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Table 1 Characteristics of patients with elevated and normal calcium concentrations 1995–2000 and 2008–2010, men and women, at Tibro Health Care Centre, Sweden

From: Quality of life and health care consumption in primary care patients with elevated serum calcium concentrations in - a prospective, case control, study

  Patients with elevated calcium concentrations Patients with normal calcium concentrations Comparison between the groups
  Total Men Women Total Men Women Total p -value Men p -value Women p -value
Variables Mean Percentile Mean Percentile Mean Percentile Mean Percentile Mean Percentile Mean Percentile    
Data from register 1995–2000                
Number 127   28   99   254   56   198     
Age, January 1st 1995 61.4 36.6- 80.0 55.6 31.8- 77.0 63.0 38.8- 80.2 61.3 36.3- 80.0 55.5 39.0- 80.3 62.9 31.0- 77.0 n.s n.s n.s
Age, range 18–94   18–82   18–94   18–91   18–82   18–91     
S- Calcium1 2.66 2.56- 2.78 2.72 2.57- 2.88 2.64 2.56- 2.78 2.33 2.21- 2.43 2.31 2.19- 2.42 2.33 2.21- 2.44 <0.001 <0.001 <0.001
Data from clinical investigation 2008–2010                
Number 63   12   51   133   33   100     
Age, January 1st 2011 71.4 49.4- 89.0 67.7 49.2- 80.0 72.3 52.0- 89.0 70.0 45.2- 88.0 66.8 45.2- 84.4 71.0 45.8- 90.0 n.s n.s n.s
Age, range 31–97   45–82   31–97   30–99   31–99   30–97     
P- Calcium2 2.42 2.26- 2.59 2.39 2.18- 2.55 2.43 2.27- 2.64 2.35 2.22- 2.47 2.32 2.21- 2.42 2.36 2.23- 2.48 <0.001 0.085 0.003
Ionised Calcium3 1.29 1.22- 1.40 1.28 1.24- 1.31 1.29 1.22- 1.44 1.23 1.18- 1.27 1.22 1.16- 1.26 1.23 1.18- 1.28 <0.001 <0.001 <0.001
Parathyroid hormone4 68 20- 118 60 14- 136 69 21- 113 58 26- 107 57 22- 104 59 28- 113 n.s n.s n.s
  1. Notes: Data are means (SD), n.s = not significant, Age in years. Reference range 1Serum Calcium analysed in whole blood (mmol/L) 2.15–2.55 (mmol/L), 2Plasma Calcium (mmol/L) 2.15–2.50, 3Ionised Calcium (mmol/L) 1.15–1.35, 4Parathyroid hormone (ng/L) 15–65.