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Table 2 Chances of cardiovascular event with or without statin over 5-year and 10-year spans

From: Communicating statin evidence to support shared decision-making

5 % 10-year risk 7.5 % 10-year risk 10 % 10-year risk 15 % 10-year risk 20 % 10-year risk 30 % 10-year risk
with statin without statin with statin without statin with statin without statin with statin without statin with statin without statin with statin without statin
3.75 % 5 % 5.63 % 7.5 % 7.5 % 10 % 11.25 % 15 % 15 % 20 % 22.5 % 30 %
ARR = 1.25 % ARR = 1.88 % ARR = 2.5 % ARR = 3.75 % ARR = 5 % ARR = 7.5 %
NNT = 80 NNT = 53 NNT = 40 NNT = 27 NNT = 20 NNT = 13
2.5 % 5-year risk 3.75 % 5-year risk 5 % 5-year risk 7.5 % 5-year risk 10 % 5-year risk 15 % 5-year risk
with statin without statin with statin without statin with statin without statin with statin without statin with statin without statin with statin without statin
1.88 % 2.5 % 2.81 % 3.75 % 3.75 % 5 % 5.63 % 7.5 % 7.5 % 10 % 11.25 % 15 %
ARR = 0.63 % ARR = 0.94 % ARR = 1.25 % ARR = 1.88 % ARR = 2.5 % ARR =3.75 %
NNT = 160 NNT = 107 NNT = 80 NNT = 53 NNT = 40 NNT = 27
  1. Based on 25 % relative risk reduction (Taylor, 2013)
  2. ARR absolute risk reduction, NNT number needed to treat