Table 3 Patient demographics and independent variables

Mean Age ± SD (range) years

45 ± 13 (18 to 70)

1.00 (0 .99 to 1.01)

0.85

Male (%)

884 (33.2)

1

Female (%)

1778 (66.8)

1.03 (0.86 to 1.23)

0.734

  SIMD quintile 1(least deprived)

248 (9.3)

1

  SIMD quintile 2

322 (12.1)

1.17 (0.80 to 1.72)

0.41

  SIMD quintile 3

167 (6.3)

1.67 (1.08 to 2.58)

0.021

  SIMD quintile 4

522 (19.6)

1.38 (0.98 to 1.94)

0.068

  SIMD quintile 5 (most deprived)

1364 (51.2)

1.55 (1.11 to 2.16)

0.009

  SIMD unknown (not in model)

39 (1.5)

  0

1728 (64.9)

1

  1

665 (25.0)

1.10 (0.90 to 1.33)

0.356

  ≥2

269 (10.1)

1.18 (0.90 to 1.54)

0.238

  Non-smoker

1581 (59.4)

1

  Smoker

1050 (39.4)

1.13 (0.95 to 1.34)

0.165

  Smoking status unknown (not in model)

31 (1.2)

  ADM for <2 y (%)

1909 (71.7)

1

  Same ADM for ≥2 y

753 (28.3)

1.80 (1.49 to 2.17)

<0.001

  1

82 (2.2)

1

  2

265 (2.7)

1.98 (1.09 to 3.57)

0.024

  3

242 (3.6)

1.26 (0.68 to 2.35)

0.461

  4

191 (4.4)

3.26 (1.77 to 5.99)

<0.001

  5

372 (6.5)

1.50 (0.84 to 2.69)

0.171

  6

201 (5.9)

2.69 (1.47 to 4.94)

0.001

  7

224 (5.7)

2.20 (1.21 to 4.01)

0.01

  8

322 (6.4)

1.81 (1.01 to 3.24)

0.047

  9

181 (5.8)

3.80 (2.06 to 7.01)

<0.001

  10

302 (8.0)

2.32 (1.29 to 4.18)

0.005

  11

280 (9.3)

3.54 (1.96 to 6.38)

<0.001