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Table 5 Diagnostic accuracy of age-specific PSA levels

From: Prostate-specific antigen testing accuracy in community practice

Age PSA cutoff (ng/mL) Sensitivity (%) Specificity (%) LR + (95% CI) LR – (95% CI)
40 – 49 2.5 85 42 1.47 (1.11, 1.93) 0.35 (0.13, 0.96)
50 – 59 3.5 86 38 1.38 (1.25, 1.54) 0.36 (0.24, 0.56)
60 – 69 4.5 78 36 1.22 (1.14, 1.32) 0.60 (0.49, 0.74)
≥ 70 6.5 70 49 1.38 (1.24, 1.53) 0.61 (0.52, 0.73)
  1. Abbreviations: PSA = prostate-specific antigen. LR+ = likelihood ratio for a positive test. LR- = likelihood ratio for a negative test. CI = confidence interval.