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Table 1 Evidence summary [17] of cognitive tests for MCI (MCI versus normal cognition, dementia not included)

From: How to choose the most appropriate cognitive test to evaluate cognitive complaints in primary care

Test

Studies (n)

Test time (min)

Cut-off score

Study population, % MCI

Number of participants analysed

Sens (95% CI)

Spec (95% CI)

PPV (95% CI)

NPV (95% CI)

CDT

3

1–3

≤ 9

48

465

41 (34, 47)

83 (78, 88)

69 (60, 77)

60 (55, 65)

  

≤ 9

15

3198

58 (54, 63)

57 (55, 59)

19 (17, 22)

89 (87, 90)

  

≤ 9

14

428

69 (56, 81)

63 (58, 68)

23 (17, 30)

93 (89, 96)

MMSE

2

7–10

< 28

84

91

47 (36, 59)

73 (45, 92)

90 (76, 97)

22 (11, 35)

  

< 28

44

524

45 (39, 52)

80 (75, 84)

64 (56, 71)

66 (60,70)

MoCA

2

10

< 26

24

152

100 (91, 100)

50 (41,59)

39 (29, 50)

100 (94, 100)

  

< 26

20

99

80 (56, 94)

76 (65, 85)

46 (29, 63)

94 (85, 98)

  1. Only the studies reporting a cut-off score that was studied more than once are depicted in the table. Abbreviations: CI=Confidence Interval, MCI Mild Cognitive Impairment, NR Not Reported, Sens Sensitivity, Spec Specificity, NPV Negative Predictive Value, PPV Positive Predictive Value, AUC Area Under the Curve. Abbreviations cognitive tests: CDT ClockDrawing Test, MMSE Mini Mental State Examination, MoCA Montreal Cognitive Assessment