Economic evaluation of a Decision Support Tool to guide intensity of mental health care in general practice: the Link-me pragmatic randomised controlled trial

Table 2 Societal costs, including intervention costs, according to trial arm, in total sample and stratified by prognostic group

	All participants	p value	Minimal/mild	p value	Severe	p value
	All participants	p value	prognostic group	p value	prognostic group	p value
Comparison, n	837		416		421
Intervention, n	834		414		420
6 months
Mean cost (SD) [1]
Comparison	$5,575 (12,302)		$2,647 (7,373)		$8,469 (14,906)
Intervention	$6,529 (13,315)		$2,619 (7,111)		$10,383 ($16,354)
Mean difference, Coef. (95% CI)
Primary analysis [2]	$97 (-64 to 298)	0.261	$55 (-145 to 351)	0.642	$678 (-72 to 1,624)	0.08
Sensitivity analysis [3]	$109 (-64 to 333)	0.241	$78 (-99 to 369)	0.456	$443 (-159 to 1,280)	0.164
Sensitivity analysis [4]	$144 (-73 to 424)	0.213	$77 (-176 to 482)	0.615	$546 (-133 to 1,431)	0.125
Sensitivity analysis [5]	$83 (-84 to 294)	0.358	$53 (-32 to 645)	0.670	$563 (-176 to 1,489)	0.146
12 months
Mean cost (SD) [1]
Comparison	$11,022 (21,538)		$4,749 (11,190)		$17,221 (26,903)
Intervention	$11,553 (23,787)		$5,136 (12,390)		$17,878 (28,856)
Mean difference, Coef. (95% CI)
Primary analysis [2]	$115 (-203 to 505)	0.505	$179 (-162 to 659)	0.344	$344(-1,835 to 3,057)	0.778
Sensitivity analysis [3]	-$9 (-223 to 272)	0.946	-$93 (-234 to 125)	0.345	-$111 (-2,481 to 2,481)	0.937
Sensitivity analysis [4]	$1 (-243 to 320)	0.993	-$91 (-224 to 118)	0.336	-$24 (-2620 to 3,469)	0.998
Sensitivity analysis [5]	$100 (-228 to 502)	0.56	$177 (-159 to 652)	0.342	$105 (-2142 to 2,919)	0.934
Sensitivity analysis [6]	-$259 (-1,188 to 1,184)	0.673	-$115 (-1,029 to 2,012)	0.872	$341 (-4,420 to 7,740)	0.908

SD Standard deviation, Coef. Estimated coefficient, CI Confidence interval
[1] Estimated using multiple imputation. [2] Mean for intervention arm minus mean for comparison arm estimated using generalized linear models (gamma family, log link) adjusted for baseline K10 (all models) and prognostic group (model with all participants only). Estimated using multiple imputation. [3] Sensitivity analysis using complete cases only using generalized linear models (gamma family, log link) adjusted for baseline K10 (all models) and prognostic group (model with all participants only). [4] Same as [3] but adjusted for general practice. [5] Sensitivity analysis where care navigators spent 50% of time on care navigation. Data was multiply imputed prior to analysis. [6] Sensitivity analysis using participants with Medicare Benefits Schedule and Pharmaceutical Benefits Scheme data adding covariates of sex and holding a health care card. Only includes 466 participants providing consent to this data (n = 238 in comparison group, n = 228 in Intervention group)

ISSN: 2731-4553