Skip to main content

Table 4 Symptoms reported by patients and doctors when a faecal immunochemical test (FIT) was requested in primary care, stratified for outcome

From: Patient-reported and doctor-reported symptoms when faecal immunochemical tests are requested in primary care in the diagnosis of colorectal cancer and inflammatory bowel disease: a prospective study

 

FIT

Significant colorectal disease

CRC or IBD

Symptom (n)

With symptom

FIT positive (%)

Sign CRD, total

Symptom + no sign CRD (% of total without CRD)

Symptom + sign CRD (% of total with CRD)

p

CRC or IBD, total

Symptom + no CRC or IBD (% of total without CRC/IBD)

Symptom + CRC or IBD (% of total with CRC/IBD)

p

Abdominal pain

 Patient (364)

220a

74 (33.6)

27

206 (61.1)

14 (51.9)

0.46

19

210 (60.9)

10 (52.6)

0.64

 Doctor (350)

201

58 (28.9)

26

187 (57.7)

14 (53.8)

0.86

18

193 (58.1)

8 (44.4)

0.37

Diarrhoea

 Patient (361)

173a

63 (36.4)

27

157 (47.0)

16 (59.3)

0.31

19

160 (46.8)

13 (68.4)

0.11

 Doctor (342)

151

54 (35.8)

26

134 (42.4)

17 (65.4)

0.04

18

139 (42.9)

12 (66.7)

0.08

Urgency

 Patient (360)

146a

56 (38.4)

26

133 (39.8)

13 (50.0)

0.42

19

135 (39.6)

11 (57.9)

0.18

 Doctor (321)

72

30 (41.7)

23

64 (21.5)

8 (34.8)

0.23

16

66 (21.6)

6 (37.5)

0.21

Constipation

 Patient (359)

147a

52 (35.4)

26

134 (40.2)

13 (50.0)

0.44

19

138 (40.6)

9 (47.4)

0.73

 Doctor (340)

94

29 (30.9)

26

89 (28.3)

5 (19.2)

0.44

18

91 (28.3)

3 (16.7)

0.42

Incomplete evacuation

 Patient (361)

162a

59 (36.4)

26

149 (44.5)

13 (50.0)

0.73

19

153 (44.7)

9 (47.4)

1.00

 Doctor (308)

55

20 (36.4)

22

52 (18.2)

3 (13.6)

0.78

14

55 (18.7)

0

0.08

Reflux symptoms

 Patient (362)

76a

21 (27.6)

27

73 (21.8)

3 (11.1)

0.29

19

74 (21.6)

2 (10.5)

0.39

 Doctor (306)

44

9 (20.5)

21

40 (14.0)

4 (19.0)

0.52

15

43 (14.8)

1 (6.7)

0.71

Change in bowel habits

 Patient (342)

164

55 (33.5)

26

150 (47.5)

14 (53.8)

0.67

19

154 (47.7)

10 (52.6)

0.85

 Doctor (346)

158

60 (38.0)

26

144 (45.0)

14 (53.8)

0.51

18

149 (45.4)

9 (50.0)

0.89

Rectal bleeding

 Patient (347)

151

62 (41.1)

27

132 (41.3)

19 (70.4)

0.006

19

136 (41.5)

15 (78.9)

0.003

 Doctor (336)

91

43 (47.3)

24

79 (25.3)

12 (50.0)

0.02

17

80 (25.1)

11 (64.7)

0.001

Black faeces

 Patient (338)

72

30 (41.7)

27

66 (21.2)

6 (22.2)

1.00

19

68 (21.3)

4 (21.1)

1.00

 Doctor (337)

20

11 (55.0)

26

17 (5.5)

3 (11.5)

0.19

18

19 (6.0)

1 (5.6)

1.00

Weight loss

 Patient (343)

65

29 (44.6)

27

57 (18.0)

8 (29.6)

0.22

19

58 (17.9)

7 (36.8)

0.06

 Doctor (333)

45

20 (44.4)

24

42 (13.6)

3 (12.5)

1.00

16

43 (13.6)

2 (12.5)

1.00

  1. aModerate discomfort or more
  2. P value was calculated with Pearson’s Chi-square test or Fisher’s exact test
  3. Significant colorectal disease: Colorectal cancer, adenomas with high-grade dysplasia, adenomas with low-grade dysplasia ≥1 cm, inflammatory bowel disease
  4. CRC colorectal cancer. IBD inflammatory bowel disease. CRD colorectal disease