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Table 3 Test accuracy of NT-proBNP and the clinical risk score for identifying left ventricular systolic dysfunction.*

From: Natriuretic peptide vs. clinical information for diagnosis of left ventricular systolic dysfunction in primary care

 

True Positive

False Positive

False Negative

True Negative

Sensitivity (%)

Specificity (%)

Likelihood ratio of negative result (95% CI)

NT-proBNP (< 98.5 pg/ml)

21

282

2

237

91 (71 to 98)

46 (41 to 50)

0.19 (0.05 to 0.71)

Risk score (< 1.11)

21

189

2

330

91 (71 to 98)

64 (59 to 67)

0.14 (0.04 to 0.51)

  1. *At cut-off points with comparable high sensitivity and moderate specificity in order to rule out left ventricular dysfunction in case of a negative result (SnNout; very high sensitivity: negative result rules out the diagnosis/disease. Values in parentheses are 95% confidence intervals.