Timeliness in chronic kidney disease and albuminuria identification: a retrospective cohort study

BMC Primary Care

Table 2 Cox regression analysis of CKD registration within 12 months (1829 events of total n = 12,988)

Variable	Category	Univariate			Multivariable*
Variable	Category	HR	(95%CI)	p	HR	(95%CI)	p
Sex (female vs. male)		1.17	(1.10-1.27)	0.001	1.19	(1.08-1.30)	0.001
Age (continuous)		1.00	(1.00-1.01)	0.058	1.00	(1.00-1.01)	0.546
IMD quintile (vs. least deprived)	1 (most deprived)	0.95	(0.79-1.13)	0.324	0.92	(0.88-1.13)	0.381
	2	1.08	(0.94-1.25)		1.07	(0.96-1.23)
	3	1.10	(0.97-1.25)		1.09	(0.92-1.23)
	4	1.00	(0.88-1.13)		0.99	(0.77-1.11)
Cardiovascular disease at baseline (vs no CVD)		1.19	(1.10-1.29)	0.001	1.11	(1.00-1.23)	0.049
Diabetes at baseline (vs. no diabetes)		1.25	(1.10-1.32)	0.001	1.21	(1.08-1.37)	0.002
Hypertension at baseline (vs. no hypertension)		1.39	(1.14-1.32)	<0.001	1.36	(1.23-1.49)	<0.001
Baseline eGFR (continuous, ml/min/1.73 m²)		0.99	(0.99-1.00)	<0.001	0.99	(0.98-0.99)	<0.001
Year of joining cohort (vs. 2007)	2008	0.67	(0.53-0.84)	<0.001	0.71	(0.56-0.89)	<0.001
	2009	0.54	(0.43-0.69)		0.58	(0.46-0.74)
	2010	0.42	(0.33-0.54)		0.44	(0.34-0.57)
	2011	0.46	(0.36-0.60)		0.49	(0.38-0.63)
	2012	0.41	(0.33-0.57)		0.46	(0.34-0.60)

*adjusted for age, sex, index of multiple deprivation, cardiovascular disease, hypertension, diabetes, baseline eGFR, year of joining cohort.
Abbreviations in Table 3: CKD chronic kidney disease, IMD Index of multiple deprivation, BP blood pressure, eGFR estimated Glomerular Filtration Rate, CVD cardiovascular disease.

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