Table 6 Discontinuation.
Discontinued | ||||
|---|---|---|---|---|
Reason and statin | Number of trials | Duration (wks) | Number | Percent |
Discontinuation for any reason | ||||
Atorvastatin | 3 | 16/52 | 59/1066 | 6 |
Cerivastatin | 4 | 24–32 | 27/754 | 4 |
Fluvastatin | 6 | 12–24 | 54/518 | 10 |
Lovastatin | 5 | 12/18 wks | 64/879 | 7 |
Pravastatin | 17 | 12 wks – 5 yrs | 707/5831 | 12 |
Rosuvastatin | 1 | 12 | 15/235 | 6 |
Simvastatin | 13 | 12 wks – 5.4 yrs | 1605/13898 | 12 |
Placebo | 16 | 13 wks – 5.4 yrs | 2692/17314 | 16 |
Discontinuation because of adverse events | ||||
Atorvastatin | 1 | 52 | 7/227 | 3 |
Cerivastatin | 2 | 24–32 | 27/754 | 4 |
Fluvastatin | 7 | 12–24 | 43/860 | 5 |
Lovastatin | 9 | 12 wks – 2 yrs | 26/1180 | 2 |
Pravastatin | 28 | 12 wks – 5 yrs | 136/5403 | 3 |
Rosuvastatin | 1 | 12 | 8/235 | 3 |
Simvastatin | 17 | 12 wks – 5.4 yrs | 199/5133 | 4 |
Placebo | 24 | 13 wks – 5.4 yrs | 280/6072 | 5 |