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Table 3 Most common reasons for 211 GPs not to co-prescribe a laxative with an opioid in total and for GPs scoring in the highest and lowest quartile of adherence

From: Adherence to coprescribing of laxatives with opioids and associated characteristics in general practices in the Netherlands

 

% of GPs with reason in top-3

Reason not to adhere to recommendation

All GPs (n = 211)

Score in lowest quartile of guideline adherence (n = 29)a

Score in highest quartile of guideline adherence (n = 25)a

Patient still has laxative

58.8

69.0

72.0

Patient does not want laxative

44.6

34.5

36.0

Contra-indication of laxative use

39.8

51.7

48.0

Patient cannot take laxative (e.g. palliative phase)

33.7

31.0

40.0

Intermitted opioid use (when needed)

28.0

24.1

32.0

Acute opioid use (e.g. transportation to ER)

22.3

24.1

20.0

GP will prescribe laxative later, if necessary

17.5

13.8

24.0

Patient will use over the counter laxative to prevent constipation

12.3

6.9

4.0

Very low dose of opioid

9.5

20.7

4.0

Adverse events of laxative

7.6

3.5

8.0

  1. aFrom a selection of 103 practices with both guideline adherence scores and information from the questionnaire