From: Challenges in diagnostic accuracy studies in primary care: the fecal calprotectin example
Red flag symptom | Measurement | Positive |
---|---|---|
Growth failure | Growth calculator | Height for age < -1 SDS |
Involuntary weight loss | History | Involuntary decrease in weight |
Rectal blood loss | History | Rectal blood loss with defecation |
Positive family history of inflammatory bowel disease | History | First-degree relatives |
Extra-intestinal symptoms | Physical examination | Eyes (episcleritis, scleritis, uveitis), skin (erythema nodosum, pyoderma gangrenosum, psoriasis), mouth ulcers, finger clubbing, arthritis |
Peri-anal lesions | Physical examination | Skin tags, hemorrhoids, fissures, fistulas, abscess |
Anemia (Hb) | Hematology | 4-12 years < 7.1 mmol/l, |
boy 12-18 years <8.1 mmol/l, | ||
girl 12-18 years <7.4 mmol/l [22] | ||
CRP | Chemistry | > 10 mg/l [23] |
ESR | Hematology | |
Platelets | Hematology | > 450 x 109 /l [24] |