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Table 2 Clinical and Demographic Data of Patient Cohort

From: Symptomatic hypogammaglobulinemia in infancy and childhood – clinical outcome and in vitro immune responses

  

THGI

Non Transient

p

Demographics

No of Patients

17 (53%)

15 (47%)

> 0.05

 

Males

15 (88%)

9 (60%)

> 0.05

 

Females

2 [30]

6 [31]

> 0.05

 

Average age at Diagnosis

3.6 years

3.1 years

> 0.05

Clinical Data

ENT

10 (59%)

12 (80%)

> 0.05

 

Respiratory

15 (88%)

11 (73%)

> 0.05

 

GI

2 [32]

2 [33]

> 0.05

 

Atopy

11 (65%)

9 (60%)

> 0.05

 

Family History

4 (24%)

3 (20%)

> 0.05

Diagnosis

IgAD

9 (53%)

7 (48%)

> 0.05

 

IgGD

12 (71%)

10 (68%)

> 0.05

 

IgMD

2 [34]

3 (20%)

> 0.05

Treatment

Antibiotics

4 (24%)

8 (53%)

> 0.05

 

IVIg

2 [35]

1 [36]

> 0.05

Outcome

No Infections

14 (83%)

13 (87%)

> 0.05

Follow-up (years)

Age at last follow-up

7.1

5.5

> 0.05

 

Length of follow-up

3.5

2.5

> 0.05

  1. THGI – Transient Hypogammglobulinemia of Childhood
  2. Non Transient – Hypogammaglobulinemic patients who did not correct during follow-up
  3. IgAD – IgA 2SD bellow age specific norms
  4. IgGD – One or more IgG isotype 2SD bellow age specific norms
  5. IgMD – IgM 2SD bellow age specific norms