Table 2 Type of newly prescribed treatment and reason for GP consultation among colorectal cancer and matched cancer-free controls in the 6 months before index date, stratified by tumour site
Proximal | Distal | Rectum | ||||
|---|---|---|---|---|---|---|
Cases | Cancer-free controls | Cases | Cancer-free controls | Cases | Cancer-free controls | |
N = 1,910 n (%) | N = 7,640 n (%) | N = 2,022 n (%) | N = 8,088 n (%) | N = 1,926 n (%) | N = 7,704 n (%) | |
Common newly prescribed medication | ||||||
A06AD | ||||||
Osmotically acting laxatives | 729 (38) | 175 (2) | 928 (46) | 194 (2) | 914 (48) | 173 (2) |
A06AB | ||||||
Contact laxatives | 260 (14) | 32 (< 0.5) | 426 (21) | 47 (1) | 444 (23) | 36 (1) |
A02BC | ||||||
Proton pump inhibitors | 288 (15) | 373 (5) | 182 (9) | 377 (5) | 143 (7) | 337 (4) |
B03AA | ||||||
Iron bivalent, oral preparations | 273 (14) | 32 (< 0.5) | 71 (4) | 42 (1) | 31 (2) | 25 (< 0.5) |
A06AG | ||||||
Enemas | 40 (2) | 22 (< 0.5) | 117 (6) | 35 (< 0.5) | 50 (3) | 23 (< 0.5) |
M01AB | ||||||
Acetic acid derivatives and related substances | 116 (6) | 303 (4) | 106 (5) | 300 (4) | 76 (4) | 323 (4) |
Common reason for GP consultation | ||||||
D75 | ||||||
Malignant neoplasm colon/rectum | 664 (35) | 1 (< 0.5) | 780 (39) | 2 (< 0.5) | 860 (45) | 0 (0) |
D16 | ||||||
Rectal bleeding | 10 (1) | 13 (< 0.5) | 94 (5) | 11 (< 0.5) | 78 (4) | 12 (< 0.5) |
B80 | ||||||
Iron deficiency anaemia | 99 (5) | 9 (< 0.5) | 27 (1) | 10 (< 0.5) | 15 (1) | 2 (< 0.5) |
B82 | ||||||
Anaemia other/unspecified | 64 (3) | 11 (< 0.5) | 12 (1) | 10 (< 0.5) | 9 (1) | 12 (< 0.5) |
D06 | ||||||
Abdominal pain localized other | 44 (2) | 21 (< 0.5) | 41 (2) | 37 (1) | 9 (1) | 14 (< 0.5) |