|
Mean Age ± SD (range) years
|
45 ± 13 (18 to 70)
|
1.00 (0 .99 to 1.01)
|
0.85
|
|
Male (%)
|
884 (33.2)
|
1
| |
|
Female (%)
|
1778 (66.8)
|
1.03 (0.86 to 1.23)
|
0.734
|
|
Deprivation (%)
|
|
SIMD quintile 1(least deprived)
|
248 (9.3)
|
1
| |
|
SIMD quintile 2
|
322 (12.1)
|
1.17 (0.80 to 1.72)
|
0.41
|
|
SIMD quintile 3
|
167 (6.3)
|
1.67 (1.08 to 2.58)
|
0.021
|
|
SIMD quintile 4
|
522 (19.6)
|
1.38 (0.98 to 1.94)
|
0.068
|
|
SIMD quintile 5 (most deprived)
|
1364 (51.2)
|
1.55 (1.11 to 2.16)
|
0.009
|
|
SIMD unknown (not in model)
|
39 (1.5)
| | |
|
†Co-morbidities (%)
|
|
0
|
1728 (64.9)
|
1
| |
|
1
|
665 (25.0)
|
1.10 (0.90 to 1.33)
|
0.356
|
|
≥2
|
269 (10.1)
|
1.18 (0.90 to 1.54)
|
0.238
|
|
Current Smoking Status (%)
|
|
Non-smoker
|
1581 (59.4)
|
1
| |
|
Smoker
|
1050 (39.4)
|
1.13 (0.95 to 1.34)
|
0.165
|
|
Smoking status unknown (not in model)
|
31 (1.2)
| | |
|
SSRI use (%)
|
|
ADM for <2 y (%)
|
1909 (71.7)
|
1
| |
|
Same ADM for ≥2 y
|
753 (28.3)
|
1.80 (1.49 to 2.17)
|
<0.001
|
|
Practice (% practice pop.)
|
|
1
|
82 (2.2)
|
1
| |
|
2
|
265 (2.7)
|
1.98 (1.09 to 3.57)
|
0.024
|
|
3
|
242 (3.6)
|
1.26 (0.68 to 2.35)
|
0.461
|
|
4
|
191 (4.4)
|
3.26 (1.77 to 5.99)
|
<0.001
|
|
5
|
372 (6.5)
|
1.50 (0.84 to 2.69)
|
0.171
|
|
6
|
201 (5.9)
|
2.69 (1.47 to 4.94)
|
0.001
|
|
7
|
224 (5.7)
|
2.20 (1.21 to 4.01)
|
0.01
|
|
8
|
322 (6.4)
|
1.81 (1.01 to 3.24)
|
0.047
|
|
9
|
181 (5.8)
|
3.80 (2.06 to 7.01)
|
<0.001
|
|
10
|
302 (8.0)
|
2.32 (1.29 to 4.18)
|
0.005
|
|
11
|
280 (9.3)
|
3.54 (1.96 to 6.38)
|
<0.001
|
