coverage by insurance companies

23 (10.3)

Worries regarding mucocutaneous dryness

22 (9.9)

Worries regarding workload

10 (4.5)

Being wary of suicidality

8 (3.6)

Not having relevant patients

8 (3.2)

I believe only dermatologists should prescribe it

10 (3.1)

There was no need for my patients to start Isotretinoin

7(2.8)

Not having accurate follow-up

2 (0.8)

Drug side effects

2 (0.8)

Not in my experience field

1 (0.4)

Are you interested in prescribing Isotretinoin in your future primary care visits?

No

114 (51.1)

Yes

109 (48.9)

What would persuade you to prescribe Isotretinoin?

Guideline from health care systems

111 (49.8)

Complementary educations

103 (46.2)

The guidance of a dermatologist, if needed

103 (46.2)

Proper support from the Food and Drug Administration (FDA) and forensic medicine

67 (30)

Financial aid

16 (7.2)

Proper follow-up

2 (0.8)

Proper knowledge of the drug

1 (0.4)

Higher efficacy compared to other drugs of choice

1 (0.4)

Patientā€™s request

1 (0.4)

Indication for starting Isotretinoin

1 (0.4)

None of the above

30 (13.4)

Do you believe that Isotretinoin should only be administered by a specialist?

Yes

122 (54.7)

No

101 (45.3)

In your opinion, what are the requirements for GPs who prescribe Isotretinoin?

Complementary education in Dermatology

105 (47.1)

Previous experience in working under a dermatologist supervision

82 (36.8)

being a member of dermatology associations

21 (9.4)

Interest in the dermatology field

18 (8.1)

Being aware of the drug information (indication, blood tests, and follow-up)

7 (2.8)

Obeying the guideline

1 (0.4)

Insufficient education in this regard

1 (0.4)

No response in first-line treatment options

1 (0.4)

None of the above

76 (34)

Are you aware that Isotretinoin is being prescribed in primary care centers?

Yes

109 (48.9)

No

114 (51.1)

Do you believe that primary care settings can prescribe Isotretinoin safely?

Yes

105 (47.1)

No

118 (52.9)

Do you believe there are safety measures in the primary care setting for prescribing Isotretinoin?

Yes

134 (60.1)

No

89 (39.9)

Would it be beneficial if Isotretinoin were used vastly in primary care settings?

Yes

107 (48)

No

116 (52)

Would the specialists support Isotretinoin usage in primary care settings?

Yes

55 (24.7)

No

168 (75.3)