Real-world data in primary care: validation of diagnosis of atrial fibrillation in primary care electronic medical records and estimated prevalence among consulting patients’

Table 2 Predictive values, sensitivity, specificity, and agreement for a diagnosis of atrial fibrillation

	TP	FP	FN	TN	PPV (95% CI)	NPV (95% CI)	Sensitivity % (95% CI)	χ²p-value	Specificity % (95% CI)	χ²p-value	Diagnostic agreement kappa (95% CI)
Overall	407	11	9	410	97.37 (95.35–98.52)	97.85 (95.97–98.87)	97.84 (95.97–98.87)		97.39 (95.35–98.52)		0.952 (0.932–0.973)
Female	205	3	5	201	98.56 (95.85–99.51)	97.57 (94.45–98.96)	97.62 (94.45–98.96)	0.630^a	98.53 (95.85–99.51)	0.018^a	0.961 (0.935–0.988)
Male	202	8	4	209	96.19 (92.66–98.06)	98.12 (95.27–99.27)	98.06 (95.27–99.27)	0.630^a	96.31 (92.66–98.06)	0.018^a	0.943 (0.912–0.975)
Age < 70	87	6	1	95	93.55 (86.63–97.01)	98.96 (94.33–99.82)	98.86 (94.33–99.82)	0.467^a	94.06 (86.63–97.01)	0.146^a	0.926 (0.872–0.980)
Age ≥ 70	320	5	8	315	98.46 (96.45–99.34)	97.52 (95.19–98.74)	97.56 (95.19–98.74)	0.467^a	98.44 (96.46–99.34)	0.146^a	0.960 (0.938–0.981)

^aFisher’s exact test (two-sided); TP true positive, FP false positive, FN false negative, TN true negative, PPV positive predictive value, NPV negative predictive value, 95% CI 95% confidence interval

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