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Table 4 Achievement of treatment target (HbA1c < 7% or 53 mmol/mol) by the changes in use of glucose lowering medication

From: Mode of treatments and achievement of treatment targets among type 2 diabetes patients with different comorbidities – a register-based retrospective cohort study in Finland

 

Changes in the use of glucose lowering medication

Overall achievement of

treatment target

Intensification of medication

No change in medication

De-intensification of medication

Patient categories: a

    

T2D only

(n = 530)

(n = 2409)

(n = 111)

(n = 3050)

Proportion of patients undergoing changes in glucose medication, %

17.4

79.0

3.6

 

Target met 2011-12, %

83.0

74.0

93.7

76.3

Target met 2015-16, %

63.4

68.1

87.4

68.0

Change in achievement of treatment target (%)

-19.6

-5.9

-6.3

-8.3

T2D + CVD

(n = 363)

(n = 1493)

(n = 110)

(n = 1966)

Proportion of patients undergoing changes in glucose medication, %

18.5

75.9

5.6

 

Target met 2011-12, %

81.3

67.9

90.0

71.3

Target met 2015-16, %

63.4

60.4

89.1

62.6

Change in achievement of treatment target (%)

-17.9

-7.5

-0.9

-8.7

T2D + AMD

(n = 127)

(n = 508)

(n = 40)

(n = 675)

Proportion of patients undergoing changes in glucose medication, %

18.8

75.3

5.9

 

Target met 2011-12, %

88.2

68.7

95.0

73.9

Target met 2015-16, %

66.9

61.0

80.0

63.3

Change in achievement of treatment target (%)

-21.3

-7.7

-15.0

-10.6

T2D + CVD + AMD

(n = 57)

(n = 290)

(n = 32)

(n = 379)

Proportion of patients undergoing changes in glucose medication, %

15.0

76.5

8.4

 

Target met 2011-12, %

78.9

64.5

87.5

68.6

Target met 2015-16, %

56.1

59.0

84.4

60.7

Change in achievement of treatment target (%)

-22.8

-5.5

-3.1

-7.9

P-value b

0.683

0.835

0.157

0.712

  1. (a) Selection criteria of the patients: Age ≥ 20, alive by the end of 2016 and whose HbA1c measured both in 2011-12 and 2015-16 (n = 6070). (b) P-value for the differences in the changes in use of glucose lowering medication during the follow-up between different patient groups; logistic regression models with GEE. Adjustment for age and sex did not change the P-value. CVD = cardiovascular disease (I20-I25, I46, I48, I50, I63-I66 (except I63.6) and G45), AMD = any mental disorder (ICD-10 code F00-F03, F20-F48 & G30)