Collective outbreak of severe acute histoplasmosis in immunocompetent Chinese in South America: the clinical characteristics and continuous monitoring of serum cytokines/chemokines

Table 2 General information, symptoms and signs, and imaging examinations of the 10 patients

patient No.	1	2	3	4	5	6	7	8	9	10
General information
age (year)	42	50	50	48	40	56	43	47	32	30
incubation period (day)	11	9	11	13	12	12	11	10	11	12
onset day	2019-03-27	2019-03-23	2019-03-27	2019-03-29	2019-03-29	2019-03-29	2019-03-27	2019-03-29	2019-03-29	2019-04-02
job	soil cleaner	soil cleaner	soil cleaner	soil cleaner	docker	site supervisor	flame cutter	site supervisor	docker	flame cutter
exposure time (hour)	48	36	54	96	0.2	0.3	4	0.3	0.2	2
symptoms and signs
fever	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes
chills	coma	no	yes	no	no	no	no	yes	no	no
insomnia	coma	yes	no	yes	yes	yes	no	yes	yes	yes
dizzy	coma	no	yes	yes	yes	yes	no	yes	yes	yes
headache	coma	no	yes	no	yes	no	yes	yes	yes	yes
cough	coma	yes	yes	yes	yes	yes	yes	yes	yes	yes
sputum	coma	yes	yes	no	no	yes	yes	yes	no	no
dyspnea	coma	yes	yes	yes	yes	yes	no	no	no	no
thoracodynia	coma	no	no	no	yes	no	no	no	no	no
anorexia	coma	yes	no	no	yes	no	yes	yes	yes	yes
nausea	coma	no	no	no	no	no	no	yes	no	yes
vomit	coma	no	no	no	no	no	no	yes	no	yes
diarrhea	no	no	no	no	no	no	no	yes	no	no
lung moist rales	yes	yes	no	yes	no	no	no	no	no	no
rash	yes	no	no	yes	no	no	no	no	yes	no
imaging findings
multiple nodular shadows in chests	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes
consolidation shadows in chests	yes	yes	no	no	no	no	no	no	no	no
ground-glass opacity shadows in chests	yes	yes	no	yes	yes	yes	yes	yes	yes	yes
mediastinum and/or hilar lymphadenopathy	yes	yes	yes	yes	yes	yes	yes	yes	yes	yes
pleural effusion	yes	no	no	no	yes	yes	no	no	no	yes
pericardial effusion	yes	no	no	yes	no	yes	no	no	no	no
meningeal thickening	yes	no	no	no	no	no	no	no	no	no
hepatomegaly	no	no	no	no	yes	no	no	no	no	no
splenomegaly	no	yes	yes	yes	yes	yes	no	yes	yes	yes

ISSN: 2731-4553