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Table 1 Number of HF patients with hyperkalaemia and incidence rates according to different hyperkalaemia definitions

From: Impact of hyperkalaemia definition on incidence assessment: implications for epidemiological research based on a large cohort study in newly diagnosed heart failure patients in primary care

Hyperkalemia definition

Patients identified with serum K+ qualifying valuea

% over total cohort (N = 19,194)

IR per 100 person-years

30-day case fatality

1-year case fatality

Serum K+ >the upper limitb

5123

26.7

7.93 (7.72–8.14)

140 (2.7 %)

899 (17.5 %)

Serum K+ ≥5.5 mmol/L

3265

17.0

4.55 (4.40–4.71)

118 (3.6 %)

647 (19.8 %)

Serum K+ ≥10 % upper limitb

2155

11.2

2.87 (2.75–2.99)

78 (3.6 %)

460 (21.3 %)

Serum K+ >10 % upper limitb

1909

9.9

2.52 (2.41–2.63)

80 (4.2 %)

437 (22.9 %)

Serum K+ ≥6 mmol/L

1097

5.7

1.40 (1.32–1.49)

65 (5.9 %)

294 (26.8 %)

Serum K+ ≥20 % upper limitb

724

3.8

0.92 (0.85–0.98)

47 (6.5 %)

198 (27.3 %)

  1. aNumber of patients with a hyperkalaemia episode identified in the follow-up
  2. bUpper bound of normal range used in the corresponding practice
  3. HF heart failure, IR incidence rate