Table 3 Factors associated with prescription of antibiotics to children with AOM in Danish general practice
From: Prescription of antibiotics to children with acute otitis media in Danish general practice
Variable | ORcrude [95% CI] | Model 1 ORadj [95% CI] | Model 2 ORadj [95% CI] | Model 3 ORadj [95% CI] | Model 4 ORadj [95% CI] |
|---|---|---|---|---|---|
N | 278 | 278 | 278 | 278 | 263 |
Patient Variables | |||||
Gender | |||||
Girls | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
Boys | 0.86 [0.50–1.49] | 0.67 [0.35–1.26] | 0.75 [0.38–1.46] | 0.77 [0.41–1.43] | 0.81 [0.41–1.60] |
Age | |||||
< 2 years | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) | 1 (reference) |
≥ 2 years | 0.63 [0.36–1.10] | 0.79 [0.43–1.45] | 0.85 [0.45–1.61] | 0.76 [0.41–1.43] | 0.82 [0.43–1.58] |
Symptoms | |||||
Symptom duration ≤3 days | 0.63 [0.37–1.09] | 0.71 [0.39–1.32] | 0.70 [0.37–1.30] | 0.66 [0.34–1.26] | 0.74 [0.38–1.45] |
Symptom worsening | 0.96 [0.45–2.03] | 0.67 [0.28–1.58] | 0.65 [0.28–1.52] | 0.66 [0.28–1.56] | 0.78 [0.31–1.98] |
Fever (temp. > 38.5 °) | 3.47 [1.98–6.07] | 3.69 [1.93–7.05] | 4.01 [2.01–8.00] | 3.95 [2.02–7.72] | 3.72 [1.87–7.40] |
Purulent ear secretion | 1.84 [0.88–3.87] | 2.35 [1.01–5.50] | 2.39 [0.98–5.79] | 2.10 [0.91–4.88] | 1.96 [0.84–4.58] |
Ear/face pain | 0.57 [0.31–1.03] | 0.79 [0.41–1.53] | 0.77 [0.39–1.53] | 0.71 [0.36–1.40] | 0.82 [0.40–1.64] |
Clinical Findings | |||||
Poor general condition | 4.02 [1.65–9.81] | 3.12 [1.31–7.46] | 2.91 [1.20–7.03] | 2.87 [1.20–6.88] | 2.62 [1.07–6.39] |
Tympanometry performed | 1.33 [0.77–2.29] | 1.36 [0.76–2.42] | 1.74 [0.94–3.22] | 1.33 [0.74–2.37] | 1.30 [0.70–2.40] |
Other | |||||
Parent request for antibiotics | 2.12 [0.46–9.75] | 1.41 [0.30–6.64] | 1.43 [0.30–6.92] | 1.16 [0.26–5.29] | 1.33 [0.28–6.36] |
GP Variables | |||||
Region | |||||
Northern Denmark | 1.28 [0.73–2.26] | 1 (reference) | |||
Southern Denmark | 1.21 [0.68–2.15] | 1.08 [0.51–2.29] | |||
Central Denmark | 0.61 [0.34–1.09] | 0.56 [0.28–1.12] | |||
Gender | |||||
Female | 1.73 [0.99–3.02] | 1 (reference) | |||
Male | 0.58 [0.33–1.01] | 0.53 [0.27–1.06] | |||
Age | |||||
< 50 | 0.88 [0.50–1.54] | 1 (reference) | |||
≥ 50 | 1.14 [0.65–1.98] | 1.84 [0.90–3.77] | |||
Practice rate of antibiotic prescribing for RTIs overall | |||||
p (25) lowest | 0.73 [0.39–1.37] | 1 (reference) | |||
p(25)-p(75) | 0.62 [0.36–1.07] | 1.05 [0.50–2.20] | |||
p(75) highest | 2.41 [1.26–4.62] | 2.85 [1.07–7.60] | |||
Practice rate of antibiotic prescribing for AOM | |||||
p (25) lowest | 0.26 [0.15–0.47] | 1 (reference) | |||
p(25)-p(75) | 1.91 [1.05–3.46] | 2.93 [1.45–5.94] | |||
p(75) highest | 2.09 [1.07–4.08] | 4.15 [1.82–9.47] | |||
Pseudo R2 | N/A | 0.1254 | 0.1512 | 0.1516 | 0.1716 |
Mean VIF | N/A | 1.11 | 1.17 | 1.23 | 1.16 |