Heart failure labelled patients with missing ejection fraction in primary care: prognosis and determinants

BMC Primary Care

Table 1 Characteristics, clinical profile, and treatment according to the ejection fraction of heart failure patients

	EF >50 n=418		EF <=50 n=297		No EF n=7661		EF>50 versus No EF	EF < =50 versus No EF
	n	%	N	%	n	%	p value	p value
Gender (women)	253	60,5	98	33,0	4331	56,5	0,109	<0.001
Age (Mean,SD)	77.1 (9.5)		74.2 (11.5)		78.3 (10.2)		0.053	<0.001
Socioeconomic deprivation index
1 (less disadvantaged)	98	23.4	60	20.2	1486	19.4
2	126	30.1	97	32.6	1377	17.9
3	102	24.4	53	17.8	1533	20.0
4	60	14.3	48	16.1	1544	20.1
5 (more disadvantaged)	29	6.9	36	12.1	1586	20.7	<0.001	<0.001
Previous hospitalization for heart failure	91	21.8	130	43.8	2792	36.4	<0.001	0,010
Patients requiring home care	64	15.3	54	18.1	2124	27.7	<0.001	<0.001
Cardiovascular risk factors
Hypertension	328	78.4	214	72.0	5823	76.0	0,250	0,118
Diabetes	129	30.8	108	36.3	2528	33.0	0,365	0,227
Hypercholesterolemia	145	34.6	97	32.6	2241	29.2	0,018	0,206
Obesity	71	16.9	42	14.1	1742	22.7	0,006	<0.001
Smoking habit	26	6.2	33	11.1	619	8.0	0,380	<0.001
Cardiovascular disease
Coronary heart disease	94	22.4	127	42.7	2009	26.2	0,090	0,000
Atrial fibrillation	150	35.8	98	33.0	2794	36.4	0,809	0,222
Stroke	37	8.8	30	10.1	770	10.0	0,426	0,978
Peripheral artery disease	26	6.2	24	8.0	463	6.0	0,883	0,151
COPD	65	15.5	49	16.50	1240	16.19	0,731	0,886
Chronic renal failure	83	19.8	53	17.85	1397	18.24	0,404	0,864
Drug therapy
ACE inhibitor or ARB	305	73.0	254	85.5	5736	74.9	0,382	<0.001
Beta-blocker	212	50.7	205	69.0	3729	48.7	0,416	<0.001
Loop diuretics	246	58.8	212	71.38	5889	76.8	<0.001	0,028
Outcomes
Hospitalization	50	11,96	57	19,1	2157	28,1	0,000	0,001
Mortality	30	7,18	33	11,1	1545	20,1	0,000	0,000

EF Ejection Fraction, SD Standard deviation, COPD Chronic obstructive pulmonary disease, ACE angiotensin converting enzyme, ARB Angiotensin Receptor Blocker

ISSN: 2731-4553