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Table 1 Descriptive characteristic of osteoarthritic patients and General Practitioners and Defined Daily Dose (DDD) during the year preceding the study period

From: A cluster randomized trial to measure the impact on nonsteroidal anti-inflammatory drug and proton pump inhibitor prescribing in Italy of distributing cost-free paracetamol to osteoarthritic patients

 

Experimental arm

Control arm

N (%)

N (%)

General Practitioners (GPs)

8

7

Sex

 F

1 (12.5)

3 (42.9)

 M

7 (87.5)

4 (57.1)

Number of patients

 Mean

7.3

8.4

 Range

(1–20)

(4–17)

Patients

58

59

Sex

 F

46 (79.3)

49 (83.1)

 M

12 (20.7)

10 (16.9)

Age

 Mean

79.6

78.5

 Range

(65–95)

(65–97)

Age classes

 65–74

15 (25.9)

16 (27.1)

 75–84

27 (46.6)

30 (50.8)

 85+

16 (27.6)

13 (22.0)

Prescription during the year before randomization

NSAIDs

 Users

27 (46.6)

28 (47.5)

 Total DDD in the period

2328.7

1030.6

DDD per patient, median (IQR)

40 (20–80)

26.5 (13.9–60)

 Average DDD per day

6.38

2.82

DDD per day per patient, median (IQR)

0.11 (0.05–0.22)

0.07 (0.04–0.16)

Opioids

 Users

16 (27.6)

22 (37.3)

 Total DDD in the period

627.0

521.4

DDD per patient, median (IQR)

14.5 (4–37.2)

8 (4–20)

 Average DDD per day

1.72

1.43

DDD per day per patient, median (IQR)

0.04 (0.01–0.10)

0.02 (0.01–0.05)

PPIs

 Users

28 (48.3)

27 (45.8)

 Total DDD in the period

4249.0

3719.3

DDD per patient, median (IQR)

119 (28–203)

133 (42–182)

Average DDD per day

11.64

10.19

DDD per day per patient, median (IQR)

0.33 (0.08–0.56)

0.36 (0.12–0.50)

  1. PPIs Proton Pump Inhibitors, NSAIDs Non-steroidal Anti-Inflammatory Drugs, DDD Defined Daily Dose, IQR interquartile range