Skip to main content

Table 3 Comparison of acute cystitis decision aid performance in the development [8] and validation cohorts of women with acute cystitis

From: External validation study of a clinical decision aid to reduce unnecessary antibiotic prescriptions in women with acute cystitis

Outcome

Development Cohort [8] (2002)

Validation Cohort (2009–2011)

Absolute Difference

p-value*

Number of Family Physicians

205

230

Women with complete data

331

397

Prevalence of positive cultures

208/331 (62.8%)

245/397 (61.7%)

- 1.1%

0.76

1. Accuracy

 Sensitivity

167/208 (80.3%)

202/245 (82.5%)

+ 2.1%

0.54

 Specificity

66/123 (53.7%)

54/152 (35.5%)

- 18.2%

0.005

2. Management

 Urine Cultures

107/331 (32.3%)

97/397 (24.4%)

- 7.9%

0.02

 Antibiotics Prescribed

224/331 (67.7%)

300/397 (75.6%)

+ 7.9%

0.02

 Unnecessary Antibiotics**

57/331 (17.2%)

98/397 (24.7%)

+ 7.5%

0.02

  1. *adjusted for clustering by physician
  2. **antibiotic prescription issued and subsequent urine culture was negative for bacteria