Table 1 Baseline clinical characteristics of patients diagnosed with bone metastases or multiple myeloma (n = 586)

 Age at presentation (years)

0

(0)

62.4

±9.2

63.2

±9.9

0.417

  Male

0

(0)

75

(55.2)

253

(56.2)

0.844

  Female

61

(44.8)

197

(43.8)

  No plain film (n, %)

0

(0)

47

(34.6)

204

(45.3)

< 0.001

  Osteolytic lesion (n, %)

89

(65.4)

146

(32.4)

  Osteoblastic lesion (n, %)

0

(0)

40

(8.9)

  Mixed lytic-blastic lesion (n, %)

0

(0)

60

(13.3)

  Hemoglobin (g/dL)

39

(6.7)

9.37

±2.36

11.17

±2.16

< 0.001

  Hematocrit (mg %)

44

(7.5)

28.86

±7.48

34.48

±6.38

< 0.001

  Blood urea nitrogen (mg/dL, median (IQR))

52

(8.9)

19

(12, 30)

14

(11, 21)

< 0.001

  Serum creatinine (mg/dL, median (IQR))

44

(7.5)

1.3

(0.8, 2.3)

0.9

(0.7, 1.2)

< 0.001

  Serum calcium (mg/dL)

146

(24.9)

9.81

±1.64

9.21

±1.28

< 0.001

  Total protein (g/dL)

66

(11.3)

8.82

±2.60

6.96

±0.97

< 0.001

  Serum albumin (g/dL)

57

(9.7)

3.10

±0.88

3.42

±0.68

< 0.001

  Serum globulin (g/dL)

63

(10.8)

5.66

±3.05

3.56

±1.01

< 0.001

  Albumin/Globulin ratio

63

(10.8)

0.80

±0.61

1.04

±0.35

< 0.001

  Alkaline phosphatase (U/L, median (IQR))

72

(12.3)

86

(63, 120)

138

(96, 262)

< 0.001

  Lactate dehydrogenase (U/L, median (IQR))

511

(86.9)

201

(142, 245)

239

(178, 347)

0.060