Table 5 Patient demographics and independent variables, including benzodiazepines and z-hypnotics
|  | n = 1610 | Unadjusted odds ratio (95% CI) | p-value |
|---|---|---|---|
Mean Age ± SD (range) years | 46 ± 12 (18 to 70) | 1.00 (1.00 to 1.01) | 0.432 |
Male (%) | 551 (34.2) | 1 | Â |
Female (%) | 1059 (65.8) | 1.17 (0.93 to 1.46) | 0.186 |
Deprivation (%) | |||
  SIMD quintile 1 (least deprived) | 93 (5.9) | 1 |  |
  SIMD quintile 2 | 153 (9.7) | 0.92 (0.50 to 1.70) | 0.794 |
  SIMD quintile 3 | 90 (5.7) | 1.75 (0.90 to 3.43) | 0.101 |
  SIMD quintile 4 | 264 (16.7) | 1.29 (0.73 to 2.28) | 0.373 |
  SIMD quintile 5 (most deprived) | 985 (62.1) | 1.41 (0.82 to 2.44) | 0.213 |
  SIMD unknown (not in mode) | 25 (1.6) |  |  |
†Co-morbidities (%) | |||
  0 | 1028 (63.9) | 1 |  |
  1 | 415 (25.8) | 1.20 (0.93 to 1.55) | 0.152 |
  ≥2 | 167 (10.4) | 1.12 (0.79 to 1.58) | 0.533 |
Current Smoking Status (%) | |||
  Non-smoker | 900 (56.6) | 1 |  |
  Smoker | 691 (43.4) | 1.16 (0.93 to 1.45) | 0.192 |
  Smoking status unknown (not in model) | 19 (1.2) |  |  |
SSRI use (%) | |||
  ADM for <2 y (%) | 1143 (71.0) | 1 |  |
  Same ADM for ≥2 y | 467 (29.0) | 1.94 (1.53 to 2.47) | <0.001 |
Practice (% practice pop.) | |||
  1 | 82 (5.1) | 1 |  |
  3 | 242 (15.0) | 1.48 (0.77 to 2.83) | 0.241 |
  6 | 201 (12.5) | 2.78 (1.49 to 5.18) | 0.001 |
  8 | 322 (20.0) | 1.96 (1.07 to 3.58) | 0.029 |
  9 | 181 (11.2) | 4.17 (2.22 to 7.81) | <0.001 |
  10 | 302 (18.8) | 2.60 (1.42 to 4.78) | 0.002 |
  11 | 280 (17.4) | 3.62 (1.98 to 6.66) | <0.001 |
B&Z use (%) | |||
  None | 1420 (88.2) | 1 |  |
  Long-term B&Z for ≥8 weeks | 190 (11.8) | 2.05 (1.47 to 2.86) | <0.001 |