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Table 1 Insulin titration algorithm

From: An exploratory trial of insulin initiation and titration among patients with type 2 diabetes in the primary care setting with retrospective continuous glucose monitoring as an adjunct: INITIATION study protocol

Fasting BGL (mmol/L)* Glargine titration 2 hr post prandial BGL (mmol/L)* Glulisine titration
<4.0 Reduce by 2–4 units <4.5 Reduce by 2–4 units
4.0-7.0 No change 4.5-7.0 No change
7.1-8.0 Add 2 units 7.1-10.0 Add 0–2 units#
8.1-10.0 Add 4 units 10.1-12.0 Add 2 units
>10.0 Add 6 units 12.1-14.0 Add 4–6 units
> 14.0 Add 6–8 units#
  1. BGL = Blood Glucose Level.
  2. #Upon GP’s discretion.
  3. *For values in mg/dl multiply by 18.