Table 2 Trends in comorbidities in patients with depression in Flanders, Belgium (2000-2019)
From: Trends in the epidemiology of depression and comorbidities from 2000 to 2019 in Belgium
Variables | 2000-2003 | 2004-2007 | 2008-2011 | 2012-2016 | 2017-2019 | Trend test | ||
|---|---|---|---|---|---|---|---|---|
STUDY POPULATION | ||||||||
Patients with depression (n) | 3268 | 3650 | 3535 | 3545 | 5732 | 0 | ||
Mean age (standard deviation) | 45.2(17) | 45.4(17.1) | 44.9(17) | 44.3(17.5) | 44.5(18.6) | 1 | ||
Number of women (%) | 2054(62.9) | 2392(65.5) | 2244(63.5) | 2189(61.7) | 3720(64.9) | 0.6175 | ||
PREVALENCE OF COMORBIDITIES, n (%) | ICPC code | |||||||
Mean chronic disease count per patient (SD) | 1.2(1.6) | 1.3(1.8) | 1.5(2) | 1.6(2) | 1.8(2.1) | 0.0002 | ||
Anxiety disorder | P74 | 15(0.5) | 26(0.7) | 28(0.8) | 31(0.9) | 167(2.9) | <0.0001 | |
Alcohol abuse | P15-16 | 60(1.8) | 98(2.7) | 98(2.8) | 163(4.6) | 208(3.6) | <0.0001 | |
Dementia | P70 | 15(0.5) | 15(0.4) | 30(0.8) | 41(1.2) | 63(1.1) | <0.0001 | |
Schizophrenia | P72 | 13(0.4) | 15(0.4) | 13(0.4) | 16(0.5) | 28(0.5) | 0.4464 | |
Suicide/suicide attempt | P77 | 3(0.1) | 6(0.2) | 7(0.2) | 9(0.3) | 34(0.6) | <0.0001 | |
Phobia/compulsive disorder | P79 | 29(0.9) | 25(0.7) | 23(0.7) | 46(1.3) | 76(1.3) | 0.0012 | |
Personality disorder | P80 | 10(0.3) | 26(0.7) | 30(0.8) | 52(1.5) | 194(3.4) | <0.0001 | |
Anorexia nervosa/bulimia | P86 | 5(0.2) | 1(0) | 3(0.1) | 5(0.1) | 12(0.2) | 0 | |
Substance abuse | P18-19 | 7(0.2) | 10(0.3) | 17(0.5) | 16(0.5) | 65(1.1) | <0.0001 | |
Atrial fibrillation/flutter | K78 | 47(1.4) | 50(1.4) | 54(1.5) | 69(1.9) | 128(2.2) | 0.0004 | |
Hypertension | K86-87 | 392(12) | 486(13.3) | 492(13.9) | 429(12.1) | 836(14.6) | 0.0074 | |
Heart failure | K77 | 23(0.7) | 35(1) | 30(0.8) | 32(0.9) | 46(0.8) | 0.8971 | |
Atherosclerosis | K92 | 59(1.8) | 82(2.2) | 62(1.8) | 61(1.7) | 88(1.5) | 0.0707 | |
Ischemic heart disease | K74-75-76 | 95(2.9) | 126(3.5) | 98(2.8) | 103(2.9) | 140(2.4) | 0.039 | |
Diabetes Mellitus | T89-90 | 114(3.5) | 167(4.6) | 231(6.5) | 320(9) | 382(6.7) | <0.0001 | |
Hypothyroidism | T86 | 50(1.5) | 47(1.3) | 49(1.4) | 57(1.6) | 162(2.8) | <0.0001 | |
Hyperthyroidism | T85 | 6(0.2) | 12(0.3) | 6(0.2) | 7(0.2) | 31(0.5) | 0.0093 | |
Irritable bowel syndrome | D01-D93 | 296(9.1) | 363(9.9) | 378(10.7) | 363(10.2) | 549(9.6) | 0.6288 | |
Asthma | R96 | 194(5.9) | 277(7.6) | 321(9.1) | 348(9.8) | 603(10.5) | <0.0001 | |
COPD | R95 | 83(2.5) | 110(3) | 104(2.9) | 94(2.7) | 214(3.7) | 0.0055 | |
Osteoarthritis | L89-90-91 | 314(9.6) | 384(10.5) | 434(12.3) | 356(10) | 528(9.2) | 0.1349 | |
Cerebrovascular disease | K90-91 | 60(1.8) | 68(1.9) | 72(2) | 78(2.2) | 153(2.7) | 0.0025 | |
Malignancy | A79-Y78-N74-Y77-U76-T71-D76-D74-U77-U75-D75-R84-B74-S77-R85-D77-X76-W72-X75-X77 | 97(3) | 139(3.8) | 194(5.5) | 259(7.3) | 696(12.1) | <0.0001 | |
Chronic Kidney Disease | 44(1.3) | 35(1) | 36(1) | 36(1) | 66(1.2) | 0.7067 | ||