Improved persistence and adherence to diuretic fixed-dose combination therapy compared to diuretic monotherapy

BMC Primary Care

Table 2 Unadjusted antihypertensive persistence and adherence

Outcome measures	HCTZ	ARB/HCTZ	ACEI/HCTZ	BB/HCTZ
Persistence (%)	29.9	52.6	51.4	51.9
Adherence (%)	24.2	39.2	38.8	43.9
PDC^a at end of follow-up (%)	32.5	53.7	50.9	51.3
MPR^b ± SD	44.5 ± 34.5	60.5 ± 32.7	58.3 ± 34.2	62.1 ± 34.1
Days to therapy discontinuation ± SD	164.5 ± 141.8	240.1 ± 140.3	235.9 ± 140.8	238.2 ± 140.9

^aPDC denotes proportion of days covered at the end of the follow-up period. The percentage of patients who possess index class medication on day 365 of follow-up period.
^bMPR denotes medication possession ratio.

ISSN: 2731-4553