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Table 1 Insulin titration algorithm

From: An exploratory trial of insulin initiation and titration among patients with type 2 diabetes in the primary care setting with retrospective continuous glucose monitoring as an adjunct: INITIATION study protocol

Fasting BGL (mmol/L)*

Glargine titration

2 hr post prandial BGL (mmol/L)*

Glulisine titration

<4.0

Reduce by 2–4 units

<4.5

Reduce by 2–4 units

4.0-7.0

No change

4.5-7.0

No change

7.1-8.0

Add 2 units

7.1-10.0

Add 0–2 units#

8.1-10.0

Add 4 units

10.1-12.0

Add 2 units

>10.0

Add 6 units

12.1-14.0

Add 4–6 units

> 14.0

Add 6–8 units#

  1. BGL = Blood Glucose Level.
  2. #Upon GP’s discretion.
  3. *For values in mg/dl multiply by 18.