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Table 4 Diagnostic accuracy of PSA levels ≥ 4 ng/ml stratified by age

From: Prostate-specific antigen testing accuracy in community practice

Age

Sensitivity (%)

Specificity (%)

LR + (95% CI)

LR – (95% CI)

40 – 49

75

55

1.68 (1.17, 2.40)

0.45 (0.21, 0.95)

50 – 59

80

40

1.34 (1.19, 1.52)

0.49 (0.34, 0.71)

60 – 69

84

32

1.24 (1.16, 1.32)

0.50 (0.39, 0.64)

≥ 70

90

27

1.23 (1.16, 1.32)

0.37 (0.27, 0.51)

  1. Abbreviations: PSA = prostate-specific antigen. LR+ = likelihood ratio for a positive test. LR- = likelihood ratio for a negative test. CI = confidence interval.