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Table 2 Factors associated with the use of a CRP test in relation to antibiotic prescribing

From: Factors associated with C-reactive protein testing when prescribing antibiotics in general practice: a register-based study

 

Model 1

Model 2

Number (%) prescription with CRP test

Multivariable model for the four types of antibiotics recommended for RTIs

Number (%) prescription with CRP test

Multivariable model for the four types of antibiotics recommended for RTIs with RTI as stated indication

N = 984,149

N = 487,939

Patient characteristics

n (%)

OR (95% CI)

n (%)

OR (95% CI)

Overall

335,755 (34.1)

220,733 (45.2)

Male

142,507 (33.3)

1

91,759 (45.2)

1

Female

193,248 (34.7)

1.05 (1.04–1.06)

128,974 (45.3)

1.00 (0.98–1.01)

18–44

125,436 (33.2)

1

87,038 (42.6)

1

45–64

108,825 (34.6)

1.02 (1.00–1.03)

69,245 (47.7)

1.19 (1.17–1.22)

65–74

58,595 (37.3)

1.05 (1.01–1.08)

37,339 (51.1)

1.30 (1.24–1.35)

75+

42,899 (31.7)

0.82 (0.79–0.86)

27,111 (41.5)

0.91 (0.86–0.96)

Education <10 years

67,899 (33.1)

1

44,292 (43.3)

1

Education 10–15 years

195,632 (34.4)

1.05 (1.03–1.07)

128,464 (45.6)

1.10 (1.08–1.12)

Education >15 years

72,224 (34.4)

1.04 (1.02–1.07)

47,977 (46.1)

1.13 (1.10–1.17)

Working

185,237 (34.6)

1

124,386 (45.2)

1

Pension

100,956 (34.7)

1.00 (0.98–1.03)

64,294 (46.6)

1.01 (0.97–1.05)

Out of workforce or disability pension

49,562 (31.3)

0.84 (0.83–0.85)

32,053 (43.0)

0.90 (0.88–0.92)

Single

165,734 (32.8)

1

109,632 (43.5)

1

Married/Partner

170,021 (35.5)

1.08 (1.07–1.10)

111,101 (47.1)

1.07 (1.05–1.09)

Danish

303,038 (34.4)

1

199,482 (45.5)

1

Immigrant

28,969 (32.2)

0.91 (0.88–0.95)

18,763 (43.4)

0.92 (0.89–0.96)

Descendant of immigrants

3748 (31.0)

0.90 (0.84–0.96)

2488 (40.5)

0.91 (0.84–0.98)

Clinical characteristics

 Charlson 0

274,552 (34.0)

1

180,384 (45.5)

1

 Charlson 1

28,911 (36.6)

1.07 (1.05–1.09)

19,668 (44.7)

0.92 (0.90–0.95)

 Charlson >1

32,292 (32.7)

0.93 (0.91–0.95)

20,681 (43.3)

0.87 (0.84–0.90)

 No chronic conditions

274,124 (33.3)

1

180,549 (44.1)

1

 Chronic conditionsa

61,631 (38.6)

1.22 (1.18–1.26)

40,184 (51.2)

1.24 (1.19–1.29)

 0 contacts previous year

36,709 (31.4)

1

24,175 (42.0)

1

 1–4 contacts previous year

162,103 (33.2)

0.99 (0.98–1.01)

107,685 (44.0)

1.03 (1.01–1.05)

  > 4 contacts previous year

136,943 (36.1)

1.03 (1.00–1.05)

88,873 (47.8)

1.13 (1.10–1.17)

 0 antibiotic treatments previous year

253,058 (34.3)

1

165,331 (46.3)

1

 1 antibiotic treatment previous year

61,385 (34.2)

0.91 (0.90–0.93)

40,834 (43.7)

0.83 (0.82–0.85)

  > 1 antibiotic treatment previous year

21,312 (31.6)

0.75 (0.73–0.77)

14,568 (39.2)

0.64 (0.62–0.66)

 0 CRP previous year

222,657 (31.7)

1

146,070 (43.2)

1

 1 CRP previous year

70,752 (38.1)

1.33 (1.30–1.36)

46,585 (48.3)

1.23 (1.20–1.27)

  > 1 CRP previous year

42,346 (44.2)

1.78 (1.73–1.84)

28,078 (53.0)

1.58 (1.52–1.64)

 October–March

210,163 (37.4)

1

141,915 (46.0)

1

 April–September

125,592 (29.8)

0.71 (0.70–0.72)

78,818 (44.0)

0.93 (0.92–0.95)

  1. a Defined by patient being followed in practice with at least one chronic condition in the previous year