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Table 2 Therapy- and Patient-Related Factors of the Participants of the Study according to their Self-Reported Measure of Medication Adherence, n = 299

From: Adherence to treatment and related factors among patients with chronic conditions in primary care: a cross-sectional study

Factors Total n (%) Adherent n (%) Poor Adherent n (%) Bivariate Analyses
n = 299 n = 166 n = 133 Crude OR 95% CI p-value
Therapy-Related
Number of prescriptions, mean ± SD 3.90 ± 2.2 3.94 ± 2.2 3.85 ± 2.3 1.02 (0.92 to 1.13) 0.725
Number of pills, mean ± SD 4.36 ± 2.9 4.26 ± 2.9 4.50 ± 3.0 0.97 (0.90 to 1.05) 0.482
Medication through injections
  Using injections 33 (11.0) 18 (10.8) 15 (11.3) Ref. Ref.  
  Not using injections 266 (89.0) 148 (89.2) 118 (88.7) 1.05 (0.51 to 2.16) 0.905
Therapy through inhalers
  Using inhalers 28 (9.4) 14 (8.4) 14 (10.5) Ref. Ref.  
  Not using inhalers 271 (90.6) 152 (91.6) 119 (89.5) 1.28 (0.59 to 2.78) 0.538
Interfering with Activities of Daily Living
  Interfering 27 (9.03) 10 (6.0) 17 (12.8) Ref. Ref.  
  Not-interfering 272 (91.0) 156 (94.0) 116 (87.2) 2.29 (1.01 to 5.18) 0.047
Patient-Related
Functional Independency of Daily Living Activities
  Independent 234 (78.3) 127 (76.5) 107 (80.5) Ref. Ref.  
  Slightly dependent 49 (16.4) 29 (17.5) 20 (15.0) 1.22 (0.65 to 2.28) 0.530
  Moderately dependent 16 (5.4) 10 (6.0) 6 (4.5) 1.40 (049 to 3.99) 0.524
  Severely dependent 0 (0) 0 (0) 0 (0)
  Totally dependent 0 (0) 0 (0) 0 (0)
Medication Dosing Reminders
  Not using any reminder 85 (28.4) 27 (16.3) 58 (43.6) Ref. Ref.  
  Use of alarms/phones/pillboxes 80 (26.8) 50 (30.1) 30 (22.6) 3.58 (1.88 to 6.81) < 0.001
  Association of medication with daily routines 134 (44.8) 89 (53.6) 45 (33.8) 4.25 (2.38 to 7.59) < 0.001
Patient’s Knowledge about Medication Regimen
  Not having an adequate knowledge 173 (57.9) 75 (45.2) 98 (73.7) Ref. Ref.  
  Having an adequate knowledge 126 (42.1) 91 (54.8) 35 (26.3) 3.40 (2.08 to 5.56) < 0.001
Perceived Overmedication in the Treatment
  Perception of overmedication 26 (8.7) 12 (7.2) 14 (10.5) Ref. Ref.  
  Not-perception of overmedication 273 (91.3) 154 (92.8) 119 (89.5) 1.51 (0.67 to 3.39) 0.317
Self-Perceived Quality of Life
  Not having good quality of life 153 (51.2) 76 (45.8) 77 (57.9) Ref. Ref.  
  Having good quality of life 146 (48.8) 90 (54.2) 56 (42.1) 1.63 (1.03 to 2.58) 0.038
  1. Abbreviations: CI, confidence interval; OR, odds ratio; SD, standard deviation; Ref., reference
  2. Bold values are statistically significant at p-values ≤0.05