Baseline | Follow-Up | Change | p | padj b | |
---|---|---|---|---|---|
Adverse drug reaction | 8.5 ± 22.0 | 4.2 ± 4.7 | -50.5% | 0.054 | 0.157 |
Total gastrointestinal tract | 17.6 ± 19.7 | 10.0 ± 13.4 | -43.0% | 0.001 | 0.041 |
Lipid metabolism disorder | 22.0 ± 37.3 | 13.7 ± 24.1 | -37.6% | 0.059 | 0.156 |
Lower gastrointestinal tract | 11.7 ± 15.2 | 7.4 ± 14.6 | -36.9% | 0.038 | 0.157 |
Weight/dietary problems | 19.5 ± 45.6 | 12.3 ± 35.3 | -36.8% | 0.205 | 0.397 |
Upper gastrointestinal tract | 16.1 ± 16.1 | 10.2 ± 11.5 | -36.5% | 0.003 | 0.041 |
Vertigo | 11.5 ± 12.2 | 7.4 ± 7.3 | -35.7% | 0.004 | 0.027 |
Spinal disorders | 34.8 ± 29.1 | 22.8 ± 28.4 | -34.6% | 0.003 | 0.028 |
High blood pressure | 40.0 ± 45.8 | 26.9 ± 44.1 | -32.8% | 0.037 | 0.176 |
Somatoform disorders | 22.3 ± 26.2 | 15.3 ± 23.7 | -31.6% | 0.043 | 0.156 |
General fatigue and weakness | 20.0 ± 19.4 | 13.7 ± 14.1 | -31.5% | 0.008 | 0.047 |
Lymph/leg oedema, chronic wounds | 6.9 ± 9.2 | 5.0 ± 7.2 | -28.1% | 0.090 | 0.218 |
Coronary heart disease | 16.4 ± 21.5 | 12.0 ± 35.2 | -26.7% | 0.279 | 0.477 |
Congestive heart failure | 12.1 ± 16.9 | 8.9 ± 16.7 | -26.3% | 0.175 | 0.390 |
Cardiac arrhythmia | 12.0 ± 18.5 | 9.3 ± 10.0 | -22.3% | 0.194 | 0.402 |
Dementia | 8.4 ± 15.3 | 6.8 ± 11.8 | -19.2% | 0.393 | 0.569 |
Diabetes mellitus (all types) | 21.9 ± 26.3 | 17.7 ± 27.6 | -19.2% | 0.263 | 0.477 |
Thyroid disorder | 10.2 ± 17.3 | 9.5 ± 23.4 | -6.0% | 0.832 | 0.862 |
Arthrosis of the large joints | 9.6 ± 9.2 | 9.7 ± 14.1 | 1.9% | 0.914 | 0.914 |
Shoulder pain | 6.6 ± 6.7 | 6.9 ± 9.0 | 5.2% | 0.756 | 0.812 |
Acute infections of the respiratory tract | 40.2 ± 39.1 | 42.6 ± 45.9 | 5.9% | 0.686 | 0.795 |
Mild mental disorders | 15.3 ± 18.5 | 16.5 ± 28.2 | 7.5% | 0.730 | 0.814 |
Headache | 9.2 ± 9.3 | 10.3 ± 13.6 | 11.9% | 0.497 | 0.626 |
Urinary tract infection | 5.8 ± 4.4 | 6.7 ± 7.6 | 15.4% | 0.296 | 0.476 |
Chronic obstructive pulmonary disease | 7.3 ± 9.1 | 8.7 ± 15.3 | 19.5% | 0.420 | 0.580 |
Family, partnership problems | 9.1 ± 16.2 | 11.2 ± 22.2 | 24.0% | 0.421 | 0.555 |
Chronic kidney disease | 5.7 ± 15.4 | 7.1 ± 21.2 | 24.5% | 0.588 | 0.711 |
Asthma | 6.3 ± 9.9 | 8.1 ± 15.0 | 27.4% | 0.326 | 0.497 |
Workplace issues, unemployment | 7.0 ± 9.3 | 13.3 ± 30.3 | 90.2% | 0.045 | 0.144 |