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Table 4 Associations between disease status and all-cause mortality in participants attending both HUNT2 (1995–97) and HUNT3 (2006–08)

From: Mortality in persons with undetected and diagnosed hypertension, type 2 diabetes, and hypothyroidism, compared with persons without corresponding disease - a prospective cohort study; The HUNT Study, Norway

 

HR (95% CI)

Disease statuses

Person-yearsa

Deathsa

Model 1b

Model 2b

Hypothyroidism women

 No

145,398

591

1.00

1.00

 Undetected

2219

6

0.94 (0.57–1.54)

0.55 (0.25–1.23)

 Diagnosed during follow-up

16,201

50

1.09 (0.87–1.36)

0.98 (0.73–1.31)

 Diagnosed baseline

10,142

51

1.30 (1.04–1.61)

1.27 (0.95–1.69)

Hypothyroidism men

 No

78,193

543

1.00

1.00

 Undetected

966

10

0.78 (0.46–1.30)

0.68 (0.36–1.28)

 Diagnosed during follow-up

4081

33

1.00 (0.72–1.37)

1.09 (0.77–1.56)

 Diagnosed baseline

1060

13

1.10 (0.67–1.80)

1.27 (0.73–2.21)

Type 2 diabetes mellitus

 No

205,330

830

1.00

1.00

 Undetected

9272

97

1.62 (1.36–1.94)

1.60 (1.30–1.98)

 Diagnosed during follow-up

20,018

173

1.33 (1.16–1.52)

1.29 (1.09–1.53)

 Diagnosed baseline

6129

91

1.84 (1.55–2.19)

1.96 (1.57–2.44)

Hypertension

 No

292,257

594

1.00

1.00

 Undetected

101,212

417

0.96 (0.86–1.06)

0.95 (0.84–1.08)

 Diagnosed during follow-up

85,004

597

1.12 (1.01–1.24)

1.16 (1.03–1–30)

 Diagnosed baseline

59,097

588

1.28 (1.16–1.42)

1.32 (1.17–1.49)

  1. HUNT The HUNT Study, HR hazard ratio, CI confidence interval
  2. aParticipants with missing data in fully adjusted analyses excluded
  3. bModel 1; adjusted for age. Model 2; Model 1 + sex, body mass index, smoking status, educational level, long term limiting illness, physical activity, serum cholesterol, and serum creatinine