Table 1 Interview guide main questions

1. Polypharmacy in everyday practice (Icebreaker)

Which role do polypharmacy patients play in your daily practice?

2. Using the eCRF

You have entered [number of] patients, what experiences did you have with the eCRF?

3. General overview of the CMR

What are your experiences with the PRIMA-eDS CMR?

4. Output of the CMR and how GPs responded to the recommendations

Going through the CMR of one of the GP’s patient

What do you think about the various sections?

What happens between reading the recommendations and the moment of discontinuing medication?

How did the CMR influence you in treating your patients?

5. Implementation of the PRIMA-eDS tool into daily practice routine

Which benefits/barriers do you see in using the PRIMA-eDS tool in the future?

Do you have any recommendations for further development?