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Table 2 Patient self-assessment and expectation, clinical assessment by the GPs and GAS-results in study throat swabs

From: Influence of a guideline or an additional rapid strep test on antibiotic prescriptions for sore throat: the cluster randomized controlled trial of HALS (Hals und Antibiotika Leitlinien Strategien)

 

Guideline

(GL-group)

N = 189

Guideline + RADT

(GL-RADT-group)

N = 172

Usual care

(UC-group)

N = 159

Total

N = 520

p-value*

Patients’ self-assessment and expectations***

 Severe discomfort

148/175 (85)

149/162 (92)

130/150 (87)

427/487 (88)

0.107

 Wish for a relieving remedy

154/178 (87)

153/165 (93)

124/150 (83)

431/493 (87)

0.024

 Wish to get an antibiotic

62/178 (35)

52/163 (32)

42/146 (29)

156/486 (32)

0.486

Clinical assessment by the GPs

 Days of sore throat until consultation [Mean ± SD]

3.3 ± 2.6

2.9 ± 1.9

2.7 ± 2.3

3.0 ± 2.3

0.030**

 1–3 days

127/182 (70)

123/168 (73)

119/155 (77)

369/505 (73)

0.474

 4–7 days

46/182 (25)

41/168 (24)

30/155 (19)

117/505 (23)

 8–14 days

9/182 (5)

4/168 (2)

6/155 (4)

19/505 (4)

Severity of sore throat

 mild

12/180 (7)

9/169 (5)

5/154 (3)

26/503 (5)

0.312

 moderate

60/180 (33)

49/169 (29)

59/154 (38)

168/503 (33)

 severe

108/180 (60)

111/169 (66)

90/154 (58)

309/503 (61)

General impairment by the illness

 moderate

93/182 (51)

74/164 (45)

78/152 (51)

245/498 (49)

0.444

 severe

89/182 (49)

90/164 (55)

74/152 (49)

253/498 (51)

Fever ≥ 38 °C

    

 actual or in history

52/189 (28)

68/172 (40)

53/159 (33)

173/520 (34)

0.167

 not reported

25/189 (13)

22/172 (13)

18/159 (11)

65/520 (13)

Centor- or McIsaac Score

 ≤ 2

101/189 (53)

69/172 (40)

data not

170/361 (47)

 ≤ 0.001

 ≥ 3

67/189 (35)

95/172 (55)

collected

162/361 (45)

 not reported

21/189 (11)

8/172 (5)

 

29/361 (8)

Suspicion of GAS pharyngitis by GP

77/174 (44)

82/161 (51)

54/154 (35)

213/489 (44)

0.017

Study throat swab

 Cultures positive for GAS

29/184 (16)

26/161 (16)

21/154 (14)

76/499 (15)

0.799

  1. Figures are numbers (percentages), unless stated otherwise. SD standard deviation, *Chi2 test unless indicated, **Univariate analysis of variance, ***dichotomized 4-point Likert scale: (strongly agree + agree) vs. (disagree + strongly disagree)