Skip to main content

Table 2 Sensitivity, specificity, and percentage of correct classification of individuals with and without cognitive impairment and those with AD and without cognitive impairment for different cut-off scores of the crude MMSE scores obtained by GPs and by UVAs; Rome, Italy, 2005

From: The accuracy of the MMSE in detecting cognitive impairment when administered by general practitioners: A prospective observational study

   Crude MMSE obtained by GPs Crude MMSE obtained by UVAs
  MMSE cut-off score Sensitivity Specificity % correctly classified PPV NPV Sensitivity Specificity % correctly classified PPV NPV
Classification of individuals with and without cognitive impairment 16 58.8% 85.7% 65.9% 92.0% 41.1% 53.7% 94.1% 64.4% 96.2% 42.3%
  17 63.1% 82.1% 68.1% 90.7% 42.9% 55.8% 91.7% 65.3% 94.9% 42.8%
  18 66.5% 77.4% 69.4% 89.1% 44.5% 60.1% 91.7% 68.5% 95.2% 45.3%
  19 75.1% 69.1% 73.5% 87.1% 45.5% 64.8% 89.3% 71.3% 94.4% 47.8%
  20 83.7% 64.3% 78.6% 86.7% 50.0% 70.8% 88.1% 75.4% 94.3% 52.1%
  21 88.8% 53.6% 79.5% 84.2% 58.7% 75.1% 85.7% 77.9% 93.6% 55.4%
  22 92.7% 39.3% 78.6% 80.9% 63.4% 79.4% 79.8% 79.5% 91.6% 58.3%
  23 95.7% 21.4% 76.0% 77.2% 66.0% 83.3% 77.4% 81.7% 91.1% 62.5%
  24 98.7% 4.8% 73.8% 74.2% 64.3% 87.1% 72.6% 83.3% 89.8% 67.0%
  25 99.6% 0.0% 73.2% 73.4% 57.1% 91.9% 64.3% 84.5% 87.7% 74.0%
  26 100.0% 0.0% 73.5% 73.5% 0.0% 94.9% 59.5% 85.5% 86.7% 80.7%
Classification of individuals with AD and without cognitive impairment 16 71.6% 90.5% 80.5% 89.5% 73.8% 71.6% 94.1% 82.1% 93.2% 74.5%
  17 75.8% 85.7% 80.5% 85.7% 75.8% 73.7% 91.7% 82.1% 90.9% 75.5%
  18 81.1% 82.1% 81.6% 83.7% 79.3% 75.8% 91.7% 83.2% 91.1% 77.0%
  19 83.2% 77.4% 80.5% 80.6% 80.2% 80.0% 89.3% 84.4% 89.4% 79.8%
  20 90.5% 69.1% 80.5% 76.8% 86.6% 88.4% 88.1% 88.3% 89.4% 87.1%
  21 96.8% 64.3% 81.6% 75.4% 94.7% 91.6% 85.7% 88.8% 87.9% 90.0%
  22 96.8% 53.6% 76.5% 70.2% 93.8% 92.6% 79.8% 86.6% 83.8% 90.5%
  23 96.8% 39.3% 69.8% 64.3% 91.7% 94.7% 77.4% 86.6% 82.6% 92.9%
  24 97.9% 21.4% 62.0% 58.5% 90.0% 94.7% 72.6% 84.4% 79.7% 92.4%
  25 99.0% 4.8% 54.8% 54.0% 80.0% 97.9% 64.3% 82.1% 75.6% 96.4%
  26 99.0% 0.0% 52.5% 52.8% 0.0% 97.9% 59.5% 79.9% 73.2% 96.2%
  1. Note: Individuals whose score was equal to or lower than the reported cut-off value were classified as having cognitive impairment in the first section of the table and as having AD in the second section of the table.