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Table 3 FIT sensitivities/specificities at various Hb cut offs and modelling data for high-risk polyps

From: Cost effectiveness of using Faecal Immunochemical Testing (FIT) as an initial diagnostic investigation for patients with lower gastrointestinal symptoms suggestive of malignancy

Hb Threshold Sensitivity 95% CI Specificity 95% CI True +  True - False +  False - PPV (%) NPV (%)
4 μg 71.2 60.5–87.2 79.8 59.7–88.1 29 1895 503 11 6 99.2
10 μg 68.9 53.2–81.4 80.2 76.1–83.7 29 1895 468 13 7 99.2
15 μg 66.7 50.9–79.6 83.1 79.2–86.5 29 1895 385 14 7 99.3
20 μg 64.4 48.7–77.7 85.7 81.9–88.7 29 1895 316 16 8 99.1