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Table 4 A logistic regression analysis for predictors of ≥3% weight loss

From: Predictors for successful weight reduction during treatment with Dapagliflozin among patients with type 2 diabetes mellitus in primary care

  

Model 1

Model 2

OR (95% CI)

OR (95% CI)

Age

Per 1 year

0.99 (0.96–1.01)

1.01 (0.97–1.04)

Sex

Male

1(ref.)

1(ref.)

Female

0.84 (0.47–1.49)

1.08 (0.52–2.24)

BMI

Q1

1(ref.)

1(ref.)

Q2

0.92 (0.42–2.04)

0.72 (0.29–1.76)

Q3

1.36 (0.60–3.07)

0.73 (0.30–1.76)

Q4

1.33 (0.60–2.96)

1.14 (0.47–2.81)

Alcohol consumption

Heavy drinkera (−)

1(ref.)

1(ref.)

Heavy drinkera (+)

1.39 (0.75–2.57)

1.35 (0.65–2.80)

Smoking status

Non-smoker

1 (ref)

1(ref.)

Current smoker

1.23 (0.61–2.44)

1.09 (0.46–2.55)

Regular exerciseb

No

1 (ref)

1(ref.)

Yes

2.01 (1.07–3.79)

2.16 (1.07–4.36)

Hypertension

No

1 (ref)

1(ref.)

Yes

0.99 (0.51–1.91)

0.90 (0.42–1.90)

Dyslipidemia

No

1 (ref)

1(ref.)

Yes

0.63 (0.21–1.86)

0.65 (0.20–2.09)

CVD

No

1 (ref)

1(ref.)

Yes

1.62 (0.31–8.58)

1.69 (0.23–12.30)

Metformin

No

1 (ref)

1(ref.)

Yes

1.48 (0.75–2.93)

2.90 (1.23–6.80)

Sulfonylurea

No

1 (ref)

1(ref.)

Yes

0.60 (0.34–1.08)

0.39 (0.19–0.79)

Renal function

eGFR < 60 mL/min/1.73 m2

1 (ref)

1(ref.)

eGFR ≥60 mL/min/1.73 m2

8.29 (0.95–72.34)

13.84 (1.33–144.26)

  1. Values were calculated by multivariable linear regression analyses
  2. Model 1 was unadjusted
  3. Mod1 2 was adjusted for age, sex, BMI, alcohol consumption status, smoking status, physical activity, hypertension, dyslipidemia, CVD, metformin, sulfonylurea, and renal function
  4. aHeavy drinker was defined as men who consumed ≥2 drinks per day or women who consumed ≥1 drink per day
  5. bRegular exercise was defined as exercising three or more times per week
  6. Abbreviations: OR Odds ratio, CI Confidence interval, BMI Body mass index, CVD Cardiovascular disease, GFR Glomerular filtration rate
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