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Table 3 Sensitivity and specificity of 'Unexpected genital bleeding' according to cancer diagnosis, with corresponding positive predictive values of cervical and uterine cancer

From: Symptoms and signs of urogenital cancer in primary care

 

N

Sensitivity (A)

Specificity

 

PPV

 

Sensitivity (B)

Females

All

95% CI

 

95% CI

All

95% CI

All

95% CI

Cervical cancer

10

        

'Unexpected genital bleeding' and cancer (A):

1

10.0%

8.6–28,6

  

 < 0.1%

   

'Unexpected genital bleeding' and cancer (B):

2

      

20.0%

4.8–44.8

'Unexpected genital bleeding, without cancer: 195 patients

 No 'Unexpected genital bleeding, no cancer: 60,967 patients

   

99.7%

99.6–99.7

    

 Uterine body cancer

14

        

 'Unexpected genital bleeding' and cancer (A):

3

21.4%

 < 0.1–42.9

  

1.5%

0.2–3.1

  

 'Unexpected genital bleeding' and cancer (B):

10

      

71.4%

47.8–95.1

  1. A: Sensitivity, specificity and PPV based on consultation recordings
  2. B: Sensitivity based on all recordings from consultation to diagnosis