Patient data and DRP outcome according to renal function and number of medications | Total n = 109 | < 10 continuous medications (n = 66) | ≥10 continuous medications (n = 43) | P-value | GFR ≥45 ml/min n = 81 | GFR < 45 ml/min n = 28 | P-value |
---|---|---|---|---|---|---|---|
Age (years), median (range), mean | 79 (52–98), 79 | 80 (58–98), 79 | 79 (52–91), 79 | P = 0.816 | 77 (52–95), 77 | 84 (64–98), 83 | P < 0.001 |
Female, n (%) | 60 (55.0) | 36 (54.5) | 24 (55.8) | P = 0.896 | 45 (56) | 15 (54) | P = 0.856 |
GFR < 45 ml/min, n (%) | 28 (25.7) | 14 (21.2) | 14 (32.5) | P = 0.185 | – | – | |
Number of medications per patient, mean (range) | 12 (5–28) | 9 (5–19) | 15 (10–28) | P < 0.001 | 12 (5–28) | 13 (5–25) | P = 0.450 |
Number of continuous medications, mean (range) | 9 (3–20) | 7 (3–9) | 13 (10–20) | P < 0.0001 | 9 (3–20) | 10 (3–19) | P = 0.232 |
Number of medications as needed, mean (range) | 3 (0–11) | 2 (0–11) | 4 (0–10) | P = 0.002 | 3 (0–11) | 3 (0–10) | P = 0.723 |
Number of DRP, mean | 3.9 | 2.9 | 5.3 | 3.4 | 5.1 | ||
Number of DRP, median | 4 | 3 | 5 | P < 0.001 | 3 | 5 | P < 0.001 |