Table 2 Sensitivity, specificity, and percentage of correct classification of individuals with and without cognitive impairment and those with AD and without cognitive impairment for different cut-off scores of the crude MMSE scores obtained by GPs and by UVAs; Rome, Italy, 2005
| Â | Â | Crude MMSE obtained by GPs | Crude MMSE obtained by UVAs | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | MMSE cut-off score | Sensitivity | Specificity | % correctly classified | PPV | NPV | Sensitivity | Specificity | % correctly classified | PPV | NPV |
Classification of individuals with and without cognitive impairment | 16 | 58.8% | 85.7% | 65.9% | 92.0% | 41.1% | 53.7% | 94.1% | 64.4% | 96.2% | 42.3% |
| Â | 17 | 63.1% | 82.1% | 68.1% | 90.7% | 42.9% | 55.8% | 91.7% | 65.3% | 94.9% | 42.8% |
| Â | 18 | 66.5% | 77.4% | 69.4% | 89.1% | 44.5% | 60.1% | 91.7% | 68.5% | 95.2% | 45.3% |
| Â | 19 | 75.1% | 69.1% | 73.5% | 87.1% | 45.5% | 64.8% | 89.3% | 71.3% | 94.4% | 47.8% |
| Â | 20 | 83.7% | 64.3% | 78.6% | 86.7% | 50.0% | 70.8% | 88.1% | 75.4% | 94.3% | 52.1% |
| Â | 21 | 88.8% | 53.6% | 79.5% | 84.2% | 58.7% | 75.1% | 85.7% | 77.9% | 93.6% | 55.4% |
| Â | 22 | 92.7% | 39.3% | 78.6% | 80.9% | 63.4% | 79.4% | 79.8% | 79.5% | 91.6% | 58.3% |
| Â | 23 | 95.7% | 21.4% | 76.0% | 77.2% | 66.0% | 83.3% | 77.4% | 81.7% | 91.1% | 62.5% |
| Â | 24 | 98.7% | 4.8% | 73.8% | 74.2% | 64.3% | 87.1% | 72.6% | 83.3% | 89.8% | 67.0% |
| Â | 25 | 99.6% | 0.0% | 73.2% | 73.4% | 57.1% | 91.9% | 64.3% | 84.5% | 87.7% | 74.0% |
| Â | 26 | 100.0% | 0.0% | 73.5% | 73.5% | 0.0% | 94.9% | 59.5% | 85.5% | 86.7% | 80.7% |
Classification of individuals with AD and without cognitive impairment | 16 | 71.6% | 90.5% | 80.5% | 89.5% | 73.8% | 71.6% | 94.1% | 82.1% | 93.2% | 74.5% |
| Â | 17 | 75.8% | 85.7% | 80.5% | 85.7% | 75.8% | 73.7% | 91.7% | 82.1% | 90.9% | 75.5% |
| Â | 18 | 81.1% | 82.1% | 81.6% | 83.7% | 79.3% | 75.8% | 91.7% | 83.2% | 91.1% | 77.0% |
| Â | 19 | 83.2% | 77.4% | 80.5% | 80.6% | 80.2% | 80.0% | 89.3% | 84.4% | 89.4% | 79.8% |
| Â | 20 | 90.5% | 69.1% | 80.5% | 76.8% | 86.6% | 88.4% | 88.1% | 88.3% | 89.4% | 87.1% |
| Â | 21 | 96.8% | 64.3% | 81.6% | 75.4% | 94.7% | 91.6% | 85.7% | 88.8% | 87.9% | 90.0% |
| Â | 22 | 96.8% | 53.6% | 76.5% | 70.2% | 93.8% | 92.6% | 79.8% | 86.6% | 83.8% | 90.5% |
| Â | 23 | 96.8% | 39.3% | 69.8% | 64.3% | 91.7% | 94.7% | 77.4% | 86.6% | 82.6% | 92.9% |
| Â | 24 | 97.9% | 21.4% | 62.0% | 58.5% | 90.0% | 94.7% | 72.6% | 84.4% | 79.7% | 92.4% |
| Â | 25 | 99.0% | 4.8% | 54.8% | 54.0% | 80.0% | 97.9% | 64.3% | 82.1% | 75.6% | 96.4% |
| Â | 26 | 99.0% | 0.0% | 52.5% | 52.8% | 0.0% | 97.9% | 59.5% | 79.9% | 73.2% | 96.2% |