Table 3 General characteristics of patients with diabetes mellitus by type of cardiovascular prevention (primary, secondary).
Characteristics | Primary n = 3,273 | Secondary n = 867 | Total n = 4,140 | p |
|---|---|---|---|---|
Mean age (SD), years | 62.3 (14.1) | 70.9 (10.0) | 64.1 (13.8) | 0.000 |
Sex (males, %) | 46.3 | 60.7 | 49.3 | 0.000 |
SS status (active, %) | 37.4 | 11.2 | 31.9 | 0.000 |
Time since diagnosis (SD), months | 43.2 (37.5) | 52.6 (49.1) | 45.2 (40.4) | 0.000 |
Follow-up per protocol (SD), visits | 3.9 (3.2) | 4.4 (3.5) | 4.0 (3.3) | 0.000 |
CV history | ||||
Arterial hypertension | 49.2 | 55.9 | 50.6 | 0.002 |
Hypercholesterolemia | 34.9 | 47.5 | 37.6 | 0.001 |
Active smoking | 19.3 | 16.0 | 18.9 | 0.026 |
Obesity (BMI < 29) | 47.0 | 45.2 | 46.6 | ns |
Other co-morbidities | ||||
Heart failure | 2.4 | 8.1 | 3.6 | 0.000 |
Renal failure | 1.0 | 3.2 | 1.5 | 0.000 |
Liver failure | 2.8 | 3.9 | 3.0 | ns |
COPD | 4.8 | 12.9 | 6.5 | 0.000 |
Depressive syndrome | 14.2 | 14.6 | 14.3 | ns |
Prostatic hypertrophy | 4.3 | 11.1 | 5.7 | 0.000 |
Treatment | ||||
Acetyl salicylic acid | 20.8 | 60.8 | 29.2 | |
Other antiaggregants, OACs | 5.1 | 30.9 | 10.5 | 0.000 |
Clinical parameters | ||||
Body mass index (SD) | 30.3 (5.3) | 29.9 (4.9) | 30.2 (5.2) | ns |
Systolic blood pressure (SD) | 135.3 (17.2) | 135.4 (17.9) | 135.4 (17.4) | ns |
Diastolic blood pressure (SD) | 78.1 (9.4) | 75.7 (9.0) | 77.5 (9.3) | 0.000 |
Total cholesterol (SD) | 206.9 (41.3) | 192.9 (39.9) | 203.9 (41.4) | 0.000 |
LDL-C (SD) | 133.7 (35.4) | 123.7 (35.5) | 131.6 (35.6) | 0.000 |
Glycated hemoglobin A1c (SD) | 7.2 (1.5) | 7.4 (1.4) | 7.3 (1.5) | 0.014 |
CVR index (SD) | 21.1 (9.1) | 25.2 (9.9) | 22.1 (9.3) | 0.000 |
Therapeutic targets | ||||
BP (<130/80 mmHg) | 46.1 | 48.0 | 46.5 | ns |
Total cholesterol (<200 mg/dL) | 44.1 | 59.8 | 47.5 | 0.000 |
LDL-C (<100 mg/dL) | 16.5 | 26.9 | 18.7 | 0.000 |
Glycated hemoglobin A1c (<6.5%) | 35.2 | 27.2 | 33.4 | 0.001 |