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Table 2 Sensitivity, specificity, PPV, and NPV of the FRS model for the prediction of 10-year hCHD

From: Performance of the Framingham coronary heart disease risk score for predicting 10-year cardiac risk in adult United Arab Emirates nationals without diabetes: a retrospective cohort study

Cut-off predicted risk threshold, %

Sensitivity, % (SE)

Specificity, % (SE)

PPV, % (SE)

NPV, % (SE)

≥ 20

36.9 (9.9)

94.4 (1.4)

25.2 (7.9)

96.7 (0.8)

≥ 10

60.9 (10.1)

82.7 (2.3)

15.3 (3.8)

97.6 (0.8)

≥ 7.5*

73.8 (9.2)

76.7 (2.6)

14.0 (3.2)

98.3 (0.7)

  1. PPV, positive predictive value; NPV, negative predictive value; FRS, Framingham risk score; hCHD, hard coronary heart disease; SE, standard error; ROC, receiver operating characteristic
  2. *Optimal cutoff-point determined by ROC curve analysis