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Table 1 Baseline predictors and outcomes in the Emirati validation and Framingham cohorts

From: Performance of the Framingham coronary heart disease risk score for predicting 10-year cardiac risk in adult United Arab Emirates nationals without diabetes: a retrospective cohort study

Characteristic

Emirati validation cohort (n = 554)

Framingham study cohort* (n = 5251)

P-value†

Age (years), mean (SD)

48.0 (12.8)

49.0 (NA)

 

Men, n (%)

249 (44.9)

2439 (46.4)

0.502

Blood pressure, n (%)

 Normal and prehypertension

408 (73.7)

3558 (67.7)

<  0.001

 Stage 1 HTN

116 (20.9)

1095 (20.9)

 

 Stage 2 HTN

30 (5.4)

598 (11.4)

 

TC, mmol/L, n (%)

  < 5.17

298 (53.8)

1996 (38.0)

<  0.001

 5.17–6.18

166 (30.0)

1879 (35.8)

 

  ≥ 6.20

90 (16.2)

1376 (26.2)

 

HDL-C, mmol/L, n (%)

  ≤ 1.53

482 (87.0)

3829 (72.9)

<  0.001

  ≥ 1.55

72 (13.0)

1422 (27.1)

 

Smoking history, n (%)

102 (18.4)

2045 (38.9)

<  0.001

Diabetes mellitus, n (%)

0 (0.0)‡

234 (4.5)

<  0.001

Observed hCHD events, n (%)

26 (4.7)

273 (5.2)

 
  1. NA, not available; HTN, hypertension; TC, total cholesterol; HDL-C, high-density lipoprotein-cholesterol; hCHD, hard coronary heart disease; SD, standard deviation; FRS, Framingham risk score
  2. *Data retrieved from D’Agostino et al. [10]
  3. P-values for categorical variables were calculated using Fisher’s exact test (2-tailed)
  4. ‡The FRS hCHD model is not intended for patients with diabetes, therefore excluded from the study