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Table 2 FIT sensitivities/specificities at various Hb cut offs and modelling data for CRC

From: Cost effectiveness of using Faecal Immunochemical Testing (FIT) as an initial diagnostic investigation for patients with lower gastrointestinal symptoms suggestive of malignancy

Hb Threshold

Sensitivity

95% CI

Specificity

95% CI

True + 

True -

False + 

False -

PPV (%)

NPV (%)

4 μg

97.2

85.5–99.9

88.4

58.1–92.7

26

1895

258

0.8

2

99.9

10 μg

92.1

86.9–95.3

85.8

78.3–90.1

26

1895

314

2

7.5

99.8

15 μg

92.3

86.6–96.1

86.9

85.6–88.1

26

1895

286

2

8.2

99.8

20 μg

89.5

84.9–93.1

86.6

85.4–87.7

26

1895

293

3

8

99.8

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BMC Primary Care

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