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Table 1 Health sector costs, including intervention costs, according to trial arm, in total sample and stratified by prognostic group

From: Economic evaluation of a Decision Support Tool to guide intensity of mental health care in general practice: the Link-me pragmatic randomised controlled trial

 

All participants

p value

Minimal/mild

p value

Severe

p value

prognostic group

prognostic group

Comparison, n

837

 

416

 

421

 

Intervention, n

834

 

414

 

420

 

6 months

 Mean cost (SD) [1]

  Comparison

$1,247 (4,473)

 

$304 (1,045)

 

$2,178 (6,057)

 

  Intervention

$2,231 (6,716)

 

$429 (1,150)

 

$4,006 (8,984)

 

Mean difference, Coef. (95% CI)

 Primary analysis [2]

$24 (9 to 44)

p < 0.0001

$28 (-5 to 79)

0.106

$340 (126 to 644)

p < 0.0001

 Sensitivity analysis [3]

$20 (6 to 40)

0.002

$20 (-4 to 60)

0.108

$227 (45 to 514)

0.009

 Sensitivity analysis [4]

$24 (7 to 46)

0.002

$17 (-2 to 50)

0.092

$320 (94 to 669)

0.002

 Sensitivity analysis [5]

$23 (9 to 42)

p < 0.0001

$29 (-3 to 78)

0.078

$287 (96 to 554)

0.001

12 months

 Mean cost (SD) [1]

  Comparison

$2,787 (9,879)

 

$640 (1,801)

 

$4,908 (13,498)

 

  Intervention

$3,871 (12,178)

 

$991 (2,448)

 

$6,710 (16,476)

 

Mean difference, Coef. (95% CI)

 Primary analysis [2]

$50 (10 to 102)

0.011

$59 (6 to 134)

0.025

$645 (-152 to 1,818)

0.128

 Sensitivity analysis [3]

$31 (9 to 64)

0.003

$31 (-15 to 114)

0.108

$366 (86 to 802)

0.005

 Sensitivity analysis [4]

$31 (8 to 62)

0.003

$23 (-10 to 82)

0.214

$492 (143 to 1,031)

0.002

 Sensitivity analysis [5]

$48 (8 to 99)

0.014

$59 (9 to 131)

0.018

$538 (-219 to 1,651)

0.19

 Sensitivity analysis [6]

$1 (-26 to 47)

0.974

-$3 (-39 to 59)

0.911

$242 (-1,261 to 3,673)

0.822

  1. SD Standard deviation, Coef. Estimated coefficient, CI Confidence interval
  2. [1] Estimated using multiple imputation. [2] Mean for intervention arm minus mean for comparison arm estimated using generalized linear models (gamma family, log link) adjusted for baseline K10 (all models) and prognostic group (model with all participants only). Estimated using multiple imputation. [3] Sensitivity analysis using complete cases only using generalized linear models (gamma family, log link) adjusted for baseline K10 (all models) and prognostic group (model with all participants only). [4] Same as [3] but adjusted for general practice. [5] Sensitivity analysis where care navigators spent 50% of time on care navigation. Data was multiply imputed prior to analysis. [6] Sensitivity analysis using participants with Medicare Benefits Schedule and Pharmaceutical Benefits Scheme data adding covariates of sex and holding a health care card. Only includes 466 participants providing consent to this data (n = 238 in comparison group, n = 228 in Intervention group)