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Table 1 Data extraction table

From: Workload and workflow implications associated with the use of electronic clinical decision support tools used by health professionals in general practice: a scoping review

Authors

Origin

Aims

Context

Methods

Outcome measures

Key findings of interest

Impact on time/workload

Ahmad et al. 2010 [26]

Canada

To enhance understanding about computer-assisted health-risk assessments (HRA) from physicians’ perspectives regarding benefits and concerns/challenges

Condition of focus: Domestic violence

Setting: 1 family practice clinic

Tool: Health Risk Assessment tool

- Embedded/linked with EMR: Yes

- Interruptive alert: No, guides visit

- User-driven: Physician

- Risk score: No

Qualitative interviews

(1) What do you think of your experience with the HRA?

(2) How would you describe its potential across various risks and visits?

(3) Would you recommend such HRA in a family practice setting?

4) What factors are important for its implementation in a family practice setting?

Theme 2: perceived risks & challenges (subtheme: length of visit)

- Some expressed concern about the increase in length of the visit

- Others managed the time pressure by offering follow-up visits or viewed the task of risk review as a professional obligation even if it meant increases in the consultation time

- Follow-up visit offered in order to avoid “taking time away” from other waiting patients

- ‘Patient readiness'—not always the right time to address in the visit

Perception

Impact on time: Mixed views

Arts et al. 2017 [27]

Netherlands

To investigate the effectiveness of a CDSS as measured by GPs' adherence to the Dutch GP guideline for patients with Atrial Fibrilation

Condition of focus: Stroke prevention in AF

Setting: General Practice

Tool: CDS using antithrombotic guidelines

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Physician

- Risk score: Yes

Quantitative RCT

Primary: Difference in the proportion of patients with AF treated in accordance with the guideline between the intervention and control groups

Secondary: reasons GPs provided for deviating from the guideline and how they responded to required justification

Limited evidence for effectiveness, attributed to low usage

Reasons for low usage discussed in a separate qualitative evaluation, but included barriers relating to lack of time, too many alert notifications and tool functionality limitations

Perception

Impact on time: Increase

Driving perception: lack of time, too many alerts

Arts et al. 2018 [28]

Netherlands

To identify remediable barriers which led to low usage rates seen in RCT

Condition of focus: Stroke prevention in AF

Setting: General Practice

Tool: CDS using antithrombotic guidelines

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Physician

- Risk score: Yes

Mixed: quantitative survey + focus group

Barriers and facilitators for CDSS use

More than 75% of GPs answered the question: "What were the most important reasons for not opening the recommendations?" citing reasons relating to lack of time

Many felt there was lack of time during the appointment to perform the suggested actions. Some GPs scheduled follow up appointments for this purpose

Perception

Impact on time: Increase

Baron et al. 2017 [29]

USA

To evaluate the value and feasibility of three examples of CDS relating to occupational health in five primary care group practices

Condition of focus: Occupational Health

Setting: Primary Care

Tool: CDS using guidelines

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: Physician

- Risk score: No

Qualitative:- interviews + observations

Interviews:

- physicians' daily work patterns

- experience with EMRs and CDS

- attitudes and practice regarding consideration of health factors encountered in a patient’s job

- how patients' work data is collected in the EMR

Observations:

- workflow data through observations of clinic staff

The amount of clinical time the CDS tools would require was a prominent concern

1 of 7 themes: clinician acceptance is affected by whether CDS adds or saves time

Perception

Impact on time: No conclusion

Bauer et al. 2014 [30]

USA

To examine the

attitudes and opinions of paediatric users’ toward the Child Health Improvement through Computer Automation (CHICA) system

Condition of focus: Child Health

Setting: Community paediatric clinics

Tool: Child Health Improvement (CHICA) CDS for paediatric visits

- Embedded/linked with EMR: Yes

- Interruptive alert: No, guides visit

- User-driven: Physician & patient

- Risk score: No

Quantitative: survey + free text

General acceptability and satisfaction

Critical opinions of CHICA were that it wasted time and money. This perception persisted in spite of informal time-flow studies in one of the clinics showing that CHICA did not create significant delays

Approximately half of respondents reported that it did slow down clinic

Perception and objective measure showed conflict

Impact on time: Increase (perception), no impact (objective)

Driving perception: lack of time, workflow disruption

Carlfjord et al. 2011 [31]

Sweden

To explore how staff at 6 Primary Health Care units experienced implementation of a tool for lifestyle intervention in primary health care

Condition of focus: Preventive care

Setting: PHC units

Tool: CDS for lifestyle intervention & preventive services

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: Patient-completed

- Risk score: Unclear

Qualitative: focus groups + interviews

- Overall working situation coinciding with the implementation process

- Experiences of implementation activities and the tool

- How to address lifestyle issues with patients

- Openness to innovations

GPs' perception of workload already being too heavy and accommodating never-ending changes such as the lifestyle intervention tool may threaten independence and bring extra work

Perception

Impact on time: Increase

Driving perception: workload already heavy

Carlfjord et al. 2012 [32]

Sweden

Qualitative evaluation of the 2011 study to explore staff’s perceptions of handling lifestyle issues, including the consultation as well as the perceived usefulness of the tool

Condition of focus: Preventive care

Setting: PHC units

Tool: CDS for lifestyle intervention & preventive services

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: Patient-completed

- Risk score: Unclear

Qualitative: focus groups

Staff responses to two scenarios:

- How to handle the patient/consultation

- Advice to give to another clinic considering implementing the tool

Lifestyle issues tend to be forgotten when the workload is increasing, despite interest and awareness of its importance

Many staff members found it difficult to initiate a conversation about lifestyle, particularly alcohol consumption, when the patient is seeking care for something else

Time is too pressured to be focused on lifestyle/prevention especially in acute times/low resources

Perception

Impact on time: Increase

Driving perception: no time for preventive care

Chiang et al. 2017 [33]

Australia

To test the acceptability and feasibility of the Treat to Target CVD (T3CVD), an EMR-based CDS tool, for the evaluation of Absolute CVD Risk in general practice

Condition of focus: Cardiovascular Disease

Setting: 1 general practice

Tool: CDS for CVD risk assessment

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Automatic, based on EMR data

- Risk score: Yes, for patients with > 10% risk of CVD

Qualitative interviews

Acceptability and feasibility of the T3CVD tool, including GPs’ experiences with the tool in real-world clinical practice, under a framework of 3 themes:

- patient control

- clinical quality of care

- technology capability/capacity

GPs described how the ACVDR assessment pop-up necessitated additional time, often needing to arrange a follow-up visit if there was no time to discuss

While the tool had capacity to save time by automating information provision rather than GPs manually accessing the existing CVD risk tool, it is potentially disruptive and adds to many existing pop-ups

Perception

Impact on time: Mixed views

Chiang et al. 2015 [15]

Australia

To explore the use of a cancer risk tool, which implements the QCancer model, in consultations and its potential impact on clinical decision making

Condition of focus: Cancer

Setting: General Practice

Tool: QCancer risk tool

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: GP

- Risk score: Yes, for each of 10 cancers

Qualitative: simulated consultations + interviews

1. Coherence

2. Cognitive participation

3. Collective action

4. Reflexive monitoring

Tool was easy and quick to use, but introducing the emotive topic of cancer caused anxiety. Risk output 'too confronting' to use in a consultation and could lead to a loss of control over the consultation and time being used to reassure which may lead to overrunning by 20-30 m

GPs thought pop-up alerts would add to alert fatigue

Perception

Impact on time: Increase

Driving perception: impact on conversation

Crawford et al. 2011 [34]

Scotland

To understand primary care practitioners’ views towards screening for diabetic foot disease and their experience of the SCI-DC system

Condition of focus: Diabetic foot disease

Setting: General Practice

Tool: CDS for screening

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: GP

- Risk score: Unclear

Qualitative interviews

Views on and use of decision support systems, specifically SCI-DC

The duplication of effort to complete the SCI-DC and then the GP IT system through which the practice receives remuneration is unnecessarily time consuming. Integration into GP IT systems is central to its adoption

Perception

Impact on time: Increase

Driving perception: stand-along system, double data entry needed

Curry et al. 2011 [35]

Canada

To explore two issues in the implementation of

CDS for Diagnostic Imaging:

- Will physicians incorporate decision-support technology into their clinical routines?

- Will physicians follow clinical advice when

Provided?

Condition of focus: Diagnostic imaging

Setting: Family Medicine clinic

Tool: CDS to guide decisions to order imaging

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: GP

- Risk score: No

Mixed: quantitative analysis of useage data + qualitative interviews

Quantitative—usage by clinicians

Qualitative—perceived effects of taking part in the study and challenges

The largest challenge was perceived interference with usual work flows, specifically the interactivity between EMR and the CDS (perceived to be too slow, although measured as less than 1 s). The time for physicians to interact with CDS was also perceived to be too long

Time taken to use tool (described in Methods) 2 min 15 s as follows:

- 1 min to enter data, 5 s for CDS to check if appropriate

- < 1 min for clinician to look at recommendation if not appropriate

- 10 s to complete DI order if still required

Perception and objective measure of time to use tool showed conflict

Impact on time: Increase

Driving perception: slow software, workflow disruption

Dikomitis et al. 2015 [36]

UK

To collect data on the (non)use of electronic risk assessment tools (eRATs) and on the experiences of using the tool in everyday practice

Condition of focus: Cancer

Setting: General Practice

Tool: eRATs

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: GP

- Risk score: Yes

Qualitative interviews

Normalisation Process Model:

(1) interactional workability

(2) relational integration

(3) skill-set workability

(4) contextual integration

Interactional workability—GPs' reactions to the on-screen prompts was influenced by different factors:

- the approach of the doctor

- the GP’s clinical experience

- time pressures in specific consultations

Contextual integration—most issues related generally to new interventions being implemented:

- GPs expected to multi-task within one consultation

- constant time pressures

- prompt fatigue is a risk if added to an already 'busy screen' and alerts may not be responded to

- concern over workload for secondary care

Perception

Impact on time: Increase

Driving perception: lack of time

Duyver et al. 2010 [37]

Belgium

To explore GPs' perceptions of feasibility and added value of the MDS-HC as a geriatric assessment tool and to investigate potential barriers and facilitating factors regarding the implementation of this

tool in an ambulatory community setting

Condition of focus: Geriatric care

Setting: General Practice

Tool: Home care assessment tool

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: GP

- Risk score: No

Quantitative: survey + free text

Four assessment areas:

(1) technical acceptability

(2) clinical relevance of the tool

(3) management and optimization of health care planning

(4) valorisation of the role of the GP

Free comments from GPs:

- Long and fastidious encoding

- CDS was too long, added admin workload

- Excellent concept, worth making easier and shorter to use

Perception

Impact on time: Increase

Driving perception: slow software

Eaton et al. 2012 [38]

USA

To examine Abdominal Aortic Anneurysm (AAA)

screening ordering in an academic primary care internal medicine clinic that uses physician reminders based on real-time CDS for preventive screening and to identify why screening ordering rates vary among providers

Condition of focus: Abdominal Aortic Aneurysm (AAA)

Setting: Primary Care clinic

Tool: CDS for AAA screening

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: GP

- Risk score: No

Quantitative: records review

Features of the first visit during the study:

- visit date

- visit type (general medical examination vs. other type)

- provider role (staff physician vs. other)

- provider gender

- was AAA screening ultrasound was ordered during the visit

Visit time (based on the fixed length of different visit types) is an important determinant for preventive screening

Patients more likely to have screening ultrasound ordered during longer medical examinations, which usually has more time allotted (40 min) and often has a disease-prevention component

During longer medical examinations, 24% of eligible patients had the recommended AAA screening ordered, compared with only 6% during shorter visits

Objective measure of time for whole consultations (via proxy of visit type)

Impact on time: Increase

Laforest et al. 2019 [39]

UK

To review the tools available, clinician attitudes and experiences, and the effects on patients

of genetic cancer risk assessment in general

practice

Condition of focus: Cancer

Setting: General Practice

Tool: range of risk assessment tools, including web-based, risk-stratification, and paper-based

- Embedded/linked with EMR: Range

- Interruptive alert: Range

- User-driven: GP

- Risk score: Range

Systematic review

1. What tests/tools are available to identify increased genetic risk of cancer in general practice?

2. What are clinicians’ attitudes towards

Screening/testing population groups for genetic cancer risk?

3. What are the levels of patient knowledge, satisfaction, and anxiety in relation to tests and communication by a GP about cancer risk?

4. What are patients’ risk perceptions

following screening/testing for genetic

cancer risk in primary care?

5. What are the outcomes of referrals

following genetic cancer risk identification in general practice?

5 studies examined GP attitudes:

- Owens et al. (43): some providers concerned over the time needed to counsel patients who were newly determined as at high risk, and regarding liability for not successfully providing risk counselling

- Wu et al. (45): physicians at two primary care clinics felt they were already collecting high-quality family

histories and that the tool would negatively impact their workflow. Physicians believed that patients would redirect discussions away from physician priorities and, instead, focus on tool recommendations. However, post-implementation, 86% of physicians found the tool improved their practice, and none reported adverse effects on workflow

GPs were worried about the impact of risk assessment on patient anxiety, particularly if discussions with whole families would be required. GPs were concerned about their ability to explain risk and implications in short, routine appointments

Perception

Impact on time: Mixed views

Fathima et al. 2014 [40]

Australia

To systematically review

randomized controlled trials evaluating effectiveness of CDS in the care of people with asthma and COPD and to identify the key features of those systems that have the potential to overcome health system barriers and improve outcomes

Condition of focus: Asthma & COPD

Setting: Primary care

Tool: range of CDS systems, including prevention & management, providing guidelines

- Embedded/linked with EMR: Range

- Interruptive alert: Range

- User-driven: Clinician

- Risk score: No

Systematic Review (qualitative syntheses)

Assessment of intervention effects

1. Type of CDS intervention

2. Effectiveness of CDS:

- Clinical outcomes

- Healthcare process measures

- User workload and efficiency outcomes

- Relationship-centred outcomes

- Economic outcomes

- Use and Implementation outcomes

Workload and efficiency outcomes assessed included asthma documentation by ED doctors, consultation time, time for disposition decision in the ED, and user knowledge

These were assessed as the primary outcome by two trials, of which one trial showed significant improvement in rate of asthma documentation. The other trial did not show any effect from the use of CDS on the time taken to make a disposition decision

83% of studies of CDS tools which were stand-alone in design had favourable clinical outcomes, compared with 38% of embedded designs. This may be due to alert fatigue and too low a threshold for alerts being generated

Low evidence provided by studies re user workload & efficiency. One RCT in a hospital ED measured consultation time as a marker of workflow efficiency, finding no significant difference in consultation time between the intervention group compared with control

Objective measure of time for whole consultations (1 study in a systematic review)

Impact on time: neither increase nor decrease

Finkelstein et al. 2017 [41]

USA

To implement a comprehensive informatics framework to promote breast cancer risk assessment and chemoprevention in primary care that was informed by potential user feedback (usability testing to determine barriers and facilitators affecting the toolbox use by providers)

Condition of focus: Cancer

Setting: Primary care

Tool: Breast cancer risk assessment & chemoprevention

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: Clinician & patient

- Risk score: Yes

Qualitative interviews

Ease of use, content, navigation

Ease of use: notifications were noted to be too time consuming to process

Perception

Impact on time: Increase

Driving perception: Lack of time

Fox et al. 2014 [42]

USA

To evaluate adherence to an evidence-based Chronic Kidney Disease computer decision-support checklist in patients treated by Primary Care Physicians compared with usual care at a single site

Condition of focus: Chronic Kidney Disease

Setting: Primary care clinic

Tool: CDS checklists for CKD

- Embedded/linked with EMR: Unclear

- Interruptive alert: No, guides visit

- User-driven: Clinic staff

- Risk score: No

Quantitative records review

Clinical measures of CKD management

Comment that the checklist was used to create a priority and incorporated into workflow so that CKD was treated appropriately. This is a step above a simple alert at the point of care and circumvented alert fatigue

The 'extra time' needed for PCP to improve CKD care did not seem to adversely affect other areas of preventive care

Perception

Impact on time: Neither increase nor decrease

Driving perception: did not take time away from other areas of preventive care

Gill et al. 2019 [43]

USA

To examine the impact of Point Of Care CDS on diabetes management in small- to medium- sized independent primary care practices that had adopted the PCMH model of care

Condition of focus: Diabetes

Setting: Primary care practices

Tool: CDS for diabetes management

- Embedded/linked with EMR: Yes

- Interruptive alert: No, guides visit

- User-driven: Automatic

- Risk score: No

Mixed: quantitative analysis of EMR data + qualitative interviews

Quantitative: Clinical measures of diabetes management

Qualitative: Barriers to and facilitators of successful implementation of CDS that achieved optimal diabetes management

Barriers impeding implementation of the CDS included time and reimbursement in light of the need for time to implement team-based care, not specifically regarding the impact of the CDS on visit lengths

Perception

Impact on time: No conclusion

Green et al. 2015 [36, 44]

UK

To explore GPs’ experiences of incorporating Risk Assessment Tools (RATs) for lung and bowel cancers into their practice and to identify constraints and facilitators to the wider dissemination of the tools in primary care

Condition of focus: Cancer

Setting: General Practice

Tool: paper-based RATs

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: Clinician

- Risk score: Yes

Qualitative interviews

GPs' experiences of the implementation process and their use of the RATs in practice

A minority of participants did not feel RATs added to practice: "I’m not sure it fits into the consultation in a natural way of making a decision about the management of that patient. It’s one more thing to fit into a busy ten minute consultation”

Perception

Impact on time: Increase

Driving perception: workload already heavy

Gregory et al. 2017 [45, 46]

USA

To examine asynchronous alert-related workload in the EMR as a predictor of burnout in primary care providers (PCPs), in order to inform interventions targeted at reducing burnout associated with alert workload

Condition of focus: Generic

Setting: Primary care

Tool: inbox-style EMR alerts

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: Clinician

- Risk score: No

Mixed: quantitative survey + focus groups

Subjective alert workload (perception of time available to complete tasks)

Objective alert workload (actual hours spent)

Burnout (scale)

Quantitative: subjective alert workload was positively related to 2/3 dimensions of burnout. Subjective alert workload was also generally predictive of burnout, whereas objective alert workload was not

This suggest that it is the perception of alert burden that predicts burnout, rather than the actual amount of time spent attending to alerts

Qualitative: time spent managing alerts was a major theme in focus group discussion and survey comments

Perception and objective measure of workload showed conflict

Impact on workload: Mixed views

Harry et al. 2019 [47]

USA

To identify adoption barriers and facilitators before implementation of CDS for cancer prevention in primary care

Condition of focus: Cancer

Setting: Primary care clinics

Tool: CDS for cancer prevention & screening

- Embedded/linked with EMR: Yes

- Interruptive alert: No, guides visit

- User-driven: Clinician

- Risk score: Unclear

Qualitative interviews

1. Factors that facilitate or hinder key informant support for the intervention

2. Key informant knowledge and beliefs about the intervention and tension for change

3. The relative advantage(s) of the intervention compared with other interventions currently available in the EMR

4. Relevant organizational culture norms and values related to cancer prevention and screening

5. Factors that may foster adoption from a key informant perspective

6. Related external policies and incentives

7. Implementation climate

PCP time limitations were a major concern. PCPs are being asked to do more with less time, including seeing more patients in a day, making some PCPs wonder how to fit the CDS into the visit

It was perceived to be 5–10 min to use the tool, which would add time pressure as appointments are usually 'already 20 min behind'

However, some same informants who mentioned time constraints also said that this would only be a limitation until PCPs learned the CDS tools

Perception

Impact on time: Increase

Driving perception: Lack of time

Hayward et al. 2013 [48]

UK

To understand how GPs interact with prescribing CDS in order to inform deliberation on how better to support prescribing decisions in primary care

Condition of focus: Prescribing

Setting: General Practice

Tool: CDS for prescribing

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: GP

- Risk score: No

Mixed: quantitative analysis of useage data + conversation analysis

Timing of computer tasks and utterances

Prescribing alerts and responses

Conversation analysis

Total mean duration of consultation: 9 min 3 s

- time before prescribing = 5 min 47 s

- during prescribing = 1 min 47 s

- time after prescribing = 1 min 30 s

Timing of alerts was problematic as they interrupt in order to correct decisions already made rather than to assist earlier deliberations. By the time an alert appears the GP will have potentially spent several minutes considering, explaining, negotiating, and reaching agreement with the patient, possibly given instructions, and printed information about treatment. An alert in the final seconds of the task increases the probability of it being ignored

Objective measure of time of whole consultations

Impact on time: neither increase nor decrease

Henderson et al. 2013 [49, 50]

UK

To determine

uptake of online diagnostic CDS and impact on clinical decision-making

and patient management and to elicit users’ views of utility

Condition of focus: Generic

Setting: General Practice

Tool: online diagnostic CDS

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: GP

- Risk score: No

Mixed: focus group + survey

Whether and how well the system had been embedded in everyday practice, based on the evidence available from the focus groups and post-use survey

Low usage reported

There was conflict at the organisational level, as agreement to participate in the study had been primarily by practice managers, while CDS use was to be by clinicians. This was linked to the major issue of no time having been identified for clinicians to use the system during a consultation

Searches took 4 min within a 10 min consultation: ‘We have so many things thrown at us…the PCT telling us to do this and that you can get a little overwhelmed.’ (GP)

Perception and objective measure of time to use tool

Impact on time: Increase

Driving perception: workload already heavy

Heselmans et al. 2012 [51]

Belgium

To assess users’ perceptions towards the implemented EBMeDS, the investigation of user interactions with the system and possible relationships between perceptions and use

Condition of focus: Generic

Setting: Family Practice

Tool: CDS for a range of conditions

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: GP

- Risk score: No

Mixed: quantitative survey + qualitative interviews

Qualitative: factors that may account for acceptance and use of EBMeDS

Quantitative: computer-recorded user interactions with the system over evaluation period of 3 months to assess the actual use of the system

Although majority of FPs were positive about the system, the most important reasons to neglect reminders related to the number of reminders and lack of time to read them (44%). However, 35% reported they could perform their tasks faster using the system

Quantitative analysis of physicians’ log files:-

Study measured number of seconds for a reminder to be closed after appearing, but this is only referred to in the discussion:

- reminders open for less than 3 s were assumed to have been 'clicked away' (ie ignored)

- 49% of alerts were open for < 2 s and 32.5% open for < 3 s which suggests that sensitivity threshold may have been too low

Perception

Impact on time: Mixed views

Hirsch et al. 2012 [52]

Germany

To evaluate the uptake of an interactive, transactional, and evidence-based library of decision aids and its association to decision making in patients and physicians in the primary care context

Condition of focus: Range

Setting: Primary Care

Tool: CDS for a range of conditions, including CVD, AF, CHD, diabetes and depression

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: GP

- Risk score: No

Quantitative survey

Which module was used and how detailed the steps of the shared decision making process were discussed using a four point scale

Physicians were asked who made the decision at the end of the consultation, and for a subjective appraisal of consultation length (“unacceptably extended”, “acceptably extended”, “neither nor”, “shortened”)

Subjective appraisal of consultation length: in 8.9% of consultations physicians said that they were “unacceptably extended” by the CDS, 76.3% of consultations were “acceptably extended”, 14.2% “neither nor”, and 0.5% were “shortened”

Majority of physicians stated that the consultation length was either not extended or ‘acceptably’ extended

Log files analysis reported average consulting time was 8 min, so use of CDS was therefore not extending the usual 10 min appointment slot

Perception

Impact on time: Mixed views

Holt et al. 2018 [53]

UK

To identify the barriers

to automated stroke risk assessment linked

to invitations and screen reminders in primary care (AURAS-AF)

Condition of focus: Stroke prevention in Atrial Fibriliation

Setting: General Practice

Tool: stroke risk assessment

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: GP

- Risk score: Yes

Mixed: quantitative analysis of useage data + interviews

Quantitative: coded data indicating the responses to the screen prompts

Qualitative: Researcher-led issues around AURAS-AF, and allowed people to express their own experiences and priorities

Time available and the patient's own agenda dictated whether the alert was used to introduce the topic into the consultation. In some cases, GPs recognised that the timing was not right to initiate a discussion

GP estimated the alert added 5–10 min more on the consult ('so you leave it')

Perception

Impact on time: Increase

Driving perception: impact on conversation

Hoonakker et al. 2012 [54]

USA

To examine barriers, and possible improvements to a tool, HeartDecision (HD)

Condition of focus: Cardiovascular disease

Setting: Primary care

Tool: cardiac risk assessment

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: GP

- Risk score: Yes

Mixed: quantitative time study + survey + qualitative interviews + observations

A stop watch was used to measure the time the physicians spent on the different pages of the tool

Survey: additional information about the need for such tools, use of the tool, barriers against its use, facilitators, and possible improvements

The time study showed that on average, physicians spent 13 min using the tool, which is 'too long' for a regular patient visit, which lasts on an average 10 min

Objective measure of time to use tool

Impact on time: Increase

Kortteisto et al. 2012 [55]

Finland

To assess and describe in depth the specific reasons for HPs using or not using the eCDS in primary care

Condition of focus: Generic

Setting: Primary care clinic

Tool: CDS for a range of conditions

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: GP

- Risk score: No

Mixed: focus group + survey

Focus groups: general ideas about the eCDS, experiences of the use, practical problems, advantages /disadvantages for work, barriers to use and facilitators, and development issues

Survey: system’s capacity and quality, as well as its perceived usefulness and ease of use

Common barrier was busy practice in primary care

‘When I am busy, I don’t look for anything really.’

‘Nothing more than simply doing what I have to do.’

Within 'functionality', majority of clinicians reported it was 'rapid enough'

Within ‘usefulness’, drug alerts 'motivate' but 'take time' and 'requires more time for paperwork'

Perception

Impact on time: Mixed views

Krog et al. 2018 [56]

Denmark

To explore facilitators and barriers to using the eMDI in psychometric testing of patients with symptoms of depression in Danish general practice

Condition of focus: Depression

Setting: General Practice

Tool: CDS for diagnosis/monitoring of patients with depression

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: GP

- Risk score: Yes

Qualitative interviews

Determinants for using the eMDI in relation to the GPs’ capability, opportunity and motivation to change clinical behaviour

eMDI was a 'timesaver' compared to the paper version because of cutting out need for data entry or printing and scanning which frees up time for other tasks, e.g. more time for dialogue in the consultation (i.e. 'better' consultations through improved use of consultation time and prioritisation of GPs' time)

However, for some interviewees, time and efficiency aspects have worked as a barrier because of lack of time to change routines and experiences with the eMDI as being too time-consuming when filled in during the consultation

Perception

Impact on time: Mixed view

Lafata et al. 2016 [57]

USA

To evaluate the association of exam room use of EMRs, HRA tools, and self-generated written

patient reminder lists with patient–physician communication, recommended preventive health service delivery, and visit length

Condition of focus: Generic

Setting: Primary care

Tool: range of tools, including EMR tools, risk assessment tools and written patient lists

- Embedded/linked with EMR: Range

- Interruptive alert: Range

- User-driven: Range

- Risk score: n/a

Quantitative: observational

1. Visit length (face-to-face interaction time in minutes between patients and physicians);

2. Patient engagement communication behaviour;

3. Physician–patient-centred communication behaviour; and

4. Physician delivery of evidence-based preventive health services

On average, physicians spent almost 27 min with the patient (SD = 10 min)

Mean visit length was longer for patients who used a self-generated written reminder list compared to patients who did not use such a list (30.0 vs. 26.5 min). Visit length was also significantly longer when the EMR was accessed in the exam room compared to those visits in which the EMR was not accessed in the exam room (27.7 vs. 23.9 min)

Visits that included exam room–based use of the EMR lasted, on average, just over 3 min more than visits in which the EMR was not accessed in the exam room

The use of a HRA instrument was not associated with increased visit length, but was not associated with decreased length either

Objective measure of time of whole consultations

Impact on time: neither increase nor decrease

Litvin et al. 2012 [58]

USA

To describe use of the

CDS, as well as facilitators and barriers to its adoption, during the first year of the 15-month intervention

Condition of focus: Prescribing

Setting: Primary care practices

Tool: CDS for antibiotic prescribing for Acute Respiratory Infections

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: Physician

- Risk score: No

Mixed: quantitative analysis of EMR data + qualitative interviews and observations

Using EMR data, CDS use was calculated at the practice level as the number of encounters at which an ARI diagnosis (or multiple diagnoses) using the CDS was made divided by the number of all encounters at which an ARI diagnosis was made, regardless of CDS use

Qualitative data were recorded during practice site visits using a structured site visit field note

Group interviews with staff elicited facilitators and barriers of CDS adoption

Organisational factors:

- Barrier: 'use of CDS alters workflow'

- Facilitator: perception that CDS speeds up the visit and shortens documentation time. Others felt that the CDS did not affect the length of the visit. None reported that the CDS slowed the visit

Perception

Impact on time: Mixed view

Lugtenberg et al. 2015 [59]

Netherlands

To investigate the exposure to and experiences with the CDS quality improvement intervention, to gain insight into the factors contributing to the intervention’s impact

Condition of focus: Generic

Setting: General Practice

Tool: CDS for range of activities, including patient data registration, prescribing and management

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: GP

- Risk score: No

Mixed: quantitative analysis of usage data + survey + qualitative interviews

Quantitative:

- NHGDoc data to measure exposure to the intervention in both study groups

- Survey data on exposure to and experiences with the CDS intervention

Qualitative: range of barriers that

GPs and PNs perceive in using NHGDoc or similar CDS in practice

Survey:

- Limited time available during and after consultation (60% of GPs and 16% of PNs)

- Too much additional work required during and after consultation (60% of GPs, 27% of PNs)

Perception

Impact on time: Increase

Driving perception: Lack of time

Lugtenberg et al. 2015 [59,60,61]

Netherlands

To identify perceived barriers to using large-scale implemented

CDS, covering multiple disease areas in primary care

Condition of focus: Range

Setting: General Practice

Tool: CDS for range of conditions, including CVD, asthma/COPD, diabetes, thyroid disorders, viral hepatitis, AF, subfertility, gastro protection and chronic renal failure

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: GP

- Risk score: No

Qualitative focus groups

Value of CDS in a primary care setting, CDS in an ideal world, experiences with using CDS with the example of NHGDoc, perceived advantages and disadvantages, and barriers to using them in practice

The system’s responsiveness was a problem, with the loading of alerts taking too long

Many physicians mentioned that using CDS has a negative effect on patient communication during consultation and is considered a barrier to their use

Discrepancy between a patient’s reason for visiting and the alert content was a reason not to use it

Limited time during consultations made it difficult to use the CDS, as well as the additional work it requires

Perception

Impact on time: Increase

Driving perception: slow software, workload already heavy

Pannebakker et al. 2019 [62]

England

To understand GP and patient perspectives on the implementation and usefulness of the

eCDS

Condition of focus: Cancer

Setting: General Practice

Tool:

- Type: CDS for melanoma

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: GP

- Risk score: No

Qualitative interviews

GP and patient perspectives

Some reflected on how using CDS did not intrude in a consultation, and that it could help with saving time during or after a consultation

Perception

Impact on time: Decrease

Driving perception: efficiency, reduced time needed for data entry

Peiris et al. 2009 [63]

Australia

To develop a valid CDS tool that assists Australian GPs in global CVD risk management, and to preliminarily evaluate its acceptability to GPs as a point-of-care resource for both general and underserved populations

Condition of focus: Cardiovascular disease

Setting: General Practice

Tool: CDS for CVD risk management

- Embedded/linked with EMR: No

- Interruptive alert: Yes

- User-driven: GP

- Risk score: Yes

Mixed: quantitative survey + qualitative interviews

Survey: GP attitudes about the tool and management provided

Interviews: general attitudes about

the tool and its impact on the consultation; a review of specific tool outputs; recommendations for future tool development

Challenges:

- Time pressures introduced by incorporating CVD risk management into routine care

- Extra work seen in cases where the GP didn't expect CVD risk to be high, but these instances were few

- Future automation of the tool (e.g. pre-population with data) seen as important

Recommendations

- ‘Too wordy' to read whilst with patient. For a consultation, 'you've got 15 min at most'

Perception

Impact on time: Neither increase nor decrease

Driving perception: work was increased only where risk was unexpectedly high, but this was not often

Rieckert et al. 2018 [64]

Germany

To examine how GPs experienced the

PRIMA-eDS tool, how GPs adopted the recommendations provided by the CMR, and explore GPs’

ideas on future implementation

Condition of focus: Prescribing

Setting: General Practice

Tool: CDS to prevent inappropriate medication in older populations

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: GP

- Risk score: No

Qualitative interviews

1. Polypharmacy in everyday practice

2. Using the eCRF

3. General overview of the comprehensive medication review

4. Output of the CMR and how GPs responded to the recommendations

5. Implementation of the tool into daily practice routine

Entering patient data into the eCRF was time-consuming. After a period of familiarisation utilisation became easier and faster ‘For the first one I took 45 min I think and in the end it took me ten minutes’. (GP 14)

Retrieving additional information provided by the tool was perceived as being too time-consuming

Perception

Impact on time: Mixed views

Rickert et al. 2019 [65]

Germany

To examine how GPs experienced the

PRIMA-eDS tool, how GPs adopted the recommendations provided by the CMR, and explore GPs’

ideas on future implementation

Condition of focus: Prescribing

Setting: General Practice

Tool: CDS to prevent inappropriate medication in older populations

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: GP

- Risk score: No

Quantitative survey

Use of and attitudes toward the CMR, its recommendations, and future use

Prerequisites for the future use of the PRIMA-eDS tool:

Technical limitations were rated by 93% of GPs as important for future use of PRIMA-eDS, data security by 86%, and time requirement by 85%

DISCUSSION: Previous research has shown that physicians ignored alerts when this was not the reason for the patients’ visit, as often there was not enough time to deal with both

Perception

Impact on time: Unclear

Robertson et al. 2011 [66]

Australia

To determine GPs’ access to and use of electronic information sources and CDS for prescribing

Condition of focus: Prescribing

Setting: General Practice

Tool: CDS for prescribing

- Embedded/linked with EMR:

- Interruptive alert:

- User-driven: GP

- Risk score: No

Qualitative interviews

Electronic resources/CDS:

- advantages and disadvantages of electronic over paper-based resources,

- valued features of electronic decision support systems,

- features of alerts and reminders (content, presentation and perceived usefulness),

- support and training needs

GPs mentioned the pressures of a 10- to 15-min consultation, that their information needs were immediate at the point of care. GPs wanted relevant information presented concisely, easily searchable, integrated in the workflow and embedded in clinical software (the need to logon or go outside the main programme was seen as a burden and time waster)

Perception

Impact on time: Unclear

Sperl-Hillen et al. 2018 [67]

USA

To evaluate whether

the CDS intervention can improve 10-year CVD risk trajectory in patients in primary care setting

Condition of focus: Cardiovascular disease

Setting: Primary Care

Tool: assessment of CV risk

- Embedded/linked with EMR: Yes

- Interruptive alert:

- User-driven: GP

- Risk score: Yes

Quantitative: analysis of EMR + survey

Primary: CV risk values and clinical impact of the CDS system

Secondary: Pre- and post (18 m) survey of Primary Care physicians:

- Confidence and preparedness to address CV risk with patients

- Satisfaction and perceptions with the CDS

PCPs reported that the CDS helped them to initiate discussions about CV risk (94%), improved CV risk factor control (98%), saved time when talking about CV risk with patients (93%), enabled efficient elicitation of patient treatment preferences (90%), supported shared decision making (95%), and influenced treatment recommendations (89%)

Perception

Impact on time: Decrease

Driving perception: saved time in conversations with patients

Sperl-Hillen et al. 2019 [68, 69]

USA

To evaluate improvements to clinical outcomes, impact on clinic workflow, use of CDS and satisfaction among clinicians

Condition of focus: Chronic disease

Setting: Primary Care clinics

Tool: CDS for chronic disease management & preventive care

- Embedded/linked with EMR: Yes

- Interruptive alert:

- User-driven: GP

- Risk score:

Quantitative: analysis of EMR, CDS useage data, survey of clinicians

Clinical outcomes

Impact on clinic workflow

CDS use rates

Clinician satisfaction

93 percent reported it saved time when talking to patients about CV risk factor control

Perception

Impact on time: Decrease

Driving perception: saved time in conversations with patients

Sukums et al. 2015 [70, 71]

Sub-Saharan Africa

To describe health workers’ acceptance and use of the eCDS for maternal care in rural primary health care (PHC) facilities of Ghana and Tanzania and to identify factors affecting successful adoption of such a system

Condition of focus: Antenatal and intrapartum care

Setting: Primary Health Care clinics

Tool:

- Type: CDS for antenatal and intrapartum care

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: Clinician

- Risk score: No

Mixed: quantitative survey + interviews

Perceived challenges affecting the eCDS use through a mid-term- and post- survey at 10 months (midterm) and 18 months (final) after implementation

Interviews with the care providers were conducted to explore their views and experiences with the eCDS

Perceived increase in workload due to the eCDS use reported

About one third of providers indicated a lack of time to use the eCDS

Reasons given for these challenges: inadequate computer skills, inadequate staffing during busy periods

Perceived workload also increased due to simultaneous manual and electronic documentation, which some providers felt to disrupt their work

Perception

Impact on time: Increase

Driving perception: stand-alone data entry, workload already heavy

Trafton et al. 2010 [72, 73]

USA

To evaluate the usability of ATHENA-OT, and to identify key needs of clinicians for both integrating the CDSS into their workflow and for opioid prescribing in general

Condition of focus: Prescribing

Setting: Primary Care

Tool: CDS for use of opioid therapy for chronic, non-cancer pain

- Embedded/linked with EMR:

- Interruptive alert:

- User-driven: Clinician

- Risk score: No

Mixed: quantitative and qualitative observations, survey, interviews and usage data

Usability of ATHENA-OT

Key needs of clinicians

Qualitative: Many competing time constraints limit use of a CDS for OT. While the CDS streamlines and facilitates practices recommended in the CPG, they still require time to complete

Quantitative survey: ATHENA-OT system was rated lowest on expectations that it would save time in visits

Provider Shadowing: Clinic visits varied from 13 to 59 min and averaged 31 min. 10/35 visits involved the ATHENA-OT. In these 10 visits, the time ATHENA-OT was used ranged from 3 s to 10 min

Clinicians appeared to have reasonable time to use the system. This contradicts clinicians’ self-reported lack of time during visits, reflecting either non-representativeness of the visits observed, or exaggeration of time constraints by clinicians

Perception and objective measure of time showed conflict

Impact on time: mixed views

Trinkley et al. 2019 [74]

Canada

To describe current clinician perceptions

regarding beneficial features of CDS for chronic medications in primary care

Condition of focus: Prescribing

Setting: Primary Care

Tool: CDS for prescribing chronic medications

- Embedded/linked with EMR:

- Interruptive alert:

- User-driven: Clinician

- Risk score: No

Qualitative focus groups

Beneficial CDS features for chronic medication management in primary care

Participants' ideal CDS for chronic medications

Potential unintended consequences of the CDS

Main beneficial features of alerts:

(1) non-interruptive alerts; (2) clinically relevant and customisable support; (3) summarisation of pertinent clinical information and (4) improving workflow

Alerts were “one more thing to get through” and a barrier to completing tasks. Clinicians reported ‘alert fatigue’, with an overwhelming number of alerts for ‘every patient’

While not universally endorsed, some indicated they liked one alert for lung cancer screening and found it helpful, because it interrupted workflow at the right time

No consensus regarding best timing of an interruptive alert. Roughly equal numbers preferred the to alert at: (1) opening of an encounter; (2) ordering or reviewing a medications; (3) entering a diagnosis or (4) at the end of the encounter

Perception

Impact on time: Unclear

Voruganti et al. 2015 [75]

Canada

To investigate current practices for assessing risk, awareness and use of risk assessment tools in primary care, and to assess PCPs’ perspectives regarding the usefulness, usability and feasibility of implementing computer-based health risk assessment tools into routine clinical practice

Condition of focus: Chronic disease

Setting: Primary Care

Tool: risk assessment for chronic diseases

- Embedded/linked with EMR:

- Interruptive alert:

- User-driven: Clinician

- Risk score:

Qualitative focus groups

PCPs' awareness of risk assessment tools, and views on their usefulness, usability and feasibility of routinely using them in clinical practice

Perceived benefits and shortcomings of tools:

- beneficial for initiating discussion, engaging patients in risk discussions, and guiding decision-making by physicians and patients

- concern about impact on workflow (“it might bring up a lot more other issues that they [patients] weren’t originally aware of and the discussion might actually… be less directed”)

- some felt differently, that “it usually stops a lot of the meandering dialogue that you’d otherwise engage in”

Expectations of an ideal risk assessment tool:

- number of steps to complete a risk assessment should be minimised to a few clicks

Perception

Impact on time: Mixed view

Walker et al. 2017 [76, 77]

Australia

To examine useability and acceptability of a prototype tool ‘CRISP’ (Colorectal cancer

RISk Prediction tool), identify barriers and enablers to implementing CRISP in Australian general practice, and optimize the design of CRISP prior to an RCT

Condition of focus: Cancer

Setting: General Practice

Tool: risk assessment for colorectal cancer

- Embedded/linked with EMR:

- Interruptive alert:

- User-driven: Clinician

- Risk score:

Qualitative: simulated consultations + interviews

Acceptability, usability and implementation strategies were explored at an individual level (GP, PN and PM) and organizational level (the practice) using the four domains of NPT:

- Coherence

- Cognitive participation

- Collective action

- Reflexive monitoring

Collective action

- GPs, PNs and PMs all agreed that lack of GP consultation time would limit the use of CRISP by GPs

- Consensus that nurses have the capacity, time and

expertise to complete the risk assessment as part of routine preventive health consultations

- Opinions about who would take responsibility for the final decision about screening advice was split between GPs and PNs; many GPs feared missing a diagnosis

Perception

Impact on time: Increase

Driving perception: lack of time

Zazove et al. 2017 [78]

USA

To develop a model electronic alert that integrates into system 1 thinking (thinking that is fast and intuitive, often occurring without much

conscious thought), which family medicine clinicians would use to improve identification of individuals at risk for HL

Condition of focus: Hearing loss

Setting: Family Medicine clinic

Tool: risk assessment for hearing loss

- Embedded/linked with EMR:

- Interruptive alert:

- User-driven: Clinician

- Risk score:

Mixed: cognitive task analysis interviews

How often various issues were identified, the root causes of use and non-use of the electronic alert,

sample quotes highlighting major issues, and any potential solutions mentioned

Time pressure with electronic prompts:

- Clinicians felt visits were already overloaded, limiting their ability to handle additional alerts. Addressing all recommendations for complex patients requires more than the typical 15-min office visit

- Alerts intrude on the doctor-patient relationship, since they rarely address the primary reason for the visit, and the added workload contributes to clinician stress due to falling further behind in the schedule

Hearing loss is not easily addressable:

- the “time pressure” was due to clinicians being uncomfortable and having to take time to think about how to address HL (ie, being forced into slow and effortful system 2 thinking), which they did not have to do with other conditions

Perception

Impact on time: Increase

Driving perception: workload already heavy

Murdoch et al. 2015 [79, 80]

UK

To use conversation analysis to assess the interactional workability of using CDS for telephone triage

Condition of focus: Same-day appointment requests (range of conditions)

Setting: General Practice

Tool: CDS to guide nurse-led telephone triage

- Embedded/linked with EMR: Yes

- Interruptive alert: No, guides triage call

- User-driven: Nurse

- Risk score: No

Qualitative: conversation analysis

1. Structuring of patient's problem

2. making sense of/managing pt's symptoms in the CDS

3. where pts' experience misaligned with CDS requirements

4. nurse accountability within CDS

5.Consequences of not using CDS on Qs and answers

Use of CDS impacted call 'trajectory' and caused disruptions 'interactional workability' of using the CDS for telephone triage

Eg. Operational problems such as mistyping a symptom or condition led to a 'prolonged pause' while nurse attempted to correct/search around for another term and explain the delay to the patient

Objective measure of time of whole consultations but timings data not reported

Impact on time: unclear

Jetelina et al. 2018 [81]

USA

Proof of concept study:

before and after implementation of e-tool

Condition of focus: Behavioural Health

Setting: Primary care clinics

Tool: suite of e-tools for Behavioural Health Clinicians

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: Clinician

- Risk score: No

Mixed: quantitative surveys + qualitative interviews and observations

Clinical outcomes and patient experience

Acceptability of the e-tools

Factors influencing implementation

Acceptability:

- Tool was acceptable and easy to use

- Tool added 1 to 2 min to the initial visit but time during follow-up visits by automatically populating the history of the presenting illness and patient instructions at subsequent visits

Perception

Impact on time: Decrease

Driving perception: efficiency, reduced time needed for data entry

McGinn et al. 2013 [82]

USA

To examine the effect of the tools on diagnostic and treatment patterns and to assess adoption of the tool for each condition

Condition of focus: Upper Respiratory Tract Infections

Setting: Primary care clinics

Tool: CDS with clinical prediction rules for 2 URTIs

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: Yes

Quantitative: analysis of EMR and usage data

Usage data: number of visits involving:

- tool being opened once triggered

- calculator being completed

- viewing of recommendations and

- following of recommendations

Time not measured or commented on

Regarding diagnostic/treatment/management patterns, no significant differences between arms in proportions of visits resulting in patient returning to ED/Outpatient clinic for follow-up

High adoption rates reported

Objective workload measure of follow-up visits

Impact on workload: neither increase nor decrease

Litvin et al. 2016 [83]

USA

To assess impact on CKD clinical quality measures and facilitators/barriers to use of tools

Condition of focus: Chronic Kidney Disease

Setting: Primary care clinics

Tools: CDS tools for CKD, including risk assessment

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: Yes

Mixed: quantitative analysis of EMR data + qualitative observations and interviews

Quantitative: CKD clinical quality measures at baseline & 2 years

Qualitative: Barriers/facilitators to using tools

Barriers included mention by some staff that CDS tools required 'extra clicks' and additional steps outside of existing workflow

Perception

Impact on time: Increase

Driving perception: workflow disruption

Linder et al. 2009 [84]

USA

To assess effect of CDS on antibiotic prescribing rates for ARI visits

Condition of focus: Acute Respiratory Infections

Setting: Primary care clinics

Tool: CDS for ARIs to help reduce inappropriate prescribing

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: Yes

Quantitative: analysis of EMR data

Primary: Rate of antibiotic prescribing for ARI visits

Secondary: 30-day re-visit rates attributable to ARIs

Recorded duration of Smart Form use (assume mean) 8.1 m, sd 5.8 m. However, whole visit length not captured/reported and not compared with Usual Care

Re-visit rate attributable to ARIs 8% in intervention and 9% in control but not remarked upon in Discussion or quantified as significant or not significant

Remarked in discussion that to be effective, CDS must fit as seamlessly as possible into existing workflow and allow clinicians to manage unanticipated interruptions

Objective measure of time to use tool and revisit rates

Impact on time: Unclear

Revisit rates not remarked upon

Ranta 2013 [85]

New Zealand

To assess feasibility of introducing risk tool to help timely management of TIAs

Condition of focus: TIA & Stroke

Setting: General Practice

Tool: CDS for TIA & Stroke risk

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: GP

- Risk score: Yes

Quantitative: analysis of usage data + survey

Usage of the tool and advice rendered/actions taken by GPs

Post-pilot satisfaction of GP users

GP survey interviews reported 'no major concerns' regarding the time required to enter data (Methods report this to be 3-5 min per TIA patient)

Time not formally measured and no indication given of whether time is added to the consultation (perhaps 'acceptably')

Perception

Impact on time: Unclear

Price et al. 2017 [86, 87]

Canada

To examine how 40 STOPP rules could be implemented as alerts into practice and the impact on prescribing

Condition of focus: Prescribing

Setting: Family Practices

Tool: Screening tool of older people's prescriptions (STOPP)

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Physicians

- Risk score: No

RCT with mixed methods: quantitative analysis of EMR data + interviews

Quantitative: change in rate of potentially inappropriate prescriptions (PIPs) between arms

Qualitative: views on barriers and facilitators of implementation

Qualitative interviews

- 'workflow' cited as a barrier to implementation, along with 'location' of alert on-screen

- Workflow not expressed in terms of time (increase or decrease) or sequence of activity and not quantified or measured as time

Perception

Impact on time: Unclear

Wan et al. 2010 [88]

Australia

To explore GPs and patients' views of implementing CVAR assessment, including issues regarding identifying patients at risk and the timing and context for assessment

Condition of focus: Cardiovascular disease

Setting: General Practice

Tool: Range of electronic and paper-based tools for cardiovascular absolute risk assessment

- Embedded/linked with EMR: Unclear

- Interruptive alert: Unclear

- User-driven: Unclear

- Risk score: Yes

Qualitative interviews

Views of barriers and facilitators of implementing CVAR assessment

No specific e-tool examined and time not mentioned, but a general comment in Discussion that GP workload pressure is an important barrier to increasing preventive activity in general

GP workload pressure

Impact on time/workload: no conclusion

Hor et al. 2010 [89]

Ireland

To assess prevalence and use of EMR and any form of CDS for prescribing and to explore perceived benefits of future introduction of CDS-eP, barriers to implementation and presumptive responses to prescribing alerts

Condition of focus: Prescribing

Setting: General Practice

Tool: Hypothetical CDS for e-prescribing

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Unclear

- Risk score: No

Quantitative: survey + free text

Prevalence and use of EMR and any form of CDS for prescribing

GPs' perceived benefits of future introduction of CDS-eP, barriers to implementation and presumptive responses to prescribing alerts

Time not measured but mentioned in GPs' general comments: hypersensitive interruptive alerts whilst prescribing and causing a delay to prescribing by e.g. 20 s would be frustrating

Perception

Impact on time: Increase

Driving perception: workload already heavy

Troeung et al. 2016 [90]

Australia

To develop and evaluate performance of the e-screening tool against practice EMR data

Condition of focus: Familial hypercholesterolaemia

Setting: General Practice

Tool: screening tool to identify patients with familial hypercholesterolaemia

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: GP

- Risk score: Yes

Quantitative: analysis of EMR and tool data

Performance of the e-screening tool

Time reported (10 min) to run the e-screening search, not consultation length

Objective measure of time to use tool

Impact on time: Unclear

Jimbo et al. 2013 [91]

USA

To identify PCPs' perceived barriers and facilitators to implementation

Condition of focus: Cancer

Setting: General Practice

Tool: CDS for patients regarding their colorectal cancer screening preferences, linked to computerised reminder alerts for clinicians

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Patient

- Risk score: No

Qualitative focus groups

Barriers and facilitators to implementation

Clinicians (majority) identified principal barriers to patients' access to colorectal cancer screening and patients' concerns regarding costs, but also time constraints during visits to discuss the screening options (e.g. could mean a 5–10 min conversation)—the web-based tool completed by patients prior to their visit could potentially save time at the visit

Some concerns over how clinician reminder alerts would fit into the usual visit workflow, but not expanded upon

Perception

Impact on time: mixed view

Akanuwe et al. 2020 [92]

UK

To explore the views of service users and primary care practitioners on how best to communicate cancer risk information when using QCancer, a cancer risk assessment tool, with symptomatic individuals in primary care consultations to enable them be involved in decisions on referral and cancer investigations

Condition of focus: Cancer

Setting: General Practice

Tool: Qcancer risk assessment tool

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: GP

- Risk score: Yes

Qualitative interviews and focus groups

Personalising risk information

Informing and involving patients

Being open and honest

Providing time for listening,

explaining and reassuring in the context of a professional approach

‘Talking about risk is quite difficult’

- GP may be reluctant to inform the patient about cancer risk when they themselves were uncertain about the risk calculated or how to communicate this

Patients:

- GPs should take time to talk to patients to gain their confidence and show they care: 'You wouldn't want to feel that you've been rushed’

- ‘GPs would need more time to use the tools in consultations'

GPs: GPs expressed the need to provide more time to provide explanations to patients

Perception

Impact on time: Increase

Driving perception: time needed to use the tools, convey information and show caring

Bangash et al. 2020 [93]

USA

To develop a CDS tool for Familial Hypercholesterolemia based on physician feedback from qualitative interviews, usability testing and an implementation survey

Condition of focus: Familial Hypercholesterolemia

Setting: Primary Care

Tool: CDS for FH

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: GP

- Risk score: Yes

Mixed: Qualitative interviews, usability testing + survey

 

The most common barrier is the increasing cognitive burden on providers due to EMR complexity and limited time during clinical encounters

Most physicians are receptive towards CDS. The only survey item where the majority of the physicians gave either a neutral response or disagreed was regarding the CDS tool ‘not’ increasing time spent with a patient

This response reiterated the need for CDS to be designed to increase e ciency and not add to provider burden

Perception

Impact on time: Increase

Driving perception: workflow disruption, limited time during consultations

Bradley et al. 2021 [94]

UK

To synthesise qualitative data of GPs’ attitudes to and experience with a range of CDs to gain better understanding of the factors shaping their implementation and use

Condition of focus: Cancer

Setting: Primary Care

Tool: Range of CDS tools for cancer

- Embedded/linked with EMR: Range

- Interruptive alert: Range

- User-driven: Range

- Risk score: Yes

Systematic review—qualitative synthesis

Impact of CDS on role of GP

- communicating risk

- collaboration with secondary care/guidelines

- nature of training provided

Elements determining GPs' use

- clinical acumen v protocol

- medicolegal issues

Impact on GPs work

- increasing awareness of cancer

- prompt fatigue

- impact of IT integration (time)

- time as a resource

GPs' reflections

- unintended consequences

- investigation and referral patterns

- 'think cancer'

Prompt fatigue

- Prompt fatigue was mentioned by several studies. The interruptions impacted on the flow of the consultation

The prompts were regarded, in some studies, as making work more difficult; another commented on the usefulness of prompts for future consultations

Impact of IT integration

- ‘It was not easy accessing the tools during patient

consultation’

Time as a resource

- Recognition of the benefits of using a CDS was essential to justify the additional time required for its use. This impacts on consultation, time required to train users and the additional effort to continue using the CCDT. Time is at a premium in general practice in the UK: the pressures of the 10 min appointment, to keep up to date and to attend training

Perception

Impact on time: Mixed views

Driving perception: time consuming to complete, limited time during consultations

Breitbart et al. 2020 [95]

Germany

To assess how CDS vs standard consultations affect patient satisfaction, diagnostic accuracy and length of consultations

Condition of focus: Skin conditions

Setting: General Practice

Tool: Visual CDS for dermatology consultations

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: GP

- Risk score: No

Randomised feasibility study

Patient experience and satisfaction

Diagnostic accuracy

Consultation length

The median duration of the consultations using the CDS was 10 min, similar to that in the standard arm

In the CDSS arm, overall patient satisfaction correlated negatively with increased duration of consultation (P = 0.02)

Across both arms younger patients (20-40y) were more bothered about consultation length relative to the older patients

Overall, the CDSS increased aspects of patient satisfaction, improved diagnostic accuracy without influencing the duration of the consultation

Objective measure of time of whole consultations

Impact on time: neither increase nor decrease

Byrne et al. 2015 [96]

Ireland

To benchmark the awareness and use of Risk Assessment tools and CVD prevention guidelines along with barriers to their use among a sample of Irish GPs

Condition of focus: CVD

Setting [16, 97]: General Practice

Tool: CVD risk assessment tools

- Embedded/linked with EMR:

- Interruptive alert:

- User-driven: GP

- Risk score:

Cross-sectional survey of GPs

Demography

Risk assessment

CVD guideline use

Perception of barriers to use of Risk Assessment tools and CVD guidelines

Main three barriers to use of Risk Assessment tools:

1) patients focused on a single risk factor and not global picture (32.9%)

2) time constraints (30.6%)

3) not being used to using a risk calculator (18.4%)

Barriers to implementation of CVD prevention guidelines:

- lack of remuneration (40.8%)

- too many CVD guidelines (38.9%)

- time constraints (35.7%)

Perception

Impact on time: Increase

Driving perception: limited time during consultations

Caturegli et al. 2020 [98]

South Africa

To pilot a prescribing tool

Condition of focus: Tuberculosis

Setting: Primary Care clinics

Tool: prescribing tool for TB preventive therapy

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: Clinician

- Risk score: No

Mixed methods

Prescribing rates

Perceived barriers to prescribing

Workload

Stock-outs

Prescription guidelines

Intervention impact

Cognitive load

Documentation

Workload

- Reduces the writing one has to do

Documentation

- According to five of eight providers, time spent documenting medications and contraindications was reduced with the tool

Perception

Impact on time: Decrease

Driving perception: reduced time spent documenting medications and reduced cognitive load

Chadwick et al. 2017 [99]

UK

To evaluate feasibility and acceptability of a prototype application of a risk stratification algorithm incorporated into a CPOE and triggering a prompt to offer an HIV test when the healthcare worker is ordering other tests

Condition of focus: HIV

Setting: Hospitals and general practices

Tool: HIV testing prompt within a Computerised Physician Order Entry system

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: No

Qualitative: Interviews and focus groups

Frequency and appropriateness of the prompt

The prompt in the context of the consultation

Reactions of patients to the prompt

Impact of the prompt on HIV testing

Frequency and appropriateness of the prompt

- Little evidence of “prompt fatigue”. This particular prompt, compared with other prompts, was considered simple to understand and easy to manage

The prompt in the context of the consultation

- Most discussed blood tests and submitted an order with the patient present. Some GPs ordered the test after the patient had left and were faced with the dilemma of whether to bring the patient back to discuss HIV testing

- Many hospital-based and general practice HCWs felt the prompt was too late in the ordering process and disrupts the consultation, potentially opening up a new topic, causing irritation

Perception

Impact on time: Mixed views

Driving perception:

Either:

- no mention of time

- prompt causes test to be ordered after consultation

- disruptive if prompt comes too late in the ordering process

- potentially opens up a new topic right at the end of the consultation

Chadwick et al. 2021 [100, 101]

UK

To evaluate a prototype application designed to prompt in real-time, BBV testing in previously untested higher risk individuals attending primary care

Condition of focus: Blood-borne viruses

Setting: General practice

Tool: CDS to identify patients at risk of blood-borne viruses

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: Yes

Prospective cohort study

Number of 'hard prompts' and clinicians' responses

BBV tests ordered

Survey of GPs

Clinicians’ perceptions of the prompt system were positive with average additional time required for BBV test discussion in consultations estimated at 2 min

Nineteen percent of clinicians reported having to make an additional appointment after a BBV test prompt because of insufficient time during a consultation and 15% had to make an additional appointment to discuss test results

Free-text answers stressed the lack of time available

Median additional consultation time varied from 0.25 min when the clinician ignored the prompt to 2 min when the prompt was accepted or declined

Perception

Impact on time: Increase

Driving perception: limited time during consultations

Chima et al. 2019 [102]

UK

To summarise existing evidence on the effects

of eCDSTs on decision making for cancer

diagnosis in primary care, and determine

factors that influence their successful implementation

Condition of focus: Cancer

Setting: General practice

Tool: Range of CDS tools to support cancer diagnosis

- Embedded/linked with EMR: Range

- Interruptive alert: Range

- User-driven: Range

- Risk score: Range

Systematic review

Appropriateness of care (n = 5);

Diagnostic accuracy (n = 1);

Time to diagnosis (n = 1);

Cost-effectiveness (n = 1);

Process measures (n = 1); and

Qualitative (n = 4)

Introducing the tool disrupted the consultation, with GPs reporting feeling a loss of control

Additional tasks and time pressures impacted clinical flow

For eCDSTs designed for use during consultation, there were challenges due to disruption of the usual workflow and the generation of additional tasks in an already-busy appointment

Perception

Impact on time: Increase

Driving perception: limited time during consultations, disruption, loss of control, additional tasks and time pressures, impact on clinical flow

Dobler et al. 2019 [103]

USA

To determine clinician outcomes in RCTs of encounter decision aids for Shared Decision Making

Condition of focus: Range

Setting: General practice

Tool: Range of CDS tools to support shared decision making of screening/treatment options in consultations

- Embedded/linked with EMR: Range

- Interruptive alert: Range

- User-driven: Range

- Risk score: Range

Systematic review

Clinician satisfaction

- clinical encounter

- decision-making process

- the decision aid

- the decision made

Efficiency

- consultation length

Personal and professional well-being

- mood and burnout

- satisfaction with the practice of clinical care

Clinician satisfaction

- Communication was enhanced by providing visual representations of choices, reduced clinicians’ burden to produce accurate representations, giving clinicians more time to engage in meaningful discussions with patients

- Clinicians' concerns included that decision aids would add time to their clinics if they were not simple

Efficiency

- One study showed that 77% of clinicians in the decision aid group thought the decision aid was not disruptive and even potentially beneficial, 15% found it neither disruptive nor beneficial and 8% found it potentially disruptive

- 9/13 studies measuring consultation length found no significant difference in time between intervention and control groups. Three studies reported a longer and one study a shorter consultation time in the decision aid group

- One study evaluating why some of the clinicians in the intervention group did not use the decision aid in consultations, showed that clinicians’ perception that they do not have enough time was the main reason for not using it. Length of consultation was not measured, so it is unclear if using the decision aid did prolong the consultation time

Objective measure of time of whole consultations

Impact on time: neither increase nor decrease

Driving perception: limited time during consultations, perception that it will add time

Fiks et al. 2015 [104]

USA

To characterize patterns of adoption of the CDS system, assess the impact of performance feedback on CDS adoption by primary care clinicians, and measure the impact of CDS use on guideline adherence

Condition of focus: Otitis Media in children

Setting: Primary care

Tool: CDS for Otitis Media

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: No

 

Adoption of CDS

Impact of feedback on adoption

- use of documentation or order entry panels

Adherence to guidelines

Visit-level covariates:

- visit type

- type of OM

Clinicians concerned regarding the number of “clicks” needed to use the system, which was perceived as inefficient

Clinician enthusiasm for the tool was decreased because of the change in workflow that was required, especially for visits with multiple problems

Clinicians ignored the tool at 80 percent of eligible visits. Two percent of clinicians never used the CDS, and 11 percent used the tool during a trial period but not again

Perception

Impact on time: Increase

Driving perception: inefficient to use and causes changes in workflow

Ford et al. 2021 [105]

UK

To support and optimise the design of future CDSs by identifying factors that influence how or why GPs use these tools, looking specifically into aspects of CDSs they find useful and problematic, both individually and in

the wider context of their practice

Condition of focus: Dementia

Setting: General Practice

Tool: Hypothetical CDS for dementia risk prediction

- Embedded/linked with EMR: Range

- Interruptive alert: Range

- User-driven: Range

- Risk score: Range

Qualitative interviews

Trust in individual CDS

Usability of CDS in consultation context

Usability of CDS in broader practice context

Intrusiveness

Perceived as unhelpful where CDS raised an issue which the GP felt to be unimportant within that particular consultation; where the alert does not relate to a topic of importance for either GP or patient, it may be perceived as undermining of the GP’s professional expertise

- Self-population of CDS fields using previously-

recorded data (e.g. in QRISK) was viewed as a benefit which reduced intrusiveness and time pressures

Alert fatigue

- Negative impact on patient-doctor rapport: “It really is like an interruption”, “no GP wants somebody to just burst in with the door opening or the phone ringing. In the same vein no GP really wants a big thing to just pop up on the screen that they didn’t call up.”

- proliferation of alerts led to participants becoming desensitised to alerts, which could cause GPs to miss important safety alerts

Perception

Impact on time: No conclusion

Driving perception: limited time in consultations, workload already heavy

Henshall et al. 2017 [106]

UK

To explore the views

of clinicians, patients and carers.on feasibility and acceptability

Condition of focus: Psychiatric disorders (schizophrenia)

Setting: General Practice

Tool: Cloud-based CDS algorithm providing information on interventions

- Embedded/linked with EMR: Unclear

- Interruptive alert: Range

- User-driven: Clinician

- Risk score: No

Qualitative focus groups

Applications in clinical practice

Communication

Conflicting priorities

Record keeping and data management

Applications in clinical practice

- the tool did not reflect the complex clinical assessment process, being unable to capture detailed information about patient characteristics, time pressures, anxiety, influence of carers, clinician experience and organisational factors

- “When we see someone… it changes the conversation…Depending on how much time you have”

Communication

- some clinicians and patients/carers highlighted that receiving too much information might cause unnecessary worry and result in clinicians spending considerable time reassuring patients

- risk of entering into a ‘minefield of discussion’

Perception

Impact on time: Mixed views

Driving perception: limited time in consultations, discussion will add time

Holmstrom et al. 2019 [107]

Sweden

To describe factors affecting the use of a decision support tool and experiences among Telephone Nurses in Swedish primary health care

Condition of focus: Telephone nursing (range of conditions)

Setting: Primary Care

Tool: CDS providing guidelines/information and documentation in patient records

- Embedded/linked with EMR: Yes

- Interruptive alert: No, guides telephone call

- User-driven: Nurse

- Risk score: No

Qualitative: observations and interviews

Factors that decrease or cause deviation from CDSS

Positive factors

CDS complicates work

Long working experience, time pressure, lack of training, and non-native callers decreased CDS use

Because of time constraints, the TN sometimes chose to rely on their own professional knowledge instead of the CDS

Perception

Impact on time: Increase

Driving perception: limited time in consultations, reading text in the tool takes time

Kostopoulou et al. 2017 [108, 109]

UK

To measure the prototype’s effectiveness, usability, and potential impact on the consultation and patient satisfaction

Condition of focus: Generic

Setting: General Practice

Tool: CDS for diagnostic support for a range of conditions

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: No

Simulated patient study

Vision IT system recorded length of time patient record was open

GP and patient survey(s), including length of consultation

Mean length of baseline consultation = 13.73 min (2.96 SD)

Mean length of CDS consultation = 14.42 (5.28 SD)

Neither the number of investigations nor the length of consultation differed significantly between the baseline and CDS sessions

Patient satisfaction re consultation length similar at baseline and CDS consultations

Objective measure of time of whole consultations

Impact on time: neither increase nor decrease

Laka et al. 2021 [110]

Australia

To identify the different individual, organisational and system level factors

that influence the adoption and use of CDS

Condition of focus: Antibiotic management

Setting: Hospital and general practices

Tool: Range of CDS for antibiotic management

- Embedded/linked with EMR: Range

- Interruptive alert: Range

- User-driven: Range

- Risk score: Range

Quantitative survey

Survey

- Perceived benefit

- Perceived barriers

- Perceived facilitators

Free-text comments

- Lack of flexibility

- Information overload

- Information accuracy

Perceived barriers

- Clinicians in primary care more likely than those in hospital to believe that factors such as time limitation restrict the use of CDS

Information overload:

- Time and workload pressures make it difficult for clinicians to distinguish important information from irrelevant data

Perception

Impact on time: Increase

Driving perception: limited time in consultations

Lemke et al. 2020 [111, 112]

USA

To assess PCPs’ views of the tool and genomics-based CDS in clinical practice

Condition of focus: Geonomics (family health history screening)

Setting: Primary Care

Tool: Geonomics-based CDS to identify patients at risk

- Embedded/linked with EMR: Yes

- Interruptive alert: No

- User-driven: Patient completes tools, which alerts clinician based on answers

- Risk score: No

Qualitative interviews

Benefits to clinical care

Challenges in practice

CDS issues

Physician-recommended solutions

Time:

- Adding another topic to the patient’s annual visit, such as the alert recommendations, was difficult because of time constraints due to discussing other recommended screens and agenda items. Discussing the family history tool findings sometimes created difficulties in time management. “Because [physicians are] rushed and overburdened, if they know it’s going to take a lot of time, they’re going to ignore it.”

Workflow: Many clinicians reported having tight schedules and felt that adding another component to the visit, would tax existing processes

Perception

Impact on time: Increase

Driving perception: limited time in consultations, adds burden

Li et al. 2012 [113]

USA

To assess how providers interact with the

CDS while interviewing a simulated patient and to identify barriers to use prior to the implementation of a randomized controlled trial

Condition of focus: Upper Respiratory Tract Infections

Setting: Primary Care

Tool: CDS providing clinical prediction rules for Strep or Pneumonia

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: Yes

Usability testing and simulated patient study

Usability issues:

- Usability

- Navigation

- Content

- Workflow

Overall perception of the CDS had a positive-to-negative commentary ratio of 0.86 favouring the negative; the categories of ‘Navigation’ ‘Workflow’ were associated with the largest volume of negative comments

Average encounter duration: 2.03 min (5.11–18.35 min)

In 71% of cases (n = 17) the CDS was triggered after an average of 51% of the visit had elapsed. Clinicians spent on average 12.2% of encounter time using the CDS

Timing of trigger-

(1) Visits where CDS accessed at the beginning of the visit lasted on average 13:26 min

(2) Visits where CDS accessed at the end of the visit lasted on average 5:09 min

Objective measure of time of whole consultations

Impact on time: no conclusion as no comparison with control

Lo et al. 2018 [114]

Australia

To assess the usability and acceptability of the iPrevent prototype

Condition of focus: Cancer

Setting: Primary Care

Tool: Breast cancer risk assessment, providing tailored risk management information

- Embedded/linked with EMR: Yes

- Interruptive alert: No, guides visit

- User-driven: Clinician

- Risk score: Yes

Quantitative usability testing

Piloting using both simulated and real patients

Usability

Acceptability

Risk perception

Knowledge

Time spent completing tool

Consultation time

The median time taken for clinician consultations in which iPrevent data were discussed was 20 (range 5–45) minutes

Majority of clinicians felt the length of the tool was 'too long'

Perception and objective measure of time

Impact on time: mixed picture

Driving perception: length of time to complete tool too long

Margham et al. 2018 [115]

UK

To evaluate the impact of the electronic trigger tool, including acceptability to clinicians, ease of use, and rates of finding patient safety events

Condition of focus: Range

Setting: Primary Care

Tool: Trigger tools to identify patients at risk of safety-related incidents, including diagnostics, medication and communication, across a range of conditions

- Embedded/linked with EMR: Yes

- Interruptive alert: No, audit tool

- User-driven: Clinician

- Risk score: Yes

Mixed methods

Quantitative

- numbers of patients identified and reviewed

- rate of identification of patient safety events

Qualitative

- barriers and benefits to implementation,

- ease of use

- value of the trigger tool in the context of a busy GP surgery

GPs all expressed concern that the tool might identify too many patients at risk of harm, place further demands on GP time, and require additional resources to manage properly

- ‘Heart said “good idea”. Head said “hope it doesn’t significantly increase my workload”!’

Perception

Impact on time: Increase

Driving perception: limited time in consultations, workload already heavy

North et al. 2016 [116]

USA

To examine clinician time involved in risk calculation and decision making. This was done in a setting to estimate the minimum time it might take a provider at the point of care

Condition of focus: Cardiovascular disease, Atrial Fibrilation, Diabetes and Heart Failure

Setting: Primary Care

Tool: CVD risk assessment (within Ask Mayo Expert)

- Embedded/linked with EMR: Yes

- Interruptive alert: Unclear

- User-driven: Clinician

- Risk score: Yes

Case scenarios

Morae® Recorder software used to collect timing and usage

Risk calculation time

Combined risk calculation and clinical decision making time

AF CHADSVASC risk calculation 36 s (9 s)

AF total management time 85 s (18 s)

Lipids AHA-ASCVD risk calculation 45 s (12 s)

Lipids total management time 110 s (32 s)

HF SHFM risk calculation 171 s (42 s)

HF total management time 347 s (89 s)

Objective measure of time to use tool

Impact on time: authors concluded that time spent on risk calculation can be reduced by using automated algorithms

Olakotan et al. 2021 [117]

Malaysia

To identify factors affecting the appropriateness of CDSS alerts in supporting clinical workflow based on the proposed evaluation measures for CDSS alert

Condition of focus: Range

Setting: Primary Care

Tool: Range of CDS tools generating alerts to support clinical workflow

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: No

Systematic review

Technology factors

Human factors

Organisational factors

Process factors

Technology: 5 studies reported that alert overload increases the mental workload of clinicians

Human

- 11 studies showed that EMR-embedded asynchronous alerts increase clinicians’ workload

- Providing clinicians with protected time to respond to alerts reduces alert-related workload and improves patient safety

- Other instances of workload involve clinicians documenting clinical data into EMR before an alert can be triggered and selecting reasons for bypassing alerts

Perception and objective measure of workload

Impact on workload: Increase

Driving perception: alert overload increases mental workload, physical and cognitive weariness, no time to respond to alerts, time needed for documenting clinical data and selecting reasons for bypassing alerts

Porat et al. 2017 [108, 109]

UK

To identify facilitators and barriers to future DSS adoption

Condition of focus: Range

Setting: General Practice

Tool: CDS tools to support diagnosis

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: No

Mixed:

Qualitative interviews with GPs + quantitative survey of patients

Perception of GPs

Satisfaction of patients

Impact on consultation style and GP-pt interaction:

- ‘You need to get used to it…I do my consultations in a different way, but it works quite quick’

- Eight GPs (23%) were concerned that typing during the consultation would interfere with doctor-patient communication: “I normally chat and look at the patients, it throws my normal thing.” “I usually don’t code during the consultation, less contact with patient, my style is to listen for a long time.”

Time concerns

- Thirteen GPs (38%) felt consultation took longer with the tool than without. Without the tool, using only the EMR, GPs wrote mainly free text, which they perceived to be faster: “It will be hard to use it in a 10-min. consultation.”

- Average consultation time did not significantly differ between baseline and CDS sessions

- The GPs who expressed concerns about time took longer when using the CDS (mean time 15.45 min) than in the baseline session (mean time 13.53 min), paired samples t-test: 2.13, df = 12, P = 0.055, but this was not the case for the whole GP sample

- Despite concerns about time, GPs believed that they could become better using the CDS

Perception and objective measure of time

Impact on time: neither increase nor decrease

Driving perception: searching and selecting symptom codes takes longer than typing free text in patient notes as usual, limited time in consultations

Richardson et al. 2017 [118]

USA

To understand the determinants of usability of two CDS tools for lessons and themes that could be generalizable to all forms of CDS

Condition of focus: Upper Respiratory Tract Infections

Setting: General Practice

Tool: CDS for antibiotic ordering for URTIs, using a clinical prediction rule for risk assessment of either A Streptococcus, pharyngitis or pneumonia

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: Yes

Observational study

(1) Think aloud testing using written case scenario

(2) Near live testing using simulated patients

Visibility

Workflow

Content

Understandability

Navigation

Duration of each think aloud/near live scenario: 25—45 min

- the automatic order set, automatically generated documentation and communication with nurses and patients decreased workload and saved time

Passive alerts triggered at the time of decision making allow clinicians to use tools without disturbing their natural workflow

“I much prefer to have stuff in the background that doesn’t force me to have hard stops… There may be a whole series of other things I’m dealing with."

Perception

Impact on time: Decrease

Driving perception: can be used in such a way as to fit in with workflow and decision making

Richardson et al. 2019 [119]

USA

To further understand the barriers and facilitators of meaningful CDS usage within a real clinical context

Condition of focus: Upper Respiratory Tract Infections

Setting: General Practice

Tool: CDS for antibiotic ordering for URTIs, using a clinical prediction rule for risk assessment of either A Streptococcus, pharyngitis or pneumonia

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: Yes

Qualitative observational study

Tool Interruptions

Workflow

Tool Applicability

Patient-Tool interaction

Provider-Computer-Patient Interaction

Ease of Use

Missed Opportunities

- Of 6 patient encounters, 5 were acute or follow-up visits that lasted about 15 min each, 1 was a complete physical exam that was about 30 min in length

- Clinicians spent 0%-3% of visit time listening to the patient without engaging with the computer

- Clinicians completed the tool quickly; however, during half of the visits, hard stops and fixed elements in the tool created barriers. Clinicians spent about 1 min of the visit time completing the CDS tool

Objective measure (estimate) of time of whole consultations

Impact on time: neither increase nor decrease

Rubin et al. 2021 [16]

UK

To establish the tool's acceptability and collect relevant data to inform

the design of a subsequent definitive trial

Condition of focus: Cancer

Setting: General Practice

Tool: CDS risk assessment tool for oesophageal-gastric cancer

- Embedded/linked with EMR: No

- Interruptive alert: No, audit tool

- User-driven: Clinician

- Risk score: Yes

Randomised feasibility study

- Quantitative usage data

- Qualitative interviews

Quantitative

- Data related to tool use (symptoms entered and risk score generated)

- Individual patient data from EMR 6 months after the index consultation, including data on secondary care procedures and diagnoses

Qualitative

GP interviews re facilitators and constraints influencing

implementation of eCDS in routine practice

Use of eCDS by GPs was very low and only loosely consistent with use claimed during interviews

Problems with use were identified by all GPs interviewed

‘lack of integration of the software with the clinical systems’ (n = 7)

‘slow to access and/or use’ (n = 6)

‘You had to open up something completely separate to the clinical system that you’re working in, and when you’ve got very very limited time that was a negative almost pushing you to not using it’

S

Not enough time within consultations (n = 5)

- ‘Patients never come with one symptom or issue, they come with a few different things, and we won’t automatically think, out of three problems, one of them is related to a gastric or oesophageal cancer, erm, I’m not necessarily going into the tool’. (GP5)

- ‘No way on this planet any of the GPs under the pressure we were under(…)was going to use a separate program’

Perception

Impact on time: Increase

Driving perception: limited time in consultations, separateness from the clinical system, time needed for coding, and complexity of consultations

Scheitel et al. 2017 [120]

USA

To assess the impact of our clinical decision support tool on the efficiency and accuracy

of clinician calculation of cardiovascular risk and its effect on the delivery of guideline-consistent treatment recommendations

Condition of focus: Cholesterol management

Setting: Primary Care

Tool: Cardiovascular risk scores and guideline-based treatment recommendations

- Embedded/linked with EMR: Yes

- Interruptive alert: No, audit tool

- User-driven: Clinician

- Risk score: Yes

Quantitative:

- usage data

- survey data

Time spent making calculation and recommendation

Efficiency of clicks and key strokes making calculation and recommendation

Accuracy of calculation and recommendation

Survey Results

Without the tool, clinicians spent an average of 4 min and 21 s to calculate ASCVD score and a total of 5 min and 8 s to additionally determine care/treatment

With the tool, the clinicians spent 39 s to calculate ASCVD score and a total of 1 min and 31 s determine a recommendation for patient care

The clinicians saved 3 min and 42 s in calculating ASCVD score and a total of 3 min and 38 s in determining care/treatment. The time savings were statistically significant

Objective measure of time to use tool

Impact on time: Decrease of 3 min 38 s

Seol et al. 2021 [121]

USA

To assess the effectiveness and efficiency of intervention via CDS on pertinent asthma outcomes in a real-world primary care setting

Condition of focus: Asthma

Setting: Paediatric Primary Care

Tool: CDS for asthma guidance and prediction to predict risk of adverse events (A-GPS)

- Embedded/linked with EMR: Yes

- Interruptive alert: No, audit tool

- User-driven: Clinician

- Risk score: Yes

Quantitative: notes review and survey data

Primary: adverse event (AE) within 1 year (ED visit/hospitalisation for asthma or unscheduled visit for asthma requiring oral corticosteroid)

Secondary:-

- Clinician burden for reviewing and collecting clinical data from EMR for making a clinical decision

- Healthcare cost

- Asthma control status

- Timeliness of asthma follow up care after AE

A-GPS significantly reduced clinician burden for chart review for asthma management by 67%, with an estimated median time to review patient’s medical records of 3.5 min (IQR: 2–5) with A-GPS intervention vs. 11.3 min (IQR: 6.3–15) without A-GPS (P < 0.001). Average decrease within a person with A-GPS (vs. without A-GPS) was 7.3 min

Objective measure of time to use tool

Impact on time: Decrease of 7.3 min

Shillinglaw et al. 2012 [97]

USA

To examine US physicians’ awareness, use, and attitudes regarding global CHD risk assessment in

clinical practice, and how these vary by provider specialty

Condition of focus: Chronic Heart Disease

Setting: Primary Care

Tool: CHD risk assessment tools

- Embedded/linked with EMR: Range

- Interruptive alert: No

- User-driven: Clinician

- Risk score: Yes

Quantitative survey

Awareness of tools available to calculate CHD risk

Method and use of CHD risk assessment

Attitudes towards CHD risk assessment

Frequency of using CHD risk assessment to guide recommendations of aspirin, lipid-lowering and blood pressure (BP) lowering therapies for primary prevention

Reasons for not using CHD risk assessment:

- Among physicians who reported not using CHD risk assessment (N = 492), the reason with the highest mean importance rating was, “It is too time consuming"

- Family physicians rated this reason higher than general internists and cardiologists

Perception

Impact on time: Increase

Driving perception: limited time in consultations

Siaki et al. 2021 [122]

USA

To determine the feasibility of a web-based clinical decision support tool (CDST) using a renin-aldosterone system (RAS) classification matrix and drug sequencing algorithm to assist providers with the diagnosis and management of uncontrolled hypertension

Condition of focus: Hypertension

Setting: Primary Care

Tool: CDS using a renin-aldosterone system classification matrix and drug sequencing algorithm to support diagnosis and management of uncontrolled HTN

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: Clinician

- Risk score: No

Quantitative data on hypertension clinical measures + survey of clinicians

Primary:

1) BP rates of control

2) clinician management time using an electronic logbook

3) Satisfaction with the CDS

The fastest clinician averaged 10 min per patient. The slowest took 20.56 min

The overall average was 16.59 min (17.05% less time spent), saving 3.41 min per office visit avoided

Objective measure of time of whole consultations

Impact on time: Decrease

Takamine et al. 2021 [123, 124]

USA

To understand providers’ views on the opportunities, barriers, and facilitators of incorporating risk prediction to guide their use of cardiovascular preventive medicines

Condition of focus: Cardiovascular disease

Setting: Primary Care

Tool: CVD risk assessment tools

- Embedded/linked with EMR: Range

- Interruptive alert: No

- User-driven: Clinician

- Risk score: Yes

Qualitative interviews

Attitudes toward adoption of an ASCVD risk prediction-based approach

Key provider concerns

- Quantified risk goals vs a “whole patient” approach

- Validity of risk prediction

- Compatability with workflow

- Does adopting risk prediction add value?

The role of performance measurement

Compatability with workflow

- Given time pressures, concerns about workflow were common. 'You’re going to create a reminder in there, what else are you going to take off my plate?’

Cognitive burden

- A few mentioned cognitive burdens associated with switching to this novel method: it’s easier to treat an A1C down to a certain value than, “Well, if this person’s A1C is 7.5, the cardiovascular risk is a certain number, and if we get it down to 6.8, the cardiovascular risk is a different number.”’

Perception

Impact on time: Increase

Driving perception: limited time in consultations, time needed to calculate or search for risk numbers, adding work without reducing anything else

Wan et al. 2012 [125]

Australia

To evaluate the uptake and use of the CDS tool as well as to describe the impact of the EDS tool on the primary care consultation for diabetes from the perspectives of general practitioners and practice nurses

Condition of focus: Diabetes

Setting: General Practice

Tool: CDS to support management of patients with type 2 diabetes

- Embedded/linked with EMR: Yes

- Interruptive alert: Yes

- User-driven: Clinician

- Risk score: Yes

Qualitative interviews

Use of the CDS tool

Impact of the tool on the consultation process

Impact of the tool on diabetes care

Barriers to the use of the tool

Suggestions on its improvement

Impact on the consultation process

- GPs’ perceptions varied on the impact of the tool on consultation times. Many felt they tended to spend longer with patients when using the tool compared to usual consultations, but that this was because they were using the tool to provide better quality of care for their patients

- One PN felt the consultation was lengthened, and another reported no change

- Problems with tool functionality were perceived by some GPs as costing time. Some thought the tool itself slowed down their IT systems

- Some felt the tool was distracting when the patient wasn’t attending for diabetes care

Perception

Impact on time: mixed views

Driving perception: limited time in consultations, tool is time consuming and distracting, better quality care takes longer

Wright et al. 2020 [126]

New Zealand

To assess the acceptability and feasibility of the Maternity Case-finding Help Assessment Tool (MatCHAT), a tool designed to provide e-screening and clinical decision support for depression, anxiety, cigarette smoking, use of alcohol or illicit substances, and family violence among pre- and post-partum women under the care of midwives

Condition of focus: Perinatal mental health

Setting: Midwifery

Tool: CDS for screening for antenatal and postnatal depression, anxiety, substance use and partner violence

- Embedded/linked with EMR: No

- Interruptive alert: No

- User-driven: Clinician

- Risk score: Unclear

Mixed methods:

Quantitative usage data + qualitative interviews with midwives

MatCHAT usage data

- numbers of screens completed

- positive cases

- participants who wanted help and the

level of care recommended

- survey ratings of acceptability, feasibility and utility

Interviews

- the MatCHAT prototype

- midwives' knowledge

- barriers to implementation

Barriers to implementation

- midwives unanimous that MatCHAT was ‘one more thing’ in their hectic work schedule, and this influenced the low uptake

- The midwives who did not use MatCHAT thought that it would increase the length of appointments: ‘I was in conflict because I know I needed to ask those questions and MatCHAT would have been useful for that, but in another way, it was going to take up a large chunk of time.’

- midwives also worried that screening might ‘open a can of worms’

Perception

Impact on time: mixed views

Driving perception:

- increase: heavy workload and limited time, worry that tool would increase time, might 'open a can of woms'

- decrease: if used efficiently can cut overall time spent screening

Wu et al. 2013 [127]

US

To examine physicians' experiences of using MeTree, a computerized Family Health History CDS tool which includes risk stratification

Condition of focus: Family health history

Setting: Primary Care

Tool: a CDS tool to collect data on family health history and risk stratification for various conditions

Mixed methods:

Quantitative survey + qualitative interviews with physicians

Survey and interviews:

Ease of integration of MeTree into clinical practice at the two intervention clinics

Physicians initially felt that they were already collecting high-quality family histories and that MeTree would negatively impact workflow and redirect prioirities

However, post MeTree introduction, 86% of physicians believed that the tool improved the way they practised medicine, thereby making practice easier, and none reported that it adversely affected their workflow

Perception

Impact on workflow:

No negative impact

Driving perception: the tool improved the way they practised, making practice easier

Dexheimer et al. 2013 [128]

US

To examine whether an automatic disease detection system increases clinicians’ use of paper-based guidelines and decreases time to a disposition decision

Condition of focus: Asthma

Setting: Primary Care

Tool: a computerized asthma detection system combined with a paper-based asthma care protocol in the pediatric ED to help standardize care and reduce time to disposition decision

Quantitative data on time to disposition decision

Workload and efficiency outcomes assessed: time for disposition decision in the ED as the primary outcome

No effect from the use of eCDS on the time taken by the ED physicians to make a disposition decision

Objective measure of time

Impact on time: Neither increase or decrease

Moffat et al. 2014 [129]

UK

An evaluation my CRUK of cancer CDS tools

Condition of focus: Cancer

Setting: General Practice

Tool: eCDS using cancer risk algorithms with an interruptive risk score alert, risk calculator and audit function

Mixed methods:

Quantitative usage data of tool and referrals + qualitative interviews with GPs

Quantitative data: use of the tools in practice, referrals

Qualitative: impact on practice

and the management of patients, and considerations and implications for further work in this area

Interviews with GPs highlight the varying impact of the tools on practice, ranging from no impact at all, to increasing knowledge, to influencing the management, including referral or investigation, of patients

GPs were concerned about the level at which the prompt was set (i.e. at what level of risk a prompt appeared on their screen) and the potential for ‘prompt fatigue’

Some GPs expressed concerns that a 10-min consultation was a barrier to use of the symptom checker function within the tool

Perception

Impact on time: mixed views

Driving perception:

Increase: concern regarding risk threshold of the alert and lack of time within a 10-min appointment to use the tool

Decrease/no impact: Use of the tool did not influence the decision to investigate or refer in the majority of cases

Murphy et al. 2012 [130]

US

To measure the time spent by physicians managing asynchronous alerts

Condition of focus: generic

Setting: Primary Care

Tool: Asynchronous alerts during the day regarding a range of conditions

Quantitative: time spent processing alerts

 

On average, clinicians received over 56 alerts per day and spend 49 min responding to asynchronous alerts. These alerts burden clinicians in terms of physical fatigue and cognitive weariness. Providing clinicians with protected time to respond to alerts reduces alert-related workload and improves patient safety

Objective measure of time spent processing alerts

Impact on time: No conclusion