Table 3 Deterministic analysis of cost savings comparing Alpha-Stim AID CES (n = 47) versus usual care (n = 47) following pathways in Fig. 1
Expected | Lower | Upper | Expected | Lower | Upper | Expected | Lower | Upper | ICER | Cost Saving Probability | Cost -Effectiveness Probability (WTP threshold £25,000 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cost | 95% CI | 95% CI | Responses | 95% CI | 95% CI | QALYs | 95% CI | 95% CI | |||||
AlphaStim against usual care with Standard Practice iCBT (8 60 min sessions) | Control | £438,617 | £366,723 | £521,275 | 872.27 | 841.66 | 900.59 | 123.78 | 79.31 | 180.12 | -£ 23,821.73 | 100% | 66% |
AlphaStim | £199,253 | £150,479 | £262,493 | 921.60 | 903.61 | 935.62 | 130.89 | 73.84 | 216.06 | ||||
Net | -£239,364 | -£313,382 | -£167,971 | 49.33 | 24.28 | 77.07 | 7.11 | −5.47 | 35.94 | ||||
AlphaStim against usual care with Clark and Wells Model iCBT (14 90 min sessions) | Control | £963,334 | £789,707 | £1,150,329 | 872.27 | 841.97 | 899.79 | 123.78 | 77.44 | 180.99 | -£ 68,138.61 | 100% | 75% |
AlphaStim | £342,155 | £237,463 | £467,168 | 921.60 | 904.06 | 935.73 | 130.89 | 71.85 | 216.30 | ||||
Net | -£621,179 | -£803,823 | -£455,179 | 49.33 | 23.90 | 78.58 | 7.11 | −5.59 | 35.31 | ||||
AlphaStim against usual care with Heimberg Model iCBT (15 60 min sessions plus one 90 min session) | Control | £781,701 | £648,113 | £932,532 | 872.27 | 843.36 | 901.03 | 123.78 | 77.71 | 183.35 | -£ 52, 975.2 | 100% | 74% |
AlphaStim | £292,689 | £209,114 | £401,075 | 921.60 | 902.55 | 935.13 | 130.89 | 73.87 | 209.88 | ||||
Net | -£489,012 | -£625,683 | -£356,973 | 49.33 | 21.96 | 78.84 | 7.11 | −3.84 | 26.54 |