Table 7 Effects of interprofessional collaborations in patients with symptoms of mental or physical distress

Adler 2004 [70]

Antidepressant use rates at 6 months

I = 57,5% C = 46,2%

p = 0,025

Modification of the Beck Depression Inventory (BDI) at 6 months

I = 17.7 C = 19.4

NS

Aragonès 2019 [71]

Depression at 12 months

Remission rate (HSCL-20 < 0.5)

I = 20.1% C = 11.1% OR = 2.13 95% CI [0.94—4.85]

p = 0.070

Response to treatment (50% reduction HSCL-20)

I = 39.6% C = 20.7% OR = 2.74 95% CI [1.12—6.67]

p = 0.027

Pain at 12 months

Response to treatment (30% reduction BPI)

I = 18.7% C = 18.5% OR = 1.02 95% CI [0.46—2.26)

NS

Areán 2007 [72]

Patients at 12 months:

NOT POOR(NP) / POOR (P) patients

Use of antidepressant (%)

NP:I = 65 C = 49 Ad. OR = 2.17 95%CI [1.53—3.08]

p < 0.001

Use of psychotherapy (%)

P:I = 68 C = 48 Ad. OR = 3.25 95%CI[2.14—4.96]

p < 0.001

Depressive symptoms = SCL-20

NP:I = 44 C = 16 Ad. OR = 4.33 95%CI[3.14—5.97]

p < 0.001

Health-related functional impairment = General health self-ratings

P:I = 40 C = 15 Ad. OR = 4.16 95%CI[2.52—6.85]

p < 0.001

NP:I = 0.95 C = 1.36 Ad. OR = –0.41 95%CI[–0.49—–0.33]

p < 0.001

P:I = 1.07 C = 1.45 Ad. OR = –0.39 95%CI[–0.50—–0.27]

p < 0.001

PCS-12

NP:I = 3.06 C = 3.38 Ad. OR = -0.32 95%CI[–0.43—–0.21]

p < 0.001

P:I = 3.40 C = 3.69 Ad. OR = -0.29 95%CI[–0.45—–0.12]

p < 0.001

NP:I = 41.74 C = 39.88 Ad. OR = 1.67 95%CI[0.78—2.55]

p < 0.001

P:I = 38.99 C = 37.76 Ad. OR = 1.46 95%CI[0.33—2.60]

p < 0.001

Chan 2011 [73]

HADS (Hospital Anxiety and Depression Scale)

6 months

I = 21.5 C = 17.5

0.061

12 months

I = 19.5 C = 17.9

NS

Engel 2016 [74]

Posttraumatic Diagnostic Scale (PDS) at 12 months

I = -6.07 C = -3.54 OR 1.62 95%CI [1.08–2.43]

p = 0.02

Symptom Checklist Depression Scale (SCL-20) at 12 months

I = -0.56 C = -0.31 OR 1.65 95%CI [1.13–2.42]

p = 0.01

Finley 2002 [75]

Medication possession ratios

I = 0.811 C = 0.659

p < 0.005

Variation of the nb of primary care visits

I = -39.4% C = -12.2%

p < 0.007

Finley 2003 [76]

Compliance early phase

I = 76% C = 60% OR 2.11, 95%CI [ 0.97–4.58]

p = 0.057

Compliance continuation phase

I = 67% C = 48% OR 2.17, 95%CI [1.04–4.51]

p = 0.038

MPR (medication possession ratio) at 3 months

I = 0.92 C = 0.89

p = 0.48

MPR at 6 months

I = 0.83 C = 0.77

p = 0.26

Change of antidepressants

I = 19% C = 4%

p = 0.016

Resource utilization

I = 5% C = 24%

p = 0.54

Kolk 2004 [77]

Pre-test to 12 months

Self-reported

I = 27,77 to 19.9 C = 25.19 to 21.00

NS

unexplained symptoms

I = 22.55 to 15.39 C = 20.44 to 13.56

NS

anxiety

I = 38.90 to 25.93 C = 34.56 to 23.12

NS

depression

Registered

I = 4.39 to 1.95 C = 2.73 to 0.87

NS

unexplained symptoms

I = 1.88 to 1.20 C = 1.47 to 1.53

NS

explained symptoms

I = 4.95 to 3.39 C = 3.80 to 2.93

NS

nb of consultations

Marklund 1999 [78]

Number of sick days

Intervention group 63.8 / control group 92.8

0.006

Morgan 2013 [79]

PHQ-9 (Ancova)

I = 14,4 to 8,7 C = 15,1 to 10,8

p = 0,047

Petersen 2014 [80]

PACIC = Patient Assessment of Chronic Illness Care

I = 3.12 C = 2.86

p = 0.019

Morisky patient self-report scale (Medication adherence)

I = 2.59 C = 2.65

NS

Prescribed antidepressant medications

I = 60.2% C = 55.1%

NS

Visits to the family physician

I = 15.96 C = 14.46

NS

Visits to the mental health specialists

I = 3.01 C = 0.94

NS

Rollman 2005 [81]

Hamilton Anxiety Rating Scale

-3,6 [-6,4; -0,8] / effect size (95% CI): 0,38 [0,09; 0,67]

p = 0,01

Schaefert 2013 [82]

At 12 months quality of life:

Change in PCS (physical health part of SF-36)

I = 44.56 C = 44.14 Ad. OR = 0.32 95%CI[–1.20—1.84]

NS

Change in MCS (mental health part of SF-36)

I = 46.59 C = 42.09 Ad. OR = 2.30 95%CI [0.34—4.26]

p = 0.0226

Sherbourne, 2001 [83]

Clinical depression at 2 years (CIDI)

I (meds) = 39%, I(therapy) = 31%, C = 34%

NS

Simon 1998 [84]

Unable to work due to illness

OR 0.60 [0.40, 0.91]

NS

Had to change work due to illness

OR 0.80 [0.49, 1.33]

NS

Cut down on activities due to illness

OR 0.68 [0.46, 0.99]

S

Rating health fair or poor

OR 0.94 [0.68, 1.29]

NS

Somatic symptoms

OR 0.69 [0.48, 0.98]

S

Pain symptoms

OR 0.83 [0.63, 1.09]

NS

Missing work/school

OR 1.25 [0.52, 3.09]

NS

Restricting daily activities

OR 1.04 [0.20, 5.33]

NS

OR 1.14 [0.38, 3.40]

NS