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Table 3 Extrapolated estimates of the proportion of women aged 45–74 who would be offered symptoms-based ‘screening’ over 1 year according to different testing thresholds

From: Estimating the workload associated with symptoms-based ovarian cancer screening in primary care: an audit of electronic medical records

 

Percentage

95% CI

Any ovarian cancer symptom

51.8%

44.0%-59.7%

Any NICE guideline symptom*

24.6%

17.4%-33.0%

Any new (in last year) NICE guideline symptom*

11.9%

5.0%-18.3%

Any Index 2 symptom

20.3%

13.7%-28.5%

≥2 Index 2 symptoms

3.6%

1.0%-8.9%

  1. NICE = National Institute for Health and Clinical Excellence, CI = confidence interval.
  2. *Any one of persistent abdominal distension, feeling full (early satiety) and/or loss of appetite, pelvic or abdominal pain or increased urinary urgency and/or frequency.
  3. Estimated using Kaplan Meier.
  4. Any one of pelvic abdominal pain or discomfort, loss of appetite, increase in abdominal size, able to feel a lump in the abdomen, or vaginal discharge.
  5. Note: Extrapolations did not account for variation between practices in the proportion of women aged 45–74 with ≥1 ovarian cancer symptom. The estimated proportion of women presenting with an ovarian cancer symptom over one year varied from 32.2% (Woosehill Practice) to 69.1% (Chrisp Street Practice).