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Table 3 General characteristics of patients with diabetes mellitus by type of cardiovascular prevention (primary, secondary).

From: Use of aspirin for primary and secondary prevention of cardiovascular disease in diabetic patients in an ambulatory care setting in Spain

Characteristics Primary n = 3,273 Secondary n = 867 Total n = 4,140 p
Mean age (SD), years 62.3 (14.1) 70.9 (10.0) 64.1 (13.8) 0.000
Sex (males, %) 46.3 60.7 49.3 0.000
SS status (active, %) 37.4 11.2 31.9 0.000
Time since diagnosis (SD), months 43.2 (37.5) 52.6 (49.1) 45.2 (40.4) 0.000
Follow-up per protocol (SD), visits 3.9 (3.2) 4.4 (3.5) 4.0 (3.3) 0.000
CV history     
Arterial hypertension 49.2 55.9 50.6 0.002
Hypercholesterolemia 34.9 47.5 37.6 0.001
Active smoking 19.3 16.0 18.9 0.026
Obesity (BMI < 29) 47.0 45.2 46.6 ns
Other co-morbidities     
Heart failure 2.4 8.1 3.6 0.000
Renal failure 1.0 3.2 1.5 0.000
Liver failure 2.8 3.9 3.0 ns
COPD 4.8 12.9 6.5 0.000
Depressive syndrome 14.2 14.6 14.3 ns
Prostatic hypertrophy 4.3 11.1 5.7 0.000
Treatment     
Acetyl salicylic acid 20.8 60.8 29.2  
Other antiaggregants, OACs 5.1 30.9 10.5 0.000
Clinical parameters     
Body mass index (SD) 30.3 (5.3) 29.9 (4.9) 30.2 (5.2) ns
Systolic blood pressure (SD) 135.3 (17.2) 135.4 (17.9) 135.4 (17.4) ns
Diastolic blood pressure (SD) 78.1 (9.4) 75.7 (9.0) 77.5 (9.3) 0.000
Total cholesterol (SD) 206.9 (41.3) 192.9 (39.9) 203.9 (41.4) 0.000
LDL-C (SD) 133.7 (35.4) 123.7 (35.5) 131.6 (35.6) 0.000
Glycated hemoglobin A1c (SD) 7.2 (1.5) 7.4 (1.4) 7.3 (1.5) 0.014
CVR index (SD) 21.1 (9.1) 25.2 (9.9) 22.1 (9.3) 0.000
Therapeutic targets     
BP (<130/80 mmHg) 46.1 48.0 46.5 ns
Total cholesterol (<200 mg/dL) 44.1 59.8 47.5 0.000
LDL-C (<100 mg/dL) 16.5 26.9 18.7 0.000
Glycated hemoglobin A1c (<6.5%) 35.2 27.2 33.4 0.001
  1. Values are given as percentage or mean (SD: standard deviation); p: statistical significance; SS: social security; CV: cardiovascular; OACs: oral anticoagulants; CVR: cardiovascular risk; BP: blood pressure (mmHg); LDL-C: low density lipoprotein cholesterol (mg/dL); COPD: chronic obstructive pulmonary disease.